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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 1
1949 1
1955 2
1956 1
1957 1
1959 1
1960 1
1961 2
1962 1
1963 2
1964 4
1965 1
1966 1
1967 1
1968 3
1969 1
1970 3
1971 3
1972 6
1973 4
1974 2
1975 4
1976 9
1977 6
1978 9
1979 3
1980 4
1981 3
1982 3
1983 7
1984 1
1985 11
1986 11
1987 11
1988 6
1989 18
1990 10
1991 13
1992 12
1993 20
1994 25
1995 31
1996 28
1997 40
1998 38
1999 38
2000 27
2001 39
2002 41
2003 31
2004 32
2005 32
2006 28
2007 38
2008 47
2009 44
2010 47
2011 50
2012 61
2013 58
2014 81
2015 99
2016 116
2017 97
2018 88
2019 81
2020 97
2021 91
2022 83
2023 76
2024 89
2025 83

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1,882 results

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Page 1
A Secondary Injury Prevention Program May Decrease Contralateral Anterior Cruciate Ligament Injuries in Female Athletes: 2-Year Injury Rates in the ACL-SPORTS Randomized Controlled Trial.
Johnson JL, Capin JJ, Arundale AJH, Zarzycki R, Smith AH, Snyder-Mackler L. Johnson JL, et al. J Orthop Sports Phys Ther. 2020 Sep;50(9):523-530. doi: 10.2519/jospt.2020.9407. Epub 2020 Aug 1. J Orthop Sports Phys Ther. 2020. PMID: 32741328 Free PMC article. Clinical Trial.
Athletes were randomized to receive a training program of either progressive strengthening, agility, plyometrics, and prevention (SAPP) (n = 20) or SAPP plus perturbation training (n = 19); each had 10 sessions over 5 weeks. ...There was no statistically significant …
Athletes were randomized to receive a training program of either progressive strengthening, agility, plyometrics, and prevention (SAPP …
SAPP: functional genome annotation and analysis through a semantic framework using FAIR principles.
Koehorst JJ, van Dam JCJ, Saccenti E, Martins Dos Santos VAP, Suarez-Diez M, Schaap PJ. Koehorst JJ, et al. Bioinformatics. 2018 Apr 15;34(8):1401-1403. doi: 10.1093/bioinformatics/btx767. Bioinformatics. 2018. PMID: 29186322 Free PMC article.
This greatly reduces the administrative burden of handling multiple analysis tools and versions thereof and facilitates multi-level large scale comparative analysis. AVAILABILITY AND IMPLEMENTATION: SAPP is written in JAVA and freely available at https://gitlab.com/sapp …
This greatly reduces the administrative burden of handling multiple analysis tools and versions thereof and facilitates multi-level large sc …
SAPP: Structure Aware PTM Prediction.
Choo Y, Na S, Paek E. Choo Y, et al. Comput Biol Med. 2025 Oct 8;198(Pt A):111169. doi: 10.1016/j.compbiomed.2025.111169. Online ahead of print. Comput Biol Med. 2025. PMID: 41066820
Utilizing self-attention and cross-attention mechanisms, SAPP effectively captures complex interactions between sequences and their structural states, improving prediction accuracy and biological relevance over sequence-based models. Notably, SAPP is among the first …
Utilizing self-attention and cross-attention mechanisms, SAPP effectively captures complex interactions between sequences and their s …
Valproate in pregnancy: comment from the SAPP.
von Mandach U, Hösli I, Swiss Academy For Perinatal Pharmacology Sapp. von Mandach U, et al. Swiss Med Wkly. 2021 Feb 19;151:w20476. doi: 10.4414/smw.2021.20476. eCollection 2021 Feb 15. Swiss Med Wkly. 2021. PMID: 33641107 Free article. No abstract available.
Distinct roles of sAPP-alpha and sAPP-beta in regulating U251 cell differentiation.
Jiang J, Wang Y, Hou L, Fan L, Wang Q, Xu Z, Sun Q, Liu H. Jiang J, et al. Curr Alzheimer Res. 2013 Sep;10(7):706-13. doi: 10.2174/15672050113109990141. Curr Alzheimer Res. 2013. PMID: 23905992
However, the functions of the two types of sAPP are still unclear. We performed this study to compare the function of sAPP-alpha and sAPP-beta in differentiation of the glioma cell line U251. ...Furthermore, these findings suggest that new strategies, such as …
However, the functions of the two types of sAPP are still unclear. We performed this study to compare the function of sAPP-alp …
Rebuttal from Ryan M. Sapp and James M. Hagberg.
Sapp RM, Hagberg JM. Sapp RM, et al. J Physiol. 2018 Feb 15;596(4):547. doi: 10.1113/JP275554. Epub 2018 Jan 21. J Physiol. 2018. PMID: 29355956 Free PMC article. No abstract available.
Characterization and development of SAPP as a specific peptidic inhibitor that targets Porphyromonas gingivalis.
Ho MH, Lamont RJ, Chazin WJ, Chen H, Young DF, Kumar P, Xie H. Ho MH, et al. Mol Oral Microbiol. 2018 Dec;33(6):430-439. doi: 10.1111/omi.12246. Epub 2018 Oct 30. Mol Oral Microbiol. 2018. PMID: 30298683 Free PMC article.
This leads to a significant reduction in P gingivalis virulence potential, including its ability to colonize on the surface of Streptococcus gordonii, to invade human oral epithelial cells, and to produce gingipains. In this study, we showed that SAPP had minimal cytotoxic …
This leads to a significant reduction in P gingivalis virulence potential, including its ability to colonize on the surface of Streptococcus …
Secreted amyloid-β precursor protein functions as a GABABR1a ligand to modulate synaptic transmission.
Rice HC, de Malmazet D, Schreurs A, Frere S, Van Molle I, Volkov AN, Creemers E, Vertkin I, Nys J, Ranaivoson FM, Comoletti D, Savas JN, Remaut H, Balschun D, Wierda KD, Slutsky I, Farrow K, De Strooper B, de Wit J. Rice HC, et al. Science. 2019 Jan 11;363(6423):eaao4827. doi: 10.1126/science.aao4827. Science. 2019. PMID: 30630900 Free PMC article.
Accumulating evidence suggests that APP has a synaptic function mediated by an unidentified receptor for secreted APP (sAPP). Here we show that the sAPP extension domain directly bound the sushi 1 domain specific to the gamma-aminobutyric acid type B receptor subuni …
Accumulating evidence suggests that APP has a synaptic function mediated by an unidentified receptor for secreted APP (sAPP). Here we …
sAPP modulates iron efflux from brain microvascular endothelial cells by stabilizing the ferrous iron exporter ferroportin.
McCarthy RC, Park YH, Kosman DJ. McCarthy RC, et al. EMBO Rep. 2014 Jul;15(7):809-15. doi: 10.15252/embr.201338064. Epub 2014 May 27. EMBO Rep. 2014. PMID: 24867889 Free PMC article.
A sequence within the E2 domain of soluble amyloid precursor protein (sAPP) stimulates iron efflux. This activity has been attributed to a ferroxidase activity suggested for this motif. ...The data suggest that in stabilizing Fpn via the targeting due to the FTP sequence, …
A sequence within the E2 domain of soluble amyloid precursor protein (sAPP) stimulates iron efflux. This activity has been attributed …
1,882 results