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66 results

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Page 1
Safety and efficacy of the ChAdOx1 nCoV-19 vaccine (AZD1222) against SARS-CoV-2: an interim analysis of four randomised controlled trials in Brazil, South Africa, and the UK.
Voysey M, Clemens SAC, Madhi SA, Weckx LY, Folegatti PM, Aley PK, Angus B, Baillie VL, Barnabas SL, Bhorat QE, Bibi S, Briner C, Cicconi P, Collins AM, Colin-Jones R, Cutland CL, Darton TC, Dheda K, Duncan CJA, Emary KRW, Ewer KJ, Fairlie L, Faust SN, Feng S, Ferreira DM, Finn A, Goodman AL, Green CM, Green CA, Heath PT, Hill C, Hill H, Hirsch I, Hodgson SHC, Izu A, Jackson S, Jenkin D, Joe CCD, Kerridge S, Koen A, Kwatra G, Lazarus R, Lawrie AM, Lelliott A, Libri V, Lillie PJ, Mallory R, Mendes AVA, Milan EP, Minassian AM, McGregor A, Morrison H, Mujadidi YF, Nana A, O'Reilly PJ, Padayachee SD, Pittella A, Plested E, Pollock KM, Ramasamy MN, Rhead S, Schwarzbold AV, Singh N, Smith A, Song R, Snape MD, Sprinz E, Sutherland RK, Tarrant R, Thomson EC, Török ME, Toshner M, Turner DPJ, Vekemans J, Villafana TL, Watson MEE, Williams CJ, Douglas AD, Hill AVS, Lambe T, Gilbert SC, Pollard AJ; Oxford COVID Vaccine Trial Group. Voysey M, et al. Lancet. 2021 Jan 9;397(10269):99-111. doi: 10.1016/S0140-6736(20)32661-1. Epub 2020 Dec 8. Lancet. 2021. PMID: 33306989 Free PMC article. Clinical Trial.
Early mucosal responses following a randomised controlled human inhaled infection with attenuated Mycobacterium bovis BCG.
Marshall JL, Satti I, Surakhy M, Harris SA, Morrison H, Wittenberg RE, Peralta Alvarez MP, Li S, Lopez Ramon R, Hoogkamer E, Salguero FJ, Ramos Lopez F, Mitton C, Cabrera Puig I, Powell Doherty R, Tanner R, Hinks TSC, Bettinson H, McShane H. Marshall JL, et al. Among authors: satti i. Nat Commun. 2025 May 29;16(1):4989. doi: 10.1038/s41467-025-60285-4. Nat Commun. 2025. PMID: 40442144 Free PMC article. Clinical Trial.
Intravenous BCG vaccination in non-human primates induces superior serum antibody titers with enhanced avidity and opsonizing capacity compared to the intradermal route.
Peralta Alvarez MP, Downward K, White A, Harris SA, Satti I, Li S, Morrison A, Sibley L, Sarfas C, Dennis M, Azema HR, Sharpe S, McShane H, Tanner R. Peralta Alvarez MP, et al. Among authors: satti i. Vaccine. 2024 Dec 2;42(26):126444. doi: 10.1016/j.vaccine.2024.126444. Epub 2024 Nov 10. Vaccine. 2024. PMID: 39522337 Free PMC article.
MetE: a promising protective antigen for tuberculosis vaccine development.
Almujri SS, Stylianou E, Nicastri A, Satti I, Korompis M, Li S, De Voss CJ, Polo Peralta Alvarez M, Tanner R, Bettencourt PJG, Ternette N, McShane H. Almujri SS, et al. Among authors: satti i. Front Immunol. 2025 Jul 21;16:1593263. doi: 10.3389/fimmu.2025.1593263. eCollection 2025. Front Immunol. 2025. PMID: 40761798 Free PMC article.
TBVAC2020: Advancing Tuberculosis Vaccines from Discovery to Clinical Development.
Kaufmann SHE, Dockrell HM, Drager N, Ho MM, McShane H, Neyrolles O, Ottenhoff THM, Patel B, Roordink D, Spertini F, Stenger S, Thole J, Verreck FAW, Williams A; TBVAC2020 Consortium. Kaufmann SHE, et al. Front Immunol. 2017 Oct 4;8:1203. doi: 10.3389/fimmu.2017.01203. eCollection 2017. Front Immunol. 2017. PMID: 29046674 Free PMC article. Review.
A dose escalation study to evaluate the safety of an aerosol BCG infection in previously BCG-vaccinated healthy human UK adults.
Fredsgaard-Jones T, Harris SA, Morrison H, Ateere A, Nassanga B, Ramon RL, Mitton C, Fletcher E, Decker J, Preston-Jones H, Jackson S, Mawer A, Satti I, Barer M, Hinks T, Bettinson H, McShane H. Fredsgaard-Jones T, et al. Among authors: satti i. Front Immunol. 2024 Nov 14;15:1427371. doi: 10.3389/fimmu.2024.1427371. eCollection 2024. Front Immunol. 2024. PMID: 39611145 Free PMC article. Clinical Trial.
Phase I Trial Evaluating the Safety and Immunogenicity of Candidate TB Vaccine MVA85A, Delivered by Aerosol to Healthy M.tb-Infected Adults.
Riste M, Marshall JL, Satti I, Harris SA, Wilkie M, Lopez Ramon R, Wright D, Wittenberg RE, Vermaak S, Powell Doherty R, Lawrie A, Conlon CP, Cosgrove C, Gleeson F, Lipman M, Moss P, Perrin F, Dedicoat M, Bettinson H, McShane H. Riste M, et al. Among authors: satti i. Vaccines (Basel). 2021 Apr 16;9(4):396. doi: 10.3390/vaccines9040396. Vaccines (Basel). 2021. PMID: 33923628 Free PMC article.
A phase I trial evaluating the safety and immunogenicity of a candidate tuberculosis vaccination regimen, ChAdOx1 85A prime - MVA85A boost in healthy UK adults.
Wilkie M, Satti I, Minhinnick A, Harris S, Riste M, Ramon RL, Sheehan S, Thomas ZM, Wright D, Stockdale L, Hamidi A, O'Shea MK, Dwivedi K, Behrens HM, Davenne T, Morton J, Vermaak S, Lawrie A, Moss P, McShane H. Wilkie M, et al. Among authors: satti i. Vaccine. 2020 Jan 22;38(4):779-789. doi: 10.1016/j.vaccine.2019.10.102. Epub 2019 Nov 15. Vaccine. 2020. PMID: 31735500 Free PMC article. Clinical Trial.
66 results