Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1991 2
1995 1
1997 3
1999 3
2000 2
2001 6
2002 2
2003 4
2004 1
2005 3
2006 9
2007 7
2008 5
2009 9
2010 5
2011 2
2012 2
2013 3
2014 4
2015 7
2016 8
2017 3
2018 2
2019 6
2020 9
2021 7
2022 8
2023 6
2024 4
2025 6

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

123 results

Results by year

Filters applied: . Clear all
Page 1
A human genome editing-based MLL::AF4 ALL model recapitulates key cellular and molecular leukemogenic features.
Bueno C, Torres-Ruiz R, Velasco-Hernandez T, Molina O, Petazzi P, Martinez A, Rodriguez V, Vinyoles M, Cantilena S, Williams O, Vega-Garcia N, Rodriguez-Perales S, Segovia JC, Quintana-Bustamante O, Roy A, Meyer C, Marschalek R, Smith AL, Milne TA, Fraga MF, Tejedor JR, Menéndez P. Bueno C, et al. Among authors: segovia jc. Blood. 2023 Nov 16;142(20):1752-1756. doi: 10.1182/blood.2023020858. Blood. 2023. PMID: 37756522 Free article.
Haematopoietic gene therapy of non-conditioned patients with Fanconi anaemia-A: results from open-label phase 1/2 (FANCOLEN-1) and long-term clinical trials.
Río P, Zubicaray J, Navarro S, Gálvez E, Sánchez-Domínguez R, Nicoletti E, Sebastián E, Rothe M, Pujol R, Bogliolo M, John-Neek P, Bastone AL, Schambach A, Wang W, Schmidt M, Larcher L, Segovia JC, Yáñez RM, Alberquilla O, Díez B, Fernández-García M, García-García L, Ramírez M, Galy A, Lefrere F, Cavazzana M, Leblanc T, García de Andoin N, López-Almaraz R, Catalá A, Barquinero J, Rodríguez-Perales S, Rao G, Surrallés J, Soulier J, Díaz-de-Heredia C, Schwartz JD, Sevilla J, Bueren JA; FANCOLEN-1 gene therapy investigators. Río P, et al. Among authors: segovia jc. Lancet. 2025 Dec 21;404(10471):2584-2592. doi: 10.1016/S0140-6736(24)01880-4. Epub 2024 Dec 3. Lancet. 2025. PMID: 39642902 Clinical Trial.
Lentivirus-mediated gene therapy corrects ribosomal biogenesis and shows promise for Diamond Blackfan anemia.
Giménez Y, Palacios M, Sánchez-Domínguez R, Zorbas C, Peral J, Puzik A, Ugalde L, Alberquilla O, Villanueva M, Río P, Gálvez E, Da Costa L, Strullu M, Catala A, Ruiz-Llobet A, Segovia JC, Sevilla J, Strahm B, Niemeyer CM, Beléndez C, Leblanc T, Lafontaine DL, Bueren J, Navarro S. Giménez Y, et al. Among authors: segovia jc. JCI Insight. 2024 May 22;9(10):e171650. doi: 10.1172/jci.insight.171650. JCI Insight. 2024. PMID: 38775150 Free PMC article.
Gene Editing for Inherited Red Blood Cell Diseases.
Quintana-Bustamante O, Fañanas-Baquero S, Dessy-Rodriguez M, Ojeda-Pérez I, Segovia JC. Quintana-Bustamante O, et al. Among authors: segovia jc. Front Physiol. 2022 Mar 28;13:848261. doi: 10.3389/fphys.2022.848261. eCollection 2022. Front Physiol. 2022. PMID: 35418876 Free PMC article. Review.
Advances in the gene therapy of monogenic blood cell diseases.
Bueren JA, Quintana-Bustamante O, Almarza E, Navarro S, Río P, Segovia JC, Guenechea G. Bueren JA, et al. Among authors: segovia jc. Clin Genet. 2020 Jan;97(1):89-102. doi: 10.1111/cge.13593. Epub 2019 Jul 11. Clin Genet. 2020. PMID: 31231794 Review.
GPR41 and GPR43 modulate rodent pancreatic α-cell function and growth.
Sánchez-Roncero A, Fernández-Marcelo T, Pérez-Serna AA, Martínez-Oca P, Alberquilla-Fernández O, Sánchez-Domínguez R, Segovia JC, Escrivá F, Gálvez BG, Álvarez C, Marroqui L, Fernández-Millán E. Sánchez-Roncero A, et al. Among authors: segovia jc. Life Sci. 2025 Oct 15;379:123913. doi: 10.1016/j.lfs.2025.123913. Epub 2025 Aug 14. Life Sci. 2025. PMID: 40818660 Free article.
Mitapivat versus Placebo for Pyruvate Kinase Deficiency.
Shah AJ, Schwartz JD, Segovia JC. Shah AJ, et al. Among authors: segovia jc. N Engl J Med. 2022 Jun 30;386(26):2538-2539. doi: 10.1056/NEJMc2206275. N Engl J Med. 2022. PMID: 35767453 No abstract available.
Soluble mutant huntingtin drives early human pathogenesis in Huntington's disease.
Miguez A, Gomis C, Vila C, Monguió-Tortajada M, Fernández-García S, Bombau G, Galofré M, García-Bravo M, Sanders P, Fernández-Medina H, Poquet B, Salado-Manzano C, Roura S, Alberch J, Segovia JC, Allen ND, Borràs FE, Canals JM. Miguez A, et al. Among authors: segovia jc. Cell Mol Life Sci. 2023 Aug 3;80(8):238. doi: 10.1007/s00018-023-04882-w. Cell Mol Life Sci. 2023. PMID: 37535170 Free PMC article.
Mutations in the RACGAP1 gene cause autosomal recessive congenital dyserythropoietic anemia type III.
Hernández G, Romero-Cortadellas L, Ferrer-Cortès X, Venturi V, Dessy-Rodriguez M, Olivella M, Husami A, De Soto CP, Morales-Camacho RM, Villegas A, González-Fernández FA, Morado M, Kalfa TA, Quintana-Bustamante O, Pérez-Montero S, Tornador C, Segovia JC, Sánchez M. Hernández G, et al. Among authors: segovia jc. Haematologica. 2023 Feb 1;108(2):581-587. doi: 10.3324/haematol.2022.281277. Haematologica. 2023. PMID: 36200420 Free PMC article. No abstract available.
Who should be eligible for gene therapy clinical trials in red blood cell pyruvate kinase deficiency (PKD)?: Toward an expanded definition of severe PKD.
Schwartz JD, Barcellini W, Grace RF, Bianchi P, Zanella A, López Lorenzo JL, Sevilla J, Shah AJ, Glader B, Nicoletti E, Navarro Ordoñez S, Segovia JC. Schwartz JD, et al. Among authors: segovia jc. Am J Hematol. 2022 Mar 1;97(3):E120-E125. doi: 10.1002/ajh.26458. Epub 2022 Jan 24. Am J Hematol. 2022. PMID: 34989415 Free PMC article. Review. No abstract available.
123 results