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Year Number of Results
1992 2
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2011 10
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203 results

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Page 1
Preferential Synaptic Type of GABA-A Receptor Ligands Enhancing Neuronal Survival and Facilitating Functional Recovery After Ischemic Stroke.
Mordyl B, Fajkis-Zajączkowska N, Szafrańska K, Siwek A, Głuch-Lutwin M, Żmudzki P, Jończyk J, Karcz T, Słoczyńska K, Pękala E, Pomierny B, Krzyżanowska W, Jurczyk J, Skórkowska A, Sałach A, Jastrzębska-Więsek M, Walczak M, Gawlik MT, Smolik M, Kolaczkowski M, Marcinkowska M. Mordyl B, et al. Among authors: siwek a. J Med Chem. 2024 Dec 26;67(24):21859-21889. doi: 10.1021/acs.jmedchem.4c01578. Epub 2024 Dec 12. J Med Chem. 2024. PMID: 39668673
Contilisant+Tubastatin A Hybrids: Polyfunctionalized Indole Derivatives as New HDAC Inhibitor-Based Multitarget Small Molecules with In Vitro and In Vivo Activity in Neurodegenerative Diseases.
Toledano-Pinedo M, Porro-Pérez A, Schäker-Hübner L, Romero F, Dong M, Samadi A, Almendros P, Iriepa I, Bautista-Aguilera ÒM, Rodríguez-Fernández MM, Solana-Manrique C, Sanchis I, Mora-Morell A, Rodrìguez AC, Sànchez-Pérez AM, Knez D, Gobec S, Bellver-Sanchis A, Pérez B, Dobrydnev AV, Artetxe-Zurutuza A, Matheu A, Siwek A, Wolak M, Satała G, Bojarski AJ, Doroz-Płonka A, Handzlik J, Godyń J, Więckowska A, Paricio N, Griñán-Ferré C, Hansen FK, Marco-Contelles J. Toledano-Pinedo M, et al. Among authors: siwek a. J Med Chem. 2024 Sep 26;67(18):16533-16555. doi: 10.1021/acs.jmedchem.4c01367. Epub 2024 Sep 10. J Med Chem. 2024. PMID: 39256214
Zinc as a marker of affective disorders.
Siwek M, Szewczyk B, Dudek D, Styczeń K, Sowa-Kućma M, Młyniec K, Siwek A, Witkowski L, Pochwat B, Nowak G. Siwek M, et al. Among authors: siwek a. Pharmacol Rep. 2013;65(6):1512-8. doi: 10.1016/s1734-1140(13)71512-3. Pharmacol Rep. 2013. PMID: 24552999 Free article. Review.
Guanidine Derivative ADS1017, a Potent Histamine H3 Receptor Antagonist with Promising Analgesic Activity and Satisfactory Safety Profile.
Karcz T, Szczepańska K, Mogilski S, Moroz A, Olejarz-Maciej A, Humphrys LJ, Pockes S, Siwek A, Dubiel K, Staszewski M, Calmels T, Waczyński K, Kieć-Kononowicz K. Karcz T, et al. Among authors: siwek a. ACS Chem Neurosci. 2024 Dec 18;15(24):4441-4457. doi: 10.1021/acschemneuro.4c00480. Epub 2024 Dec 9. ACS Chem Neurosci. 2024. PMID: 39652796
2-(4-Fluorophenyl)-1H-benzo[d]imidazole as a Promising Template for the Development of Metabolically Robust, α1β2γ2GABA-A Receptor-Positive Allosteric Modulators.
Marcinkowska M, Fajkis-Zajączkowska N, Szafrańska K, Jończyk J, Siwek A, Mordyl B, Karcz T, Latacz G, Kolaczkowski M. Marcinkowska M, et al. Among authors: siwek a. ACS Chem Neurosci. 2023 Mar 15;14(6):1166-1180. doi: 10.1021/acschemneuro.2c00800. Epub 2023 Feb 27. ACS Chem Neurosci. 2023. PMID: 36848624 Free PMC article.
Multifunctional, Fluorene-Based Modulator of Cholinergic and GABAergic Neurotransmission as a Novel Drug Candidate for Palliative Treatment of Alzheimer's Disease.
Panek D, Pasieka A, Jończyk J, Gawlińska M, Zaręba P, Siwek A, Wolak M, Mordyl B, Głuch-Lutwin M, Latacz G, Brazzolotto X, Chantegreil F, Nachon F, Zdarova Karasova J, Pejchal J, Mzik M, Sestak V, Prchal L, Odvarkova J, Soukup O, Korabecny J, Sorf A, Hamsikova M, Zemanova L, Muckova L, Vánova N, Dryja P, Sałat K, Höfner G, Wanner K, Więckowska A, Malawska B. Panek D, et al. Among authors: siwek a. Angew Chem Int Ed Engl. 2025 Feb 3;64(6):e202420510. doi: 10.1002/anie.202420510. Epub 2024 Nov 22. Angew Chem Int Ed Engl. 2025. PMID: 39523866 Free PMC article.
Discovery of New Highly Potent Histamine H3 Receptor Antagonists, Calcium Channel Blockers, and Acetylcholinesterase Inhibitors.
Malek R, Sałat K, Totoson P, Karcz T, Refouvelet B, Skrzypczak-Wiercioch A, Maj M, Simakov A, Martin H, Siwek A, Szałaj N, Godyń J, Panek D, Więckowska A, Jozwiak K, Demougeot C, Kieć-Kononowicz K, Chabchoub F, Iriepa I, Marco-Contelles J, Ismaili L. Malek R, et al. Among authors: siwek a. ACS Chem Neurosci. 2024 Sep 18;15(18):3363-3383. doi: 10.1021/acschemneuro.4c00341. Epub 2024 Aug 29. ACS Chem Neurosci. 2024. PMID: 39208251
203 results