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423 results

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Page 1
Showing results for spectra gs
Search for Spectre GS instead (1 results)
Mutation update: the spectra of nebulin variants and associated myopathies.
Lehtokari VL, Kiiski K, Sandaradura SA, Laporte J, Repo P, Frey JA, Donner K, Marttila M, Saunders C, Barth PG, den Dunnen JT, Beggs AH, Clarke NF, North KN, Laing NG, Romero NB, Winder TL, Pelin K, Wallgren-Pettersson C. Lehtokari VL, et al. Hum Mutat. 2014 Dec;35(12):1418-26. doi: 10.1002/humu.22693. Hum Mutat. 2014. PMID: 25205138 Free PMC article.
Furthermore, we have analyzed the NEB variants deposited in the Exome Variant Server (http://evs.gs.washington.edu/EVS/), identifying that pathogenic variants are a minor fraction of all coding variants (7%). ...
Furthermore, we have analyzed the NEB variants deposited in the Exome Variant Server (http://evs.gs.washington.edu/EVS/), identifying …
Reverse metabolomics for the discovery of chemical structures from humans.
Gentry EC, Collins SL, Panitchpakdi M, Belda-Ferre P, Stewart AK, Carrillo Terrazas M, Lu HH, Zuffa S, Yan T, Avila-Pacheco J, Plichta DR, Aron AT, Wang M, Jarmusch AK, Hao F, Syrkin-Nikolau M, Vlamakis H, Ananthakrishnan AN, Boland BS, Hemperly A, Vande Casteele N, Gonzalez FJ, Clish CB, Xavier RJ, Chu H, Baker ES, Patterson AD, Knight R, Siegel D, Dorrestein PC. Gentry EC, et al. Nature. 2024 Feb;626(7998):419-426. doi: 10.1038/s41586-023-06906-8. Epub 2023 Dec 5. Nature. 2024. PMID: 38052229 Free PMC article.
Here we present reverse metabolomics as a discovery strategy, whereby tandem mass spectrometry spectra acquired from newly synthesized compounds are searched for in public metabolomics datasets to uncover phenotypic associations. ...Because searching repositories with tand …
Here we present reverse metabolomics as a discovery strategy, whereby tandem mass spectrometry spectra acquired from newly synthesize …
Disease-modifying therapies for Parkinson disease: lessons from multiple sclerosis.
Kalia LV, Asis A, Arbour N, Bar-Or A, Bove R, Di Luca DG, Fon EA, Fox S, Gan-Or Z, Gommerman JL, Kang UJ, Klawiter EC, Koch M, Kolind S, Lang AE, Lee KK, Lincoln MR, MacDonald PA, McKeown MJ, Mestre TA, Miron VE, Ontaneda D, Rousseaux MWC, Schlossmacher MG, Schneider R, Stoessl AJ, Oh J. Kalia LV, et al. Nat Rev Neurol. 2024 Dec;20(12):724-737. doi: 10.1038/s41582-024-01023-0. Epub 2024 Oct 7. Nat Rev Neurol. 2024. PMID: 39375563 Review.
In this Roadmap article, we highlight discussions from the symposium, which focused on therapeutic targets and preclinical models, disease spectra and subclassifications, and clinical trial design and outcome measures. From these discussions, we propose areas for novel or …
In this Roadmap article, we highlight discussions from the symposium, which focused on therapeutic targets and preclinical models, disease …
Indian Guidelines on Nebulization Therapy.
Katiyar SK, Gaur SN, Solanki RN, Sarangdhar N, Suri JC, Kumar R, Khilnani GC, Chaudhary D, Singla R, Koul PA, Mahashur AA, Ghoshal AG, Behera D, Christopher DJ, Talwar D, Ganguly D, Paramesh H, Gupta KB, Kumar T M, Motiani PD, Shankar PS, Chawla R, Guleria R, Jindal SK, Luhadia SK, Arora VK, Vijayan VK, Faye A, Jindal A, Murar AK, Jaiswal A, M A, Janmeja AK, Prajapat B, Ravindran C, Bhattacharyya D, D'Souza G, Sehgal IS, Samaria JK, Sarma J, Singh L, Sen MK, Bainara MK, Gupta M, Awad NT, Mishra N, Shah NN, Jain N, Mohapatra PR, Mrigpuri P, Tiwari P, Narasimhan R, Kumar RV, Prasad R, Swarnakar R, Chawla RK, Kumar R, Chakrabarti S, Katiyar S, Mittal S, Spalgais S, Saha S, Kant S, Singh VK, Hadda V, Kumar V, Singh V, Chopra V, B V. Katiyar SK, et al. Indian J Tuberc. 2022;69 Suppl 1:S1-S191. doi: 10.1016/j.ijtb.2022.06.004. Epub 2022 Jul 11. Indian J Tuberc. 2022. PMID: 36372542
Phenomic Selection: A New and Efficient Alternative to Genomic Selection.
Robert P, Brault C, Rincent R, Segura V. Robert P, et al. Methods Mol Biol. 2022;2467:397-420. doi: 10.1007/978-1-0716-2205-6_14. Methods Mol Biol. 2022. PMID: 35451784 Review.
Recently, it has been proposed to switch molecular markers to near-infrared (NIR) spectra for inferring relationships between individuals and further performing phenomic selection (PS), analogous to genomic selection (GS). ...We further provide a review of the selec …
Recently, it has been proposed to switch molecular markers to near-infrared (NIR) spectra for inferring relationships between individ …
Raman spectra of thiolated arsenicals with biological importance.
Yang M, Sun Y, Zhang X, McCord B, McGoron AJ, Mebel A, Cai Y. Yang M, et al. Talanta. 2018 Mar 1;179:520-530. doi: 10.1016/j.talanta.2017.11.022. Epub 2017 Nov 17. Talanta. 2018. PMID: 29310270
The lack of data for Raman spectra in arsenic speciation hampers the development of new tools using SERS. Herein, we report the results of a study combining the analysis of experimental Raman spectra with that obtained from density functional calculations for some i …
The lack of data for Raman spectra in arsenic speciation hampers the development of new tools using SERS. Herein, we report the resul …
Melanocortin-4 receptor complexity in energy homeostasis,obesity and drug development strategies.
Fatima MT, Ahmed I, Fakhro KA, Akil ASA. Fatima MT, et al. Diabetes Obes Metab. 2022 Apr;24(4):583-598. doi: 10.1111/dom.14618. Epub 2022 Jan 11. Diabetes Obes Metab. 2022. PMID: 34882941 Free PMC article. Review.
Thus, the overall complexity of the MC4R signalling spectra has broadened considerably, indicating there is great potential for the development of new drugs to manage obesity and its related complications. ...
Thus, the overall complexity of the MC4R signalling spectra has broadened considerably, indicating there is great potential for the d …
Computational analysis of shotgun proteomics data.
MacCoss MJ. MacCoss MJ. Curr Opin Chem Biol. 2005 Feb;9(1):88-94. doi: 10.1016/j.cbpa.2004.12.010. Curr Opin Chem Biol. 2005. PMID: 15701459 Review.
The latest generation of tandem mass spectrometers can now acquire tens of thousands of fragmentation spectra in a matter of hours. Furthermore, quantitative proteomics methods have been developed that incorporate a stable isotope-labeled internal standard for every peptid …
The latest generation of tandem mass spectrometers can now acquire tens of thousands of fragmentation spectra in a matter of hours. F …
Gs-HSQC-NOESY versus gs-NOESY-HSQC experiments: signal attenuation due to diffusion; application to symmetrical molecules.
Gschwind RM, Xie X, Rajamohanan PR. Gschwind RM, et al. Magn Reson Chem. 2004 Mar;42(3):308-12. doi: 10.1002/mrc.1344. Magn Reson Chem. 2004. PMID: 14971015
Since the coherence-selecting gradients in these pulse sequences are separated by several delays, including the mixing time, the gs-HSQC-NOESY spectra exhibit severe signal attenuation due to diffusion effects. The respective NOE information unaffected by diffusion …
Since the coherence-selecting gradients in these pulse sequences are separated by several delays, including the mixing time, the gs-H …
General Spin Restricted Open-Shell Configuration Interaction Singles (GS-ROCIS): Implementation of Spin-Orbit Coupling and Zeeman Operators for Calculation of Optical and X-ray Absorption and Magnetic Circular Dichroism Spectra of Magnetically Coupled Transition Metal Systems.
Leyser da Costa Gouveia T, Lang L, Maganas D, Neese F. Leyser da Costa Gouveia T, et al. J Phys Chem A. 2025 Oct 9;129(40):9486-9503. doi: 10.1021/acs.jpca.5c05086. Epub 2025 Sep 30. J Phys Chem A. 2025. PMID: 41025147 Free PMC article.
The implementation of the mentioned operators allows for the calculation of magnetic circularly polarized dichroism (MCD), L-edge X-ray absorption spectra (XAS) and X-ray magnetic circularly polarized dichroism (XMCD) spectra. The method was tested on calculating th …
The implementation of the mentioned operators allows for the calculation of magnetic circularly polarized dichroism (MCD), L-edge X-ray abso …
423 results