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Year Number of Results
1949 3
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2009 6
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44 results

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Page 1
Effect of adjuvant chemotherapy with fluorouracil plus folinic acid or gemcitabine vs observation on survival in patients with resected periampullary adenocarcinoma: the ESPAC-3 periampullary cancer randomized trial.
Neoptolemos JP, Moore MJ, Cox TF, Valle JW, Palmer DH, McDonald AC, Carter R, Tebbutt NC, Dervenis C, Smith D, Glimelius B, Charnley RM, Lacaine F, Scarfe AG, Middleton MR, Anthoney A, Ghaneh P, Halloran CM, Lerch MM, Oláh A, Rawcliffe CL, Verbeke CS, Campbell F, Büchler MW; European Study Group for Pancreatic Cancer. Neoptolemos JP, et al. JAMA. 2012 Jul 11;308(2):147-56. doi: 10.1001/jama.2012.7352. JAMA. 2012. PMID: 22782416 Clinical Trial.
Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety.
Goldring CE, Russomanno G, Pin C, Trairatphisan P, Beattie KA, Fisher CP, Piñero J, Brennan RJ, Clausznitzer D, Copple IM, de Kok TM, Duckworth CA, Furlong LI, Füzi B, Gabor A, Gall L, Hengstler J, Hermjakob H, Hunter F, Jennen D, Koskinen M, Kunnen SJ, Lammens L, Lobentanzer S, Mohr M, Passini E, Pritchard DM, Malik-Sheriff RS, Rodríguez B, Rossman EI, Saez-Rodríguez J, Schmidt F, Sison-Young R, Soininen I, Turner S, van de Water B, van Hasselt JGC, Venezia F, Willy JA, Leishman DJ, Stevens JL, Laplanche L. Goldring CE, et al. Among authors: rossman ei. Nat Rev Drug Discov. 2025 Oct 27. doi: 10.1038/s41573-025-01308-z. Online ahead of print. Nat Rev Drug Discov. 2025. PMID: 41145622 Review.
Improving the in Vivo QTc assay: The value of implementing best practices to support an integrated nonclinical-clinical QTc risk assessment and TQT substitute.
Vargas HM, Rossman EI, Wisialowski TA, Nichols J, Pugsley MK, Roche B, Gintant GA, Greiter-Wilke A, Kleiman RB, Valentin JP, Leishman DJ. Vargas HM, et al. Among authors: rossman ei. J Pharmacol Toxicol Methods. 2023 May-Jun;121:107265. doi: 10.1016/j.vascn.2023.107265. Epub 2023 Mar 28. J Pharmacol Toxicol Methods. 2023. PMID: 36997076 Free article. Review.
Sex-based differences in myocardial contractile reserve.
Petre RE, Quaile MP, Rossman EI, Ratcliffe SJ, Bailey BA, Houser SR, Margulies KB. Petre RE, et al. Among authors: rossman ei. Am J Physiol Regul Integr Comp Physiol. 2007 Feb;292(2):R810-8. doi: 10.1152/ajpregu.00377.2006. Epub 2006 Sep 28. Am J Physiol Regul Integr Comp Physiol. 2007. PMID: 17008460 Free article.
Current practices on the measurement of electrocardiogram and hemodynamic parameters in non-rodent species in regulatory safety assessment studies.
Valentin JP, Bourcier T, Chi X, Delaunois A, Foley CM, Henderson KA, Lainee P, Leishman DJ, Li D, Pawluk E, Pugsley MK, Rajamani S, Regan CP, Rolf MG, Ross R, Rossman EI, Tichenor SD, Villar IC, Wisialowski TA, Wu J, Vargas HM. Valentin JP, et al. Among authors: rossman ei. J Pharmacol Toxicol Methods. 2025 Sep;135:107765. doi: 10.1016/j.vascn.2025.107765. Epub 2025 Jun 19. J Pharmacol Toxicol Methods. 2025. PMID: 40543904
Improving the in vivo QTc assay: Nonclinical concentration-QTc modeling for risk assessment.
Wisialowski TA, Ether N, Foley CM, Kleiman R, Koshman Y, Leishman D, Martel E, Nichols JV, Popp J, Rajamani S, Riley S, Rossman EI, Vargas HM. Wisialowski TA, et al. Among authors: rossman ei. J Pharmacol Toxicol Methods. 2024 Jul-Aug;128:107515. doi: 10.1016/j.vascn.2024.107515. Epub 2024 May 20. J Pharmacol Toxicol Methods. 2024. PMID: 38777240 Free article. No abstract available.
A novel cardiovascular systems model to quantify drugs effects on the inter-relationship between contractility and other hemodynamic variables.
Fu Y, Taghvafard H, Said MM, Rossman EI, Collins TA, Billiald-Desquand S, Leishman D, van der Graaf PH, van Hasselt JGC, Snelder N. Fu Y, et al. Among authors: rossman ei. CPT Pharmacometrics Syst Pharmacol. 2022 May;11(5):640-652. doi: 10.1002/psp4.12774. Epub 2022 Mar 18. CPT Pharmacometrics Syst Pharmacol. 2022. PMID: 35213797 Free PMC article.
Blinded, Multicenter Evaluation of Drug-induced Changes in Contractility Using Human-induced Pluripotent Stem Cell-derived Cardiomyocytes.
Saleem U, van Meer BJ, Katili PA, Mohd Yusof NAN, Mannhardt I, Garcia AK, Tertoolen L, de Korte T, Vlaming MLH, McGlynn K, Nebel J, Bahinski A, Harris K, Rossman E, Xu X, Burton FL, Smith GL, Clements P, Mummery CL, Eschenhagen T, Hansen A, Denning C. Saleem U, et al. Among authors: rossman e. Toxicol Sci. 2020 Jul 1;176(1):103-123. doi: 10.1093/toxsci/kfaa058. Toxicol Sci. 2020. PMID: 32421822 Free PMC article.
Adjuvant chemotherapy with fluorouracil plus folinic acid vs gemcitabine following pancreatic cancer resection: a randomized controlled trial.
Neoptolemos JP, Stocken DD, Bassi C, Ghaneh P, Cunningham D, Goldstein D, Padbury R, Moore MJ, Gallinger S, Mariette C, Wente MN, Izbicki JR, Friess H, Lerch MM, Dervenis C, Oláh A, Butturini G, Doi R, Lind PA, Smith D, Valle JW, Palmer DH, Buckels JA, Thompson J, McKay CJ, Rawcliffe CL, Büchler MW; European Study Group for Pancreatic Cancer. Neoptolemos JP, et al. JAMA. 2010 Sep 8;304(10):1073-81. doi: 10.1001/jama.2010.1275. JAMA. 2010. PMID: 20823433 Clinical Trial.
44 results