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Page 1
Showing results for placental b
Search for Pracontal B instead (2 results)
Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens.
Karvas RM, Khan SA, Verma S, Yin Y, Kulkarni D, Dong C, Park KM, Chew B, Sane E, Fischer LA, Kumar D, Ma L, Boon ACM, Dietmann S, Mysorekar IU, Theunissen TW. Karvas RM, et al. Cell Stem Cell. 2022 May 5;29(5):810-825.e8. doi: 10.1016/j.stem.2022.04.004. Cell Stem Cell. 2022. PMID: 35523141 Free PMC article.
Trophoblast organoids derived from placental villi provide a 3D model system of human placental development, but access to first-trimester tissues is limited. ...The generation of trophoblast organoids from naive hPSCs provides an accessible 3D model system of the d …
Trophoblast organoids derived from placental villi provide a 3D model system of human placental development, but access to fir …
Fetuin-B and oxidative stress disrupt placental trophoblasts during maternal undernourishment.
Camilliere M, Verde MR, Wolin MS, Rabadi MM, Ratliff BB. Camilliere M, et al. J Obstet Gynaecol. 2025 Dec;45(1):2460545. doi: 10.1080/01443615.2025.2460545. Epub 2025 Feb 6. J Obstet Gynaecol. 2025. PMID: 39916407 Free article.
RESULTS: Studies indicated that MUN and oxidative stress upregulated fetuin-B in the placenta. This relationship displayed a positive feedback loop as fetuin-B, in turn, promoted oxidative stress through activation of TLR4. ...MUN was found to increase oxidat …
RESULTS: Studies indicated that MUN and oxidative stress upregulated fetuin-B in the placenta. This relationship displayed a p …
Blood Flow and Respiratory Gas Exchange in the Human Placenta at Term: A Data Update.
Vaupel P, Multhoff G. Vaupel P, et al. Adv Exp Med Biol. 2022;1395:379-384. doi: 10.1007/978-3-031-14190-4_62. Adv Exp Med Biol. 2022. PMID: 36527666
These data sets include (a) principal factors affecting placental gas transfer, e.g., maternal blood flow through the intervillous space (IVS) (500 mL/min) and foeto-placental blood flow (480 mL/min), and (b) O(2), CO(2) and pH levels in the materno-placen …
These data sets include (a) principal factors affecting placental gas transfer, e.g., maternal blood flow through the intervillous sp …
Extracellular vesicles derived from Akkermansia muciniphila promote placentation and mitigate preeclampsia in a mouse model.
Chen Y, Ou Z, Pang M, Tao Z, Zheng X, Huang Z, Wen D, Li Q, Zhou R, Chen P, Situ B, Sheng C, Huang Y, Yue X, Zheng L, Huang L. Chen Y, et al. J Extracell Vesicles. 2023 May;12(5):e12328. doi: 10.1002/jev2.12328. J Extracell Vesicles. 2023. PMID: 37165987 Free PMC article.
Also, we found that administration with Am could significantly attenuate systolic blood pressure, promote foetal growth and improve the placental pathology in mice with PE. Moreover, Am-derived extracellular vesicles (AmEVs) were transferred from the gastrointestinal (GI) …
Also, we found that administration with Am could significantly attenuate systolic blood pressure, promote foetal growth and improve the p …
Excess Neprilysin in Placental EVs Impairs CNP-NPRB-Mediated Vasodilation to Trigger Preeclamptic Hypertension.
He C, Du Y, Chen R, Qiu Y, Huang J, Lin L, Kilby MD, Fu Y, Qi H, Baker PN, Tong C. He C, et al. Circ Res. 2025 Jun 6;136(12):1526-1541. doi: 10.1161/CIRCRESAHA.124.325673. Epub 2025 Apr 30. Circ Res. 2025. PMID: 40304042
BACKGROUND: Preeclampsia is a placenta-origin pregnancy complication. Although its development has long been divided into 2 stages: abnormal placentation (stage I) and the release of factors from the hypoperfused placenta into circulation, triggering preeclam …
BACKGROUND: Preeclampsia is a placenta-origin pregnancy complication. Although its development has long been divided into 2 stages: a …
New Ideas for the Prevention and Treatment of Preeclampsia and Their Molecular Inspirations.
Sakowicz A, Bralewska M, Rybak-Krzyszkowska M, Grzesiak M, Pietrucha T. Sakowicz A, et al. Int J Mol Sci. 2023 Jul 28;24(15):12100. doi: 10.3390/ijms241512100. Int J Mol Sci. 2023. PMID: 37569476 Free PMC article. Review.
It is known that the pathomechanism of preeclampsia is strongly related to inflammation and oxidative stress, which influence placentation and provoke endothelial dysfunction in the mother. However, as of yet, no "key players" regulating all these processes have been disco …
It is known that the pathomechanism of preeclampsia is strongly related to inflammation and oxidative stress, which influence placentatio …
A regulatory role for neurokinin B in placental physiology and pre-eclampsia.
Page NM, Woods RJ, Lowry PJ. Page NM, et al. Regul Pept. 2001 Apr 20;98(3):97-104. doi: 10.1016/s0167-0115(00)00239-1. Regul Pept. 2001. PMID: 11231038 Review.
We have found an abundant source of peripheral NKB in the human and rat placenta. In this review we describe the discovery of NKB in the placenta and examine its possible role in placental physiology and pre-eclampsia (PE). Excessive secretion of placental …
We have found an abundant source of peripheral NKB in the human and rat placenta. In this review we describe the discovery of NKB in …
Mature naive B cells are retained in the placental intervillous blood and positively associate with specific chemokines in full-term healthy pregnancy.
Solders M, Lundell AC, Gorchs L, Gidlöf S, Tiblad E, Kaipe H. Solders M, et al. Am J Reprod Immunol. 2019 Sep;82(3):e13154. doi: 10.1111/aji.13154. Epub 2019 Jun 18. Am J Reprod Immunol. 2019. PMID: 31166050
Pregnancy-related hormones could influence B-cell lymphopoiesis in the bone marrow, but B cells may also be recruited to the placenta. ...Migration assays showed that placental explant-derived supernatants attract B cells. CONCLUSION: These resu …
Pregnancy-related hormones could influence B-cell lymphopoiesis in the bone marrow, but B cells may also be recruited to the …
PIBF1 regulates trophoblast syncytialization and promotes cardiovascular development.
Lee JG, Yon JM, Kim G, Lee SG, Kim CY, Cheong SA, Kim HY, Yu J, Kim K, Sung YH, Yoo HJ, Woo DC, Rho JK, Ha CH, Pack CG, Oh SH, Lim JS, Han YM, Hong EJ, Seong JK, Lee HW, Lee SW, Lee KU, Kim CJ, Nam SY, Cho YS, Baek IJ. Lee JG, et al. Nat Commun. 2024 Feb 19;15(1):1487. doi: 10.1038/s41467-024-45647-8. Nat Commun. 2024. PMID: 38374152 Free PMC article.
Proper placental development in early pregnancy ensures a positive outcome later on. The developmental relationship between the placenta and embryonic organs, such as the heart, is crucial for a normal pregnancy. However, the mechanism through which the placenta …
Proper placental development in early pregnancy ensures a positive outcome later on. The developmental relationship between the pl …
Human placental cholinergic system.
Sastry BV. Sastry BV. Biochem Pharmacol. 1997 Jun 1;53(11):1577-86. doi: 10.1016/s0006-2952(97)00017-8. Biochem Pharmacol. 1997. PMID: 9264309 Review.
However, there are many gaps in our knowledge, which include: (a) endogenous quaternary ammonium compounds other than ACh in human placental extracts; (b) the specificity of placental enzymes; (c) the subtypes and structures of placental muscarinic and …
However, there are many gaps in our knowledge, which include: (a) endogenous quaternary ammonium compounds other than ACh in human placen …
8,405 results