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1982 1
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Page 1
Loss of Kmt2c or Kmt2d drives brain metastasis via KDM6A-dependent upregulation of MMP3.
Seehawer M, Li Z, Nishida J, Foidart P, Reiter AH, Rojas-Jimenez E, Goyette MA, Yan P, Raval S, Munoz Gomez M, Cejas P, Long HW, Papanastasiou M, Polyak K. Seehawer M, et al. Among authors: raval s. Nat Cell Biol. 2024 Jul;26(7):1165-1175. doi: 10.1038/s41556-024-01446-3. Epub 2024 Jun 26. Nat Cell Biol. 2024. PMID: 38926506 Free PMC article.
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial.
Weller M, Butowski N, Tran DD, Recht LD, Lim M, Hirte H, Ashby L, Mechtler L, Goldlust SA, Iwamoto F, Drappatz J, O'Rourke DM, Wong M, Hamilton MG, Finocchiaro G, Perry J, Wick W, Green J, He Y, Turner CD, Yellin MJ, Keler T, Davis TA, Stupp R, Sampson JH; ACT IV trial investigators. Weller M, et al. Lancet Oncol. 2017 Oct;18(10):1373-1385. doi: 10.1016/S1470-2045(17)30517-X. Epub 2017 Aug 23. Lancet Oncol. 2017. PMID: 28844499 Free article. Clinical Trial.
KDM4C inhibition blocks tumor growth in basal breast cancer by promoting cathepsin L-mediated histone H3 cleavage.
Li Z, Peluffo G, Stevens LE, Qiu X, Seehawer M, Tawawalla A, Huang XY, Egri SB, Raval S, McFadden M, D'Santos CS, Papachristou E, Kingston NL, Nishida J, Evans KE, Seo JH, Clement K, Temko D, Ekram M, Li R, Rees MG, Ronan MM, Roth JA, Simeonov A, Kales SC, Rai G, Lal-Nag M, Maloney DJ, Jadhav A, Michor F, Meissner A, Balko JM, Carroll JS, Freedman ML, Jaffe JD, Papanastasiou M, Long HW, Polyak K. Li Z, et al. Among authors: raval s. Nat Genet. 2025 Jun;57(6):1463-1477. doi: 10.1038/s41588-025-02197-z. Epub 2025 Jun 2. Nat Genet. 2025. PMID: 40457074 Free PMC article.
Author Correction: A substrate binding model for the KEOPS tRNA modifying complex.
Beenstock J, Ona SM, Porat J, Orlicky S, Wan LCK, Ceccarelli DF, Maisonneuve P, Szilard RK, Yin Z, Setiaputra D, Mao DYL, Khan M, Raval S, Schriemer DC, Bayfield MA, Durocher D, Sicheri F. Beenstock J, et al. Among authors: raval s. Nat Commun. 2025 May 22;16(1):4762. doi: 10.1038/s41467-025-60136-2. Nat Commun. 2025. PMID: 40404707 Free PMC article. No abstract available.
96 results