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19 results

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Page 1
Genome-wide in vivo CRISPR screens identify GATOR1 complex as a tumor suppressor in Myc-driven lymphoma.
Potts MA, Mizutani S, Deng Y, Vaidyanathan S, Ting KE, Giner G, Sridhar S, Shenoy G, Liao Y, Diepstraten ST, Kueh AJ, Pal M, Healey G, Tai L, Wang Z, König C, Kaloni D, Whelan L, Milevskiy MJG, Coughlan HD, Pomilio G, Wei AH, Visvader JE, Papenfuss AT, Wilcox S, Jeyasekharan AD, Shi W, Lelliott EJ, Kelly GL, Brown KK, Strasser A, Herold MJ. Potts MA, et al. Nat Commun. 2025 Aug 21;16(1):7582. doi: 10.1038/s41467-025-62615-y. Nat Commun. 2025. PMID: 40841511 Free PMC article.
Advancing the genetic engineering toolbox by combining AsCas12a knock-in mice with ultra-compact screening.
Jin W, Deng Y, La Marca JE, Lelliott EJ, Diepstraten ST, König C, Tai L, Snetkova V, Dorighi KM, Hoberecht L, Hedditch MG, Whelan L, Healey G, Fayle D, Lau K, Potts MA, Chen MZ, Johnston APR, Liao Y, Shi W, Kueh AJ, Haley B, Fortin JP, Herold MJ. Jin W, et al. Among authors: potts ma. Nat Commun. 2025 Jan 30;16(1):974. doi: 10.1038/s41467-025-56282-2. Nat Commun. 2025. PMID: 39885149 Free PMC article.
Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance.
Deng Y, Diepstraten ST, Potts MA, Giner G, Trezise S, Ng AP, Healey G, Kane SR, Cooray A, Behrens K, Heidersbach A, Kueh AJ, Pal M, Wilcox S, Tai L, Alexander WS, Visvader JE, Nutt SL, Strasser A, Haley B, Zhao Q, Kelly GL, Herold MJ. Deng Y, et al. Among authors: potts ma. Nat Commun. 2022 Aug 12;13(1):4739. doi: 10.1038/s41467-022-32485-9. Nat Commun. 2022. PMID: 35961968 Free PMC article.
Author Correction: Generation of a CRISPR activation mouse that enables modelling of aggressive lymphoma and interrogation of venetoclax resistance.
Deng Y, Diepstraten ST, Potts MA, Giner G, Trezise S, Ng AP, Healey G, Kane SR, Cooray A, Behrens K, Heidersbach A, Kueh AJ, Pal M, Wilcox S, Tai L, Alexander WS, Visvader JE, Nutt SL, Strasser A, Haley B, Zhao Q, Kelly GL, Herold MJ. Deng Y, et al. Among authors: potts ma. Nat Commun. 2022 Aug 25;13(1):5007. doi: 10.1038/s41467-022-32817-9. Nat Commun. 2022. PMID: 36008403 Free PMC article. No abstract available.
Membrane budding is a major mechanism of in vivo platelet biogenesis.
Potts KS, Farley A, Dawson CA, Rimes J, Biben C, de Graaf C, Potts MA, Stonehouse OJ, Carmagnac A, Gangatirkar P, Josefsson EC, Anttila C, Amann-Zalcenstein D, Naik S, Alexander WS, Hilton DJ, Hawkins ED, Taoudi S. Potts KS, et al. Among authors: potts ma. J Exp Med. 2020 Sep 7;217(9):e20191206. doi: 10.1084/jem.20191206. J Exp Med. 2020. PMID: 32706855 Free PMC article.
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