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Page 1
Activating PKC-ε induces HIV expression with improved tolerability.
Irrinki AM, Kaur J, Randhawa B, McFadden R, Snyder C, Truong H, Soohoo D, Hu E, Yu H, Murray BP, Lu B, Kornyeyev D, Irwan ID, Nguyen L, Yang YS, Belzile JP, Schmitz U, Appleby TC, Schultz B, Lalezari J, Deeks S, Cihlar T, Murry JP. Irrinki AM, et al. Among authors: soohoo d. PLoS Pathog. 2025 Feb 6;21(2):e1012874. doi: 10.1371/journal.ppat.1012874. eCollection 2025 Feb. PLoS Pathog. 2025. PMID: 39913544 Free PMC article.
Key Metabolic Enzymes Involved in Remdesivir Activation in Human Lung Cells.
Li R, Liclican A, Xu Y, Pitts J, Niu C, Zhang J, Kim C, Zhao X, Soohoo D, Babusis D, Yue Q, Ma B, Murray BP, Subramanian R, Xie X, Zou J, Bilello JP, Li L, Schultz BE, Sakowicz R, Smith BJ, Shi PY, Murakami E, Feng JY. Li R, et al. Among authors: soohoo d. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0060221. doi: 10.1128/AAC.00602-21. Epub 2021 Aug 17. Antimicrob Agents Chemother. 2021. PMID: 34125594 Free PMC article.
CVT-4325: a potent fatty acid oxidation inhibitor with favorable oral bioavailability.
Elzein E, Ibrahim P, Koltun DO, Rehder K, Shenk KD, Marquart TA, Jiang B, Li X, Natero R, Li Y, Nguyen M, Kerwar S, Chu N, Soohoo D, Hao J, Maydanik VY, Lustig DA, Zeng D, Leung K, Zablocki JA. Elzein E, et al. Among authors: soohoo d. Bioorg Med Chem Lett. 2004 Dec 20;14(24):6017-21. doi: 10.1016/j.bmcl.2004.09.077. Bioorg Med Chem Lett. 2004. PMID: 15546720
Discovery of Dihydrobenzoxazepinone (GS-6615) Late Sodium Current Inhibitor (Late INai), a Phase II Agent with Demonstrated Preclinical Anti-Ischemic and Antiarrhythmic Properties.
Zablocki JA, Elzein E, Li X, Koltun DO, Parkhill EQ, Kobayashi T, Martinez R, Corkey B, Jiang H, Perry T, Kalla R, Notte GT, Saunders O, Graupe M, Lu Y, Venkataramani C, Guerrero J, Perry J, Osier M, Strickley R, Liu G, Wang WQ, Hu L, Li XJ, El-Bizri N, Hirakawa R, Kahlig K, Xie C, Li CH, Dhalla AK, Rajamani S, Mollova N, Soohoo D, Lepist EI, Murray B, Rhodes G, Belardinelli L, Desai MC. Zablocki JA, et al. Among authors: soohoo d. J Med Chem. 2016 Oct 13;59(19):9005-9017. doi: 10.1021/acs.jmedchem.6b00939. Epub 2016 Oct 3. J Med Chem. 2016. PMID: 27690427
Novel inhibitors of fatty acid oxidation as potential metabolic modulators.
Elzein E, Shenk K, Ibrahim P, Marquart T, Kerwar S, Meyer S, Ahmed H, Zeng D, Chu N, Soohoo D, Wong S, Leung K, Zablocki J. Elzein E, et al. Among authors: soohoo d. Bioorg Med Chem Lett. 2004 Feb 23;14(4):973-7. doi: 10.1016/j.bmcl.2003.11.065. Bioorg Med Chem Lett. 2004. PMID: 15013004
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