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1912 1
1913 1
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1918 2
1919 1
1920 1
1924 1
1926 1
1928 4
1930 1
1931 1
1932 1
1933 2
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1941 4
1943 1
1945 1
1946 2
1947 3
1948 2
1949 2
1950 5
1951 4
1952 2
1953 4
1954 3
1955 7
1956 7
1957 5
1958 6
1959 4
1962 5
1963 13
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1965 26
1966 25
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1968 35
1969 54
1970 44
1971 42
1972 44
1973 49
1974 60
1975 319
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1984 640
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1986 672
1987 725
1988 723
1989 968
1990 941
1991 943
1992 972
1993 1020
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1995 1025
1996 1154
1997 1247
1998 1304
1999 1305
2000 1392
2001 1382
2002 1497
2003 1593
2004 1594
2005 1664
2006 1766
2007 1836
2008 2002
2009 1980
2010 2099
2011 2316
2012 2454
2013 2399
2014 2416
2015 2582
2016 2722
2017 3142
2018 3311
2019 3598
2020 4200
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2024 5228
2025 5988
2026 1748

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Page 1
Showing results for lowering v
Search for Rotering V instead (3 results)
Re-evaluation of the traditional diet-heart hypothesis: analysis of recovered data from Minnesota Coronary Experiment (1968-73).
Ramsden CE, Zamora D, Majchrzak-Hong S, Faurot KR, Broste SK, Frantz RP, Davis JM, Ringel A, Suchindran CM, Hibbeln JR. Ramsden CE, et al. BMJ. 2016 Apr 12;353:i1246. doi: 10.1136/bmj.i1246. BMJ. 2016. PMID: 27071971 Free PMC article.
Further, a systematic review and meta-analyses of randomized controlled trials that lowered serum cholesterol by providing vegetable oil rich in linoleic acid in place of saturated fat without confounding by concomitant interventions was conducted. ...CONCLUSIONS: Availabl …
Further, a systematic review and meta-analyses of randomized controlled trials that lowered serum cholesterol by providing vegetable …
The Li-ion rechargeable battery: a perspective.
Goodenough JB, Park KS. Goodenough JB, et al. J Am Chem Soc. 2013 Jan 30;135(4):1167-76. doi: 10.1021/ja3091438. Epub 2013 Jan 18. J Am Chem Soc. 2013. PMID: 23294028
The output on discharge is an external electronic current I at a voltage V for a time deltat. The chemical reaction of a rechargeable battery must be reversible on the application of a charging I and V. ...A passivating surface layer adds to the impedance of the Li( …
The output on discharge is an external electronic current I at a voltage V for a time deltat. The chemical reaction of a rechargeable …
Suppression of Huntington's Disease Somatic Instability by Transcriptional Repression and Direct CAG Repeat Binding.
Mathews EW, Coffey SR, Gärtner A, Belgrad J, Bragg RM, O'Reilly D, Cantle JP, McHugh C, Summers A, Fentz J, Schwagarus T, Cornelius A, Lingos I, Burch Z, Kovalenko M, Andrew MA, Frank Bennett C, Kordasiewicz HB, Marchionini DM, Wilkinson H, Vogt TF, Pinto RM, Khvorova A, Howland D, Wheeler VC, Carroll JB. Mathews EW, et al. bioRxiv [Preprint]. 2024 Nov 4:2024.11.04.619693. doi: 10.1101/2024.11.04.619693. bioRxiv. 2024. Update in: Nat Commun. 2025 Nov 14;16(1):10009. doi: 10.1038/s41467-025-64936-4. PMID: 39574582 Free PMC article. Updated. Preprint.
Thus, an attractive HD therapy would address both mHTT toxicity and SI, but to date the relationship between SI and HTT lowering remains unexplored. Here, we investigated multiple therapeutically-relevant HTT-lowering modalities to establish the relationship between …
Thus, an attractive HD therapy would address both mHTT toxicity and SI, but to date the relationship between SI and HTT lowering rema …
Beyond Lithium-Based Batteries.
Biemolt J, Jungbacker P, van Teijlingen T, Yan N, Rothenberg G. Biemolt J, et al. Materials (Basel). 2020 Jan 16;13(2):425. doi: 10.3390/ma13020425. Materials (Basel). 2020. PMID: 31963257 Free PMC article. Review.
The lower reactivity of magnesium makes pure Mg metal anodes much safer than alkali ones. ...Combining this with different cathodes gives good specific capacities, but with a lower voltage (<1.3 V, compared with 3.8 V for Li-ion batteries). Zinc has …
The lower reactivity of magnesium makes pure Mg metal anodes much safer than alkali ones. ...Combining this with different cathodes g …
Proprotein convertase 7 (PCSK7) reduces apoA-V levels.
Ashraf Y, Duval S, Sachan V, Essalmani R, Susan-Resiga D, Roubtsova A, Hamelin J, Gerhardy S, Kirchhofer D, Tagliabracci VS, Prat A, Kiss RS, Seidah NG. Ashraf Y, et al. FEBS J. 2020 Aug;287(16):3565-3578. doi: 10.1111/febs.15212. Epub 2020 Jan 29. FEBS J. 2020. PMID: 31945259 Free article.
Another PCSK7 SNP rs508487 is in linkage disequilibrium with a promoter variant of the liver-derived apolipoprotein A-V (apoA-V), an indirect activator of the lipoprotein lipase (LpL), and is associated with elevated TG levels. ...Co-expression of the phosphomimetic …
Another PCSK7 SNP rs508487 is in linkage disequilibrium with a promoter variant of the liver-derived apolipoprotein A-V (apoA-V …
Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates.
Frank-Kamenetsky M, Grefhorst A, Anderson NN, Racie TS, Bramlage B, Akinc A, Butler D, Charisse K, Dorkin R, Fan Y, Gamba-Vitalo C, Hadwiger P, Jayaraman M, John M, Jayaprakash KN, Maier M, Nechev L, Rajeev KG, Read T, Röhl I, Soutschek J, Tan P, Wong J, Wang G, Zimmermann T, de Fougerolles A, Vornlocher HP, Langer R, Anderson DG, Manoharan M, Koteliansky V, Horton JD, Fitzgerald K. Frank-Kamenetsky M, et al. Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11915-20. doi: 10.1073/pnas.0805434105. Epub 2008 Aug 11. Proc Natl Acad Sci U S A. 2008. PMID: 18695239 Free PMC article.
In NHP, a single dose of siRNA targeting PCSK9 resulted in a rapid, durable, and reversible lowering of plasma PCSK9, apolipoprotein B, and LDLc, without measurable effects on either HDL cholesterol (HDLc) or triglycerides (TGs). The effects of PCSK9 silencing lasted for 3 …
In NHP, a single dose of siRNA targeting PCSK9 resulted in a rapid, durable, and reversible lowering of plasma PCSK9, apolipoprotein …
Myoglobin deficiency impairs maximal oxygen uptake and exercise performance: a lesson from Mb-/- mice.
Zoladz JA, Grandys M, Smeda M, Kij A, Kurpinska A, Kwiatkowski G, Karasinski J, Hendgen-Cotta U, Chlopicki S, Majerczak J. Zoladz JA, et al. J Physiol. 2024 Mar;602(5):855-873. doi: 10.1113/JP285067. Epub 2024 Feb 20. J Physiol. 2024. PMID: 38376957 Free article.
V O2max expressed in ml min(-1) in Mb(-/) (-) mice was 37% lower than in Mb(+/+) mice (P < 0.001) and 13% lower when expressed in ml min(-1 ) kg body mass(-1) (P = 0.001). ...Our study showed that, contrary to recent suggestions, Mb deficiency significantl …
V O2max expressed in ml min(-1) in Mb(-/) (-) mice was 37% lower than in Mb(+/+) mice (P < 0.001) and 13% lower when …
An umbrella review of the association between dietary factors and hepatocellular carcinoma risk.
Li H, Cao QH, Liu H, Yan LJ, Ding ZN, Wang HC, Dong R, Tian BW, Han CL, Dong ZR, Yang LS, Mao XC, Yan YC, Wang DX, Li T. Li H, et al. Food Funct. 2025 May 19;16(10):3879-3890. doi: 10.1039/d4fo06165a. Food Funct. 2025. PMID: 40261056
The credibility of the evidence was assessed using the pre-specified evidence classification criteria, graded as convincing ("class I"), highly suggestive ("class II"), suggestive ("class III"), weak ("class IV"), or no evidence ("class V"). To evaluate the quality of evid …
The credibility of the evidence was assessed using the pre-specified evidence classification criteria, graded as convincing ("class I"), hig …
[Hypercalcemic crisis and hypocalcemic tetany].
Kasperk C. Kasperk C. Internist (Berl). 2017 Oct;58(10):1029-1036. doi: 10.1007/s00108-017-0311-3. Internist (Berl). 2017. PMID: 28835974 Review. German.
However, the primary goals in the treatment of HC include correcting dehydration and improving kidney function, lowering calcium levels and decreasing osteoclastic bone resorption. The goals are accomplished by volume repletion, forced diuresis, antiresorptive agents and h …
However, the primary goals in the treatment of HC include correcting dehydration and improving kidney function, lowering calcium leve …
Apolipoprotein A-V is a potential target for treating coronary artery disease: evidence from genetic and metabolomic analyses.
Ibi D, Boot M, Dollé MET, Jukema JW, Rosendaal FR, Christodoulides C, Neville MJ, Koivula R, Rensen PCN, Karpe F, Noordam R, Willems van Dijk K. Ibi D, et al. J Lipid Res. 2022 May;63(5):100193. doi: 10.1016/j.jlr.2022.100193. Epub 2022 Mar 10. J Lipid Res. 2022. PMID: 35278410 Free PMC article.
Triglyceride (TG)-lowering LPL variants in combination with genetic LDL-C-lowering variants are associated with reduced risk of coronary artery disease (CAD). ...Our results suggest that lower TG levels as a result of APOA5 variation have strong beneficial ef …
Triglyceride (TG)-lowering LPL variants in combination with genetic LDL-C-lowering variants are associated with reduced risk o …
85,279 results
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