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. 2023 May 24;76(10):1847-1849.
doi: 10.1093/cid/ciad029.

Transmission of Mycobacterium tuberculosis to Healthcare Personnel Resulting From Contaminated Bone Graft Material, United States, June 2021-August 2022

Collaborators, Affiliations

Transmission of Mycobacterium tuberculosis to Healthcare Personnel Resulting From Contaminated Bone Graft Material, United States, June 2021-August 2022

Ruoran Li et al. Clin Infect Dis. .

Abstract

A nationwide tuberculosis outbreak linked to a viable bone allograft product contaminated with Mycobacterium tuberculosis was identified in June 2021. Our subsequent investigation identified 73 healthcare personnel with new latent tuberculosis infection following exposure to the contaminated product, product recipients, surgical instruments, or medical waste.

Keywords: bone transplantation; contact investigation; healthcare-associated infections; surgical procedures; tuberculosis.

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Conflict of interest statement

Potential conflicts of interest. All authors: No reported conflicts of interest. All authors have submitted the ICMJE Form for Disclosure of Potential Conflicts of Interest. Conflicts that the editors consider relevant to the content of the manuscript have been disclosed.

References

    1. Li R, Wilson WW, Schwartz NG, et al. Notes from the field: tuberculosis outbreak linked to a contaminated bone graft product used in spinal surgery—Delaware, March-June 2021. MMWR Morb Mortal Wkly Rep 2021; 70:1261–3. - PMC - PubMed
    1. Schwartz N, Hernandez-Romieu A, Annambhotla P, et al. Nationwide tuberculosis outbreak in the United States linked to a bone graft product: an outbreak report Lancet Infect Dis 2022; In press. 10.1016/S1473-3099(22)00425-X - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention. TB infection control in healthcare settings. Available at: https://www.cdc.gov/mmwr/preview/mmwrhtml/rr5417al.htm?s_cid=rr5417al_e. Accessed 30 January 2023.
    1. Frampton MW. An outbreak of tuberculosis among hospital personnel caring for a patient with a skin ulcer. Ann Intern Med 1992; 117:312–3. - PubMed
    1. Keijman J, Tjhie J, Olde Damink S, Alink M. Unusual nosocomial transmission of Mycobacterium tuberculosis. Eur J Clin Microbiol Infect Dis 2001; 20:808–9. - PubMed