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Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing-remitting multiple sclerosis, the ProVal-MS study.
Bayas A, Mansmann U, Ön BI, Hoffmann VS, Berthele A, Mühlau M, Kowarik MC, Krumbholz M, Senel M, Steuerwald V, Naumann M, Hartberger J, Kerschensteiner M, Oswald E, Ruschil C, Ziemann U, Tumani H, Vardakas I, Albashiti F, Kramer F, Soto-Rey I, Spengler H, Mayer G, Kestler HA, Kohlbacher O, Hagedorn M, Boeker M, Kuhn K, Buchka S, Kohlmayer F, Kirschke JS, Behrens L, Zimmermann H, Bender B, Sollmann N, Havla J, Hemmer B; ProVal-MS study group. Bayas A, et al. Neurol Res Pract. 2024 Mar 7;6(1):15. doi: 10.1186/s42466-024-00310-x. Neurol Res Pract. 2024. PMID: 38449051 Free PMC article.
External validation of a multiple sclerosis treatment decision score using data from the ProVal-MS cohort study.
Buchka S, Hapfelmeier A, Kirschke JS, Steuerwald V, Naumann M, Soto-Rey I, Rohr SO, Kramer F, Behrens L, Oswald E, Kümpfel T, Zimmermann H, Hoffmann VS, Hagedorn M, Albashiti F, Krumbholz M, Ziemann U, Kohlbacher O, Sailer B, Braunmüller V, Biergans S, de Arruda Botelho Herr M, Ernemann U, Bürkle E, Bender B, Daul A, Ruff C, Römhild J, Wiestler B, Sepp D, Spengler H, Pallaoro P, Boeker M, Kohlmayer F, Dehmelt V, Berthele A, Mühlau M, Uibel P, Wauschkuhn J, Kuhn K, Senel M, Vardakas I, Taranu D, Kestler HA, Sollmann N, Irmak Ön B, Bilger S, Mansmann U, Bayas A, Havla J, Kowarik MC, Tumani H, Hemmer B; ProVal-MS Study Group. Buchka S, et al. Ther Adv Neurol Disord. 2025 Nov 21;18:17562864251391095. doi: 10.1177/17562864251391095. eCollection 2025. Ther Adv Neurol Disord. 2025. PMID: 41281704 Free PMC article.