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65 results

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Page 1
Heterozygous BTNL8 variants in individuals with multisystem inflammatory syndrome in children (MIS-C).
Bellos E, Santillo D, Vantourout P, Jackson HR, Duret A, Hearn H, Seeleuthner Y, Talouarn E, Hodeib S, Patel H, Powell O, Yeoh S, Mustafa S, Habgood-Coote D, Nichols S, Estramiana Elorrieta L, D'Souza G, Wright VJ, Estrada-Rivadeneyra D, Tremoulet AH, Dummer KB, Netea SA, Condino-Neto A, Lau YL, Núñez Cuadros E, Toubiana J, Holanda Pena M, Rieux-Laucat F, Luyt CE, Haerynck F, Mège JL, Chakravorty S, Haddad E, Morin MP, Metin Akcan Ö, Keles S, Emiroglu M, Alkan G, Tüter Öz SK, Elmas Bozdemir S, Morelle G, Volokha A, Kendir-Demirkol Y, Sözeri B, Coskuner T, Yahsi A, Gulhan B, Kanik-Yuksek S, Bayhan GI, Ozkaya-Parlakay A, Yesilbas O, Hatipoglu N, Ozcelik T, Belot A, Chopin E, Barlogis V, Sevketoglu E, Menentoglu E, Gayretli Aydin ZG, Bloomfield M, AlKhater SA, Cyrus C, Stepanovskiy Y, Bondarenko A, Öz FN, Polat M, Fremuth J, Lebl J, Geraldo A, Jouanguy E; COVID-19 Human Genetic Effort; DIAMONDS; EUCLIDS; Carter MJ, Wellman P, Peters M, Pérez de Diego R, Edwards LA, Chiu C, Noursadeghi M, Bolze A, Shimizu C, Kaforou M, Hamilton MS, Herberg JA, Schmitt EG, Rodriguez-Palmero A, Pujol A, Kim J, Cobat A, Abel L, Zhang SY, Casanova JL, Kuijpers TW, Burns JC, Levin M, Hayday AC, Sanc… See abstract for full author list ➔ Bellos E, et al. Among authors: powell o. J Exp Med. 2024 Dec 2;221(12):e20240699. doi: 10.1084/jem.20240699. Epub 2024 Nov 22. J Exp Med. 2024. PMID: 39576310 Free PMC article.
Genomic investigations of unexplained acute hepatitis in children.
Morfopoulou S, Buddle S, Torres Montaguth OE, Atkinson L, Guerra-Assunção JA, Moradi Marjaneh M, Zennezini Chiozzi R, Storey N, Campos L, Hutchinson JC, Counsell JR, Pollara G, Roy S, Venturini C, Antinao Diaz JF, Siam A, Tappouni LJ, Asgarian Z, Ng J, Hanlon KS, Lennon A, McArdle A, Czap A, Rosenheim J, Andrade C, Anderson G, Lee JCD, Williams R, Williams CA, Tutill H, Bayzid N, Martin Bernal LM, Macpherson H, Montgomery KA, Moore C, Templeton K, Neill C, Holden M, Gunson R, Shepherd SJ, Shah P, Cooray S, Voice M, Steele M, Fink C, Whittaker TE, Santilli G, Gissen P, Kaufer BB, Reich J, Andreani J, Simmonds P, Alrabiah DK, Castellano S, Chikowore P, Odam M, Rampling T, Houlihan C, Hoschler K, Talts T, Celma C, Gonzalez S, Gallagher E, Simmons R, Watson C, Mandal S, Zambon M, Chand M, Hatcher J, De S, Baillie K, Semple MG; DIAMONDS Consortium; PERFORM Consortium; ISARIC 4C Investigators; Martin J, Ushiro-Lumb I, Noursadeghi M, Deheragoda M, Hadzic N, Grammatikopoulos T, Brown R, Kelgeri C, Thalassinos K, Waddington SN, Jacques TS, Thomson E, Levin M, Brown JR, Breuer J. Morfopoulou S, et al. Nature. 2023 May;617(7961):564-573. doi: 10.1038/s41586-023-06003-w. Epub 2023 Mar 30. Nature. 2023. PMID: 36996872 Free PMC article.
Adeno-associated virus 2 infection in children with non-A-E hepatitis.
Ho A, Orton R, Tayler R, Asamaphan P, Herder V, Davis C, Tong L, Smollett K, Manali M, Allan J, Rawlik K, McDonald SE, Vink E, Pollock L, Gannon L, Evans C, McMenamin J, Roy K, Marsh K, Divala T, Holden MTG, Lockhart M, Yirrell D, Currie S, O'Leary M, Henderson D, Shepherd SJ, Jackson C, Gunson R, MacLean A, McInnes N, Bradley-Stewart A, Battle R, Hollenbach JA, Henderson P, Odam M, Chikowore P, Oosthuyzen W, Chand M, Hamilton MS, Estrada-Rivadeneyra D, Levin M, Avramidis N, Pairo-Castineira E, Vitart V, Wilkie C; DIAMONDS Consortium; ISARIC4C Investigators; Palmarini M, Ray S, Robertson DL, da Silva Filipe A, Willett BJ, Breuer J, Semple MG, Turner D, Baillie JK, Thomson EC. Ho A, et al. Nature. 2023 May;617(7961):555-563. doi: 10.1038/s41586-023-05948-2. Epub 2023 Mar 30. Nature. 2023. PMID: 36996873 Free PMC article.
Shared neutrophil and T cell dysfunction is accompanied by a distinct interferon signature during severe febrile illnesses in children.
Patel H, Carter MJ, Jackson H, Powell O, Fish M, Terranova-Barberio M, Spada F, Petrov N, Wellman P, Darnell S, Mustafa S, Todd K, Bishop C, Cohen JM, Kenny J, van den Berg S, Sun T, Davis F, Jennings A, Timms E, Thomas J, Nyirendra M, Nichols S, Estamiana Elorieta L, D'Souza G, Wright V, De T, Habgood-Coote D, Ramnarayan P, Tissières P, Whittaker E, Herberg J, Cunnington A, Kaforou M, Ellis R, Malim MH, Tibby SM, Shankar-Hari M, Levin M; DIAMONDS Consortium. Patel H, et al. Among authors: powell o. Nat Commun. 2024 Sep 19;15(1):8224. doi: 10.1038/s41467-024-52246-0. Nat Commun. 2024. PMID: 39300098 Free PMC article.
Potential approaches to create ultimate genotypes in crops and livestock.
Hayes BJ, Mahony TJ, Villiers K, Warburton C, Kemper KE, Dinglasan E, Robinson H, Powell O, Voss-Fels K, Godwin ID, Hickey LT. Hayes BJ, et al. Among authors: powell o. Nat Genet. 2024 Nov;56(11):2310-2317. doi: 10.1038/s41588-024-01942-0. Epub 2024 Oct 14. Nat Genet. 2024. PMID: 39402155 Review.
A wheat tandem kinase activates an NLR to trigger immunity.
Chen R, Chen J, Powell OR, Outram MA, Arndell T, Gajendiran K, Wang YL, Lubega J, Xu Y, Ayliffe MA, Blundell C, Figueroa M, Sperschneider J, Vanhercke T, Kanyuka K, Tang D, Zhong G, Gardener C, Yu G, Gourdoupis S, Jaremko Ł, Matny O, Steffenson BJ, Boshoff WHP, Meyer WB, Arold ST, Dodds PN, Wulff BBH. Chen R, et al. Among authors: powell or. Science. 2025 Mar 28;387(6741):1402-1408. doi: 10.1126/science.adp5034. Epub 2025 Mar 27. Science. 2025. PMID: 40146821
A multi-platform approach to identify a blood-based host protein signature for distinguishing between bacterial and viral infections in febrile children (PERFORM): a multi-cohort machine learning study.
Jackson HR, Zandstra J, Menikou S, Hamilton MS, McArdle AJ, Fischer R, Thorne AM, Huang H, Tanck MW, Jansen MH, De T, Agyeman PKA, Von Both U, Carrol ED, Emonts M, Eleftheriou I, Van der Flier M, Fink C, Gloerich J, De Groot R, Moll HA, Pokorn M, Pollard AJ, Schlapbach LJ, Tsolia MN, Usuf E, Wright VJ, Yeung S, Zavadska D, Zenz W, Coin LJM, Casals-Pascual C, Cunnington AJ, Martinon-Torres F, Herberg JA, de Jonge MI, Levin M, Kuijpers TW, Kaforou M; PERFORM consortium. Jackson HR, et al. Lancet Digit Health. 2023 Nov;5(11):e774-e785. doi: 10.1016/S2589-7500(23)00149-8. Lancet Digit Health. 2023. PMID: 37890901 Free article.
Septoria tritici blotch resistance gene Stb15 encodes a lectin receptor-like kinase.
Hafeez AN, Chartrain L, Feng C, Cambon F, Clarke M, Griffiths S, Hayta S, Jiang M, Keller B, Kirby R, Kolodziej MC, Powell OR, Smedley MA, Steuernagel B, Xian W, Wingen LU, Cheng S, Saintenac C, Wulff BBH, Brown JKM. Hafeez AN, et al. Among authors: powell or. Nat Plants. 2025 Mar;11(3):410-420. doi: 10.1038/s41477-025-01920-2. Epub 2025 Mar 14. Nat Plants. 2025. PMID: 40087541 Free PMC article.
Immunity to Streptococcus pyogenes and Common Respiratory Viruses at Age 0 to 4 Years After COVID-19 Restrictions.
Dokal K, Channon-Wells S, Davis C, Estrada-Rivadeneyra D, Huse KK, Lias A, Hamilton S, Guy RL, Lamagni T, Nichols S, Taylor A, Agyeman PKA, Anpananthar A, Basmaci R, Carrol ED, Carter MJ, De T, de Jonge MI, Emonts M, Elorrieta LE, Fidler K, Kolnik M, Kuijpers TW, Martinon-Torres F, Moll H, Mommert-Tripon M, Neshat S, Nyirenda-Nyang'wa M, O'Riordan S, Owens DR, Pathan N, Paulus S, Peters MJ, Pokorn M, Pollard AJ, Rivero-Calle I, Rojo P, Romani L, Rughani P, Schlapbach LJ, Schweintzger NA, Shen CF, Sulik A, Tsolia M, Usuf E, van der Flier M, Vermont C, von Both U, Wellman P, Wright VJ, Yeung S, Zavadska D, Cunnington AJ, Fink C, Herberg J, Kaforou M, Sriskandan S, Levin M, Parks T; PERFORM and DIAMONDS consortiums. Dokal K, et al. JAMA Netw Open. 2025 Oct 1;8(10):e2537808. doi: 10.1001/jamanetworkopen.2025.37808. JAMA Netw Open. 2025. PMID: 41091464 Free PMC article.
Advancing artificial intelligence to help feed the world.
Hayes BJ, Chen C, Powell O, Dinglasan E, Villiers K, Kemper KE, Hickey LT. Hayes BJ, et al. Among authors: powell o. Nat Biotechnol. 2023 Sep;41(9):1188-1189. doi: 10.1038/s41587-023-01898-2. Nat Biotechnol. 2023. PMID: 37524959 No abstract available.
65 results