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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1951 2
1955 1
1956 4
1957 2
1958 1
1963 2
1964 1
1965 1
1966 3
1967 5
1968 7
1969 4
1970 3
1971 9
1972 10
1973 7
1974 7
1975 9
1976 6
1977 10
1978 12
1979 21
1980 9
1981 11
1982 10
1983 20
1984 12
1985 19
1986 17
1987 21
1988 28
1989 17
1990 17
1991 16
1992 17
1993 13
1994 11
1995 9
1996 7
1997 10
1998 12
1999 10
2000 10
2001 16
2002 15
2003 20
2004 28
2005 14
2006 15
2007 16
2008 15
2009 26
2010 33
2011 27
2012 21
2013 24
2014 31
2015 30
2016 33
2017 22
2018 27
2019 42
2020 28
2021 31
2022 27
2023 29
2024 40
2025 33

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1,012 results

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Page 1
Rubisco Function, Evolution, and Engineering.
Prywes N, Phillips NR, Tuck OT, Valentin-Alvarado LE, Savage DF. Prywes N, et al. Among authors: savage df. Annu Rev Biochem. 2023 Jun 20;92:385-410. doi: 10.1146/annurev-biochem-040320-101244. Epub 2023 Apr 26. Annu Rev Biochem. 2023. PMID: 37127263 Free article. Review.
GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans.
Patel S, Alvarez-Guaita A, Melvin A, Rimmington D, Dattilo A, Miedzybrodzka EL, Cimino I, Maurin AC, Roberts GP, Meek CL, Virtue S, Sparks LM, Parsons SA, Redman LM, Bray GA, Liou AP, Woods RM, Parry SA, Jeppesen PB, Kolnes AJ, Harding HP, Ron D, Vidal-Puig A, Reimann F, Gribble FM, Hulston CJ, Farooqi IS, Fafournoux P, Smith SR, Jensen J, Breen D, Wu Z, Zhang BB, Coll AP, Savage DB, O'Rahilly S. Patel S, et al. Among authors: savage db. Cell Metab. 2019 Mar 5;29(3):707-718.e8. doi: 10.1016/j.cmet.2018.12.016. Epub 2019 Jan 10. Cell Metab. 2019. PMID: 30639358 Free PMC article.
Mutational scanning of TnpB reveals latent activity for genome editing.
Thornton BW, Weissman RF, Rodriguez JE, Tran RV, Duong BT, Terrace CI, Nagalakshmi U, Austin G, Groover ED, Wang FZ, Park JU, Georgieva V, Tartaglia J, Cho MJ, Dinesh-Kumar SP, Doudna JA, Savage DF. Thornton BW, et al. Among authors: savage df. bioRxiv [Preprint]. 2025 Oct 30:2025.02.11.637750. doi: 10.1101/2025.02.11.637750. bioRxiv. 2025. PMID: 39990302 Free PMC article. Preprint.
GDF15 mediates the effects of metformin on body weight and energy balance.
Coll AP, Chen M, Taskar P, Rimmington D, Patel S, Tadross JA, Cimino I, Yang M, Welsh P, Virtue S, Goldspink DA, Miedzybrodzka EL, Konopka AR, Esponda RR, Huang JT, Tung YCL, Rodriguez-Cuenca S, Tomaz RA, Harding HP, Melvin A, Yeo GSH, Preiss D, Vidal-Puig A, Vallier L, Nair KS, Wareham NJ, Ron D, Gribble FM, Reimann F, Sattar N, Savage DB, Allan BB, O'Rahilly S. Coll AP, et al. Among authors: savage db. Nature. 2020 Feb;578(7795):444-448. doi: 10.1038/s41586-019-1911-y. Epub 2019 Dec 25. Nature. 2020. PMID: 31875646 Free PMC article. Clinical Trial.
Accelerated RNA detection using tandem CRISPR nucleases.
Liu TY, Knott GJ, Smock DCJ, Desmarais JJ, Son S, Bhuiya A, Jakhanwal S, Prywes N, Agrawal S, Díaz de León Derby M, Switz NA, Armstrong M, Harris AR, Charles EJ, Thornton BW, Fozouni P, Shu J, Stephens SI, Kumar GR, Zhao C, Mok A, Iavarone AT, Escajeda AM, McIntosh R, Kim S, Dugan EJ; IGI Testing Consortium; Pollard KS, Tan MX, Ott M, Fletcher DA, Lareau LF, Hsu PD, Savage DF, Doudna JA. Liu TY, et al. Among authors: savage df. Nat Chem Biol. 2021 Sep;17(9):982-988. doi: 10.1038/s41589-021-00842-2. Epub 2021 Aug 5. Nat Chem Biol. 2021. PMID: 34354262 Free PMC article.
Somatic loss-of-function mutations in CIDEB reduce hepatic steatosis by increasing lipolysis and fatty acid oxidation.
Zeng Q, Patel S, Wang X, Hsieh MH, Li Z, Ren X, Wang J, Kim D, Li S, Gu X, Mannino G, Maggiore G, Fang X, Li L, Zhu M, Wang M, Li B, Bellary A, Lim K, Qi Z, Pushpa P, Mandour MO, Saudek V, Sharma T, Zhang Y, Hoxhaj G, Mishra P, Gopal P, Campbell P, Hoare M, Savage DB, Zhu H. Zeng Q, et al. Among authors: savage db. J Hepatol. 2025 Jul 4:S0168-8278(25)02320-7. doi: 10.1016/j.jhep.2025.06.021. Online ahead of print. J Hepatol. 2025. PMID: 40618957 Free PMC article.
Recent developments in lipodystrophy.
Melvin A, Stears A, Savage DB. Melvin A, et al. Among authors: savage db. Curr Opin Lipidol. 2019 Aug;30(4):284-290. doi: 10.1097/MOL.0000000000000613. Curr Opin Lipidol. 2019. PMID: 31135595 Review.
Loss of Mfn1 but not Mfn2 enhances adipogenesis.
Mann JP, Tábara LC, Patel S, Pushpa P, Alvarez-Guaita A, Dong L, Haider A, Lim K, Tandon P, Scurria F, Minchin JEN, O'Rahilly S S, Fazakerley DJ, Prudent J, Semple RK, Savage DB. Mann JP, et al. Among authors: savage db. PLoS One. 2024 Dec 31;19(12):e0306243. doi: 10.1371/journal.pone.0306243. eCollection 2024. PLoS One. 2024. PMID: 39739772 Free PMC article.
1,012 results