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Page 1
Lymphodepletion - an essential but undervalued part of the chimeric antigen receptor T-cell therapy cycle.
Lickefett B, Chu L, Ortiz-Maldonado V, Warmuth L, Barba P, Doglio M, Henderson D, Hudecek M, Kremer A, Markman J, Nauerth M, Negre H, Sanges C, Staber PB, Tanzi R, Delgado J, Busch DH, Kuball J, Luu M, Jäger U. Lickefett B, et al. Among authors: sanges c. Front Immunol. 2023 Dec 22;14:1303935. doi: 10.3389/fimmu.2023.1303935. eCollection 2023. Front Immunol. 2023. PMID: 38187393 Free PMC article. Review.
European survey on CAR T-Cell analytical methods from apheresis to post-infusion immunomonitoring.
De Angelis B, D'Amore ML, Lecot P, Neininger K, Lorrain M, Gambotti L, Dreuillet C, Courcault E, Chatterjee S, Delgado J, Galy A, Franz P, Rodriguez-Madoz JR, Cabrerizo Y, Richter A, Girvalaki C, Noviello M, Tassi E, Sanges C, Luu M, Hudecek M, Kremer A, Locatelli F, Negre H, Quintarelli C. De Angelis B, et al. Among authors: sanges c. Front Immunol. 2025 Apr 24;16:1567582. doi: 10.3389/fimmu.2025.1567582. eCollection 2025. Front Immunol. 2025. PMID: 40342422 Free PMC article.
Virtual twins for personalised CAR T-cell therapy in myeloma.
Reiche K, Weirauch U, Kreuz M, Fischer L, Gras L, Neumuth T, Platzbecker U, Köhl U, Demlova R, Kremer A, Fröhlich H, Franke S, Merz M; CERTAINTY Consortium. Reiche K, et al. Lancet Haematol. 2025 Jul;12(7):e490-e491. doi: 10.1016/S2352-3026(25)00170-X. Lancet Haematol. 2025. PMID: 40610172 No abstract available.
Design specifications for biomedical virtual twins in engineered adoptive cellular immunotherapies.
Weirauch U, Kreuz M, Birkenbihl C, Alb M, Quaranta M, Calzone L, Orozco-Ruiz S, Binder S, Fischer L, Clavreul S, Maguri M, Ferle M, Rade M, Azarias G, Hydren JR, Jamarik J, Schwarz D, Sebestyen Z, Kuball J, Popp G, Antoine C, Knockaert M, Schoeder CT, Fandrei D, Sanges C, Radvilas V, Gagelmann N, Rückert M, Penack O, Fricke S, Schmidt A, Ward C, Steinbeisser C, Van Gyseghem JM, Niarakis A, Garderet L, Hudecek M, Neumuth T, Platzbecker U, Köhl U, Demlova R, Kremer A, Franke S, Fröhlich H, Merz M, Reiche K; CERTAINTY Consortium. Weirauch U, et al. Among authors: sanges c. NPJ Digit Med. 2025 Aug 1;8(1):493. doi: 10.1038/s41746-025-01809-6. NPJ Digit Med. 2025. PMID: 40750653 Free PMC article. Review.
Optimizing CAR-T treatment: A T2EVOLVE guide to raw and starting material selection.
Navarro S, Moukheiber C, Inogés Sancho S, Ruiz Guillén M, López-Díaz de Cerio A, Sanges C, Tanaka T, Arnould S, Briones J, Dolstra H, Hudecek M, Choudhary R, Schapitz I, Juan M, Worel N, Ammar D, Luu M, Müller M, Schroeder B, Negre H, Franz P. Navarro S, et al. Among authors: sanges c. Mol Ther. 2025 Mar 5;33(3):847-865. doi: 10.1016/j.ymthe.2024.11.017. Epub 2024 Nov 12. Mol Ther. 2025. PMID: 39533710 Free PMC article. Review.
Time to evolve: predicting engineered T cell-associated toxicity with next-generation models.
Donnadieu E, Luu M, Alb M, Anliker B, Arcangeli S, Bonini C, De Angelis B, Choudhary R, Espie D, Galy A, Holland C, Ivics Z, Kantari-Mimoun C, Kersten MJ, Köhl U, Kuhn C, Laugel B, Locatelli F, Marchiq I, Markman J, Moresco MA, Morris E, Negre H, Quintarelli C, Rade M, Reiche K, Renner M, Ruggiero E, Sanges C, Stauss H, Themeli M, Van den Brulle J, Hudecek M, Casucci M. Donnadieu E, et al. Among authors: sanges c. J Immunother Cancer. 2022 May;10(5):e003486. doi: 10.1136/jitc-2021-003486. J Immunother Cancer. 2022. PMID: 35577500 Free PMC article. Review.
Accelerating development of engineered T cell therapies in the EU: current regulatory framework for studying multiple product versions and T2EVOLVE recommendations.
Ammar D, Schapitz I, Luu M, Hudecek M, Meyer M, Taps T, Schröder B, Ivics Z, Sanges C, Franz P, Koehl U, Negre H, Johanna I, Awigena-Cook J. Ammar D, et al. Among authors: sanges c. Front Immunol. 2023 Nov 24;14:1280826. doi: 10.3389/fimmu.2023.1280826. eCollection 2023. Front Immunol. 2023. PMID: 38077331 Free PMC article. Review.
22 results