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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1956 1
1957 2
1959 2
1961 2
1962 3
1963 2
1964 1
1965 3
1967 3
1968 3
1969 4
1970 1
1971 1
1972 2
1973 2
1975 2
1976 1
1977 2
1978 2
1979 2
1980 2
1981 1
1982 2
1983 2
1984 3
1986 2
1987 3
1988 3
1989 4
1990 8
1991 7
1992 3
1993 2
1994 1
1995 8
1996 6
1997 9
1998 8
1999 6
2000 11
2001 13
2002 5
2003 13
2004 17
2005 16
2006 22
2007 30
2008 17
2009 31
2010 30
2011 33
2012 41
2013 38
2014 30
2015 38
2016 42
2017 43
2018 41
2019 43
2020 53
2021 42
2022 43
2023 42
2024 25
2025 20

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791 results

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Page 1
Patient-Specific In Vivo Gene Editing to Treat a Rare Genetic Disease.
Musunuru K, Grandinette SA, Wang X, Hudson TR, Briseno K, Berry AM, Hacker JL, Hsu A, Silverstein RA, Hille LT, Ogul AN, Robinson-Garvin NA, Small JC, McCague S, Burke SM, Wright CM, Bick S, Indurthi V, Sharma S, Jepperson M, Vakulskas CA, Collingwood M, Keogh K, Jacobi A, Sturgeon M, Brommel C, Schmaljohn E, Kurgan G, Osborne T, Zhang H, Kinney K, Rettig G, Barbosa CJ, Semple SC, Tam YK, Lutz C, George LA, Kleinstiver BP, Liu DR, Ng K, Kassim SH, Giannikopoulos P, Alameh MG, Urnov FD, Ahrens-Nicklas RC. Musunuru K, et al. Among authors: semple sc. N Engl J Med. 2025 Jun 12;392(22):2235-2243. doi: 10.1056/NEJMoa2504747. Epub 2025 May 15. N Engl J Med. 2025. PMID: 40373211
The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs.
Akinc A, Maier MA, Manoharan M, Fitzgerald K, Jayaraman M, Barros S, Ansell S, Du X, Hope MJ, Madden TD, Mui BL, Semple SC, Tam YK, Ciufolini M, Witzigmann D, Kulkarni JA, van der Meel R, Cullis PR. Akinc A, et al. Among authors: semple sc. Nat Nanotechnol. 2019 Dec;14(12):1084-1087. doi: 10.1038/s41565-019-0591-y. Nat Nanotechnol. 2019. PMID: 31802031 No abstract available.
Systemic delivery of biotherapeutic RNA to the myocardium transiently modulates cardiac contractility in vivo.
Shuvaev VV, Tam YK, Lee BW, Myerson JW, Herbst A, Kiseleva RY, Glassman PM, Parhiz H, Alameh MG, Pardi N, Muramatsu H, Shuvaeva TI, Arguiri E, Marcos-Contreras OA, Hood ED, Brysgel TV, Nong J, Papp TE, Eaton DM, Riley R, Palanki R, Musunuru K, Brenner JS, Mitchell MJ, Ferrari VA, Mui BL, Semple SC, Weppler SA, Atluri P, Margulies KB, Weissman D, Muzykantov VR. Shuvaev VV, et al. Among authors: semple sc. Proc Natl Acad Sci U S A. 2025 Jul 22;122(29):e2409266122. doi: 10.1073/pnas.2409266122. Epub 2025 Jul 16. Proc Natl Acad Sci U S A. 2025. PMID: 40668829
Linguistic laws in biology.
Semple S, Ferrer-I-Cancho R, Gustison ML. Semple S, et al. Trends Ecol Evol. 2022 Jan;37(1):53-66. doi: 10.1016/j.tree.2021.08.012. Epub 2021 Sep 28. Trends Ecol Evol. 2022. PMID: 34598817 Free PMC article. Review.
Autologous macrophage therapy for liver cirrhosis: a phase 2 open-label randomized controlled trial.
Brennan PN, MacMillan M, Manship T, Moroni F, Glover A, Troland D, MacPherson I, Graham C, Aird R, Semple SIK, Morris DM, Fraser AR, Pass C, McGowan NWA, Turner ML, Manson L, Lachlan NJ, Dillon JF, Kilpatrick AM, Campbell JDM, Fallowfield JA, Forbes SJ. Brennan PN, et al. Among authors: semple sik. Nat Med. 2025 Mar;31(3):979-987. doi: 10.1038/s41591-024-03406-8. Epub 2025 Jan 10. Nat Med. 2025. PMID: 39794616 Free PMC article. Clinical Trial.
Manganese-enhanced MRI of the myocardium.
Spath NB, Thompson G, Baker AH, Dweck MR, Newby DE, Semple SIK. Spath NB, et al. Among authors: semple sik. Heart. 2019 Nov;105(22):1695-1700. doi: 10.1136/heartjnl-2019-315227. Epub 2019 Jul 23. Heart. 2019. PMID: 31337670 Free PMC article. Review.
791 results