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Page 1
ALS/FTD-linked TBK1 deficiency in microglia induces an aged-like microglial signature and drives social recognition deficits in mice.
Lenoel I, Ribon M, Lorenc F, Diebold A, Philibert CE, Robaldo D, Badsi M, Perronnet J, Lameth J, Berriat F, Misawa H, Coutelier M, Cassel R, Sarrazin N, Jost-Mousseau C, Bohl D, Millecamps S, Mallat M, Brenner D, Weishaupt JH, Boillée S, Lobsiger CS. Lenoel I, et al. Among authors: sarrazin n. Nat Commun. 2025 Aug 26;16(1):7951. doi: 10.1038/s41467-025-63211-w. Nat Commun. 2025. PMID: 40858618 Free PMC article.
Astrocyte-neuron combined targeting for CYP46A1 gene therapy in Huntington's disease.
Parsai LH, Chali F, Subashi E, Zeitouny C, Rey E, Berniard A, Bitton W, Urli L, Rousselot L, Sarrazin N, Blouin V, Den Dunnen WFA, Michaelsen-Preusse K, Korte M, Alves S, Cartier N. Parsai LH, et al. Among authors: sarrazin n. Acta Neuropathol Commun. 2025 Aug 26;13(1):184. doi: 10.1186/s40478-025-02054-4. Acta Neuropathol Commun. 2025. PMID: 40859407 Free PMC article.
P2X7-deficiency improves plasticity and cognitive abilities in a mouse model of Tauopathy.
Carvalho K, Martin E, Ces A, Sarrazin N, Lagouge-Roussey P, Nous C, Boucherit L, Youssef I, Prigent A, Faivre E, Eddarkaoui S, Gauvrit T, Vieau D, Boluda S, Huin V, Fontaine B, Buée L, Delatour B, Dutar P, Sennlaub F, Guillonneau X, Blum D, Delarasse C; NeuroCEB Brain Bank. Carvalho K, et al. Among authors: sarrazin n. Prog Neurobiol. 2021 Nov;206:102139. doi: 10.1016/j.pneurobio.2021.102139. Epub 2021 Aug 12. Prog Neurobiol. 2021. PMID: 34391810 Free article.
Failed remyelination of the nonhuman primate optic nerve leads to axon degeneration, retinal damages, and visual dysfunction.
Sarrazin N, Chavret-Reculon E, Bachelin C, Felfli M, Arab R, Gilardeau S, Brazhnikova E, Dubus E, Yaha-Cherif L, Lorenceau J, Picaud S, Rosolen S, Moissonnier P, Pouget P, Baron-Van Evercooren A. Sarrazin N, et al. Proc Natl Acad Sci U S A. 2022 Mar 8;119(10):e2115973119. doi: 10.1073/pnas.2115973119. Epub 2022 Mar 2. Proc Natl Acad Sci U S A. 2022. PMID: 35235463 Free PMC article.
Adaptive human immunity drives remyelination in a mouse model of demyelination.
El Behi M, Sanson C, Bachelin C, Guillot-Noël L, Fransson J, Stankoff B, Maillart E, Sarrazin N, Guillemot V, Abdi H, Cournu-Rebeix I, Fontaine B, Zujovic V. El Behi M, et al. Among authors: sarrazin n. Brain. 2017 Apr 1;140(4):967-980. doi: 10.1093/brain/awx008. Brain. 2017. PMID: 28334918 Free PMC article.
15 results