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Year Number of Results
1951 1
1952 1
1953 3
1954 3
1955 1
1968 1
2011 1
2012 2
2013 1
2015 1
2017 3
2018 4
2019 2
2020 7
2021 6
2022 2
2023 6
2024 7
2025 7

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55 results

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Page 1
Plasma membrane preassociation drives β-arrestin coupling to receptors and activation.
Grimes J, Koszegi Z, Lanoiselée Y, Miljus T, O'Brien SL, Stepniewski TM, Medel-Lacruz B, Baidya M, Makarova M, Mistry R, Goulding J, Drube J, Hoffmann C, Owen DM, Shukla AK, Selent J, Hill SJ, Calebiro D. Grimes J, et al. Among authors: stepniewski tm. Cell. 2023 May 11;186(10):2238-2255.e20. doi: 10.1016/j.cell.2023.04.018. Epub 2023 May 4. Cell. 2023. PMID: 37146613 Free PMC article.
Molecular insights into atypical modes of β-arrestin interaction with seven transmembrane receptors.
Maharana J, Sano FK, Sarma P, Yadav MK, Duan L, Stepniewski TM, Chaturvedi M, Ranjan A, Singh V, Saha S, Mahajan G, Chami M, Shihoya W, Selent J, Chung KY, Banerjee R, Nureki O, Shukla AK. Maharana J, et al. Among authors: stepniewski tm. Science. 2024 Jan 5;383(6678):101-108. doi: 10.1126/science.adj3347. Epub 2024 Jan 4. Science. 2024. PMID: 38175886 Free PMC article.
Location-biased β-arrestin conformations direct GPCR signaling.
Pham U, Chundi A, Stępniewski TM, Darbha S, Eiger DS, Gazula S, Gardner J, Hicks C, Selent J, Rajagopal S. Pham U, et al. Among authors: stepniewski tm. bioRxiv [Preprint]. 2024 Sep 26:2024.09.24.614742. doi: 10.1101/2024.09.24.614742. bioRxiv. 2024. PMID: 39386521 Free PMC article. Preprint.
G protein-specific mechanisms in the serotonin 5-HT2A receptor regulate psychosis-related effects and memory deficits.
Kossatz E, Diez-Alarcia R, Gaitonde SA, Ramon-Duaso C, Stepniewski TM, Aranda-Garcia D, Muneta-Arrate I, Tepaz E, Saen-Oon S, Soliva R, Shahraki A, Moreira D, Brea J, Loza MI, de la Torre R, Kolb P, Bouvier M, Meana JJ, Robledo P, Selent J. Kossatz E, et al. Among authors: stepniewski tm. Nat Commun. 2024 May 29;15(1):4307. doi: 10.1038/s41467-024-48196-2. Nat Commun. 2024. PMID: 38811567 Free PMC article.
Large scale investigation of GPCR molecular dynamics data uncovers allosteric sites and lateral gateways.
Aranda-García D, Stepniewski TM, Torrens-Fontanals M, García-Recio A, Lopez-Balastegui M, Medel-Lacruz B, Morales-Pastor A, Peralta-García A, Dieguez-Eceolaza M, Sotillo-Nuñez D, Ding T, Drabek M, Jacquemard C, Jakowiecki J, Jespers W, Jiménez-Rosés M, Jun-Yu-Lim V, Nicoli A, Orzel U, Shahraki A, Tiemann JKS, Ledesma-Martin V, Nerín-Fonz F, Suárez-Dou S, Canal O, Pándy-Szekeres G, Mao J, Gloriam DE, Kellenberger E, Latek D, Guixà-González R, Gutiérrez-de-Terán H, Tikhonova IG, Hildebrand PW, Filizola M, Babu MM, Di Pizio A, Filipek S, Kolb P, Cordomi A, Giorgino T, Marti-Solano M, Selent J. Aranda-García D, et al. Among authors: stepniewski tm. Nat Commun. 2025 Feb 27;16(1):2020. doi: 10.1038/s41467-025-57034-y. Nat Commun. 2025. PMID: 40016203 Free PMC article.
A Structural Mechanism for Noncanonical GPCR Signal Transduction in the Hedgehog Pathway.
Steiner WP, Iverson N, Liu G, Venkatakrishnan V, Wu J, Stepniewski TM, Michaelson Z, Bröckel JW, Zhu JF, Bruystens J, Lee A, Nelson I, Bertinetti D, Arveseth CD, Tan G, Spaltenstein P, Xu J, Hüttenhain R, Kay M, Herberg FW, Cao E, Selent J, Anand GS, Dunbrack RL Jr, Taylor SS, Myers BR. Steiner WP, et al. Among authors: stepniewski tm. bioRxiv [Preprint]. 2025 May 27:2024.10.31.621410. doi: 10.1101/2024.10.31.621410. bioRxiv. 2025. PMID: 39554190 Free PMC article. Preprint.
Biodiversity2Drugs-Renaissance of exploring nature-derived peptides for GPCR ligand discovery.
Gruber CW, Beets I, Boudreault PL, Bolzani VDS, Carlsson J, Fernandes PA, Freissmuth M, Gilles N, Göransson U, Hauser AS, Heinis C, Kool J, Lubell WD, Modica MV, Selent J, Tytgat J, Undheim EAB; Biodiversity2Drugs Consortium. Gruber CW, et al. Br J Pharmacol. 2025 Aug;182(16):3691-3694. doi: 10.1111/bph.70072. Epub 2025 May 29. Br J Pharmacol. 2025. PMID: 40442894 No abstract available.
Multiple intramolecular triggers converge to preferential G protein coupling in the CB2R.
Morales-Pastor A, Miljuš T, Dieguez-Eceolaza M, Stępniewski TM, Ledesma-Martin V, Heydenreich FM, Flock T, Plouffe B, Le Gouill C, Duchaine J, Sykes DA, Nicholson C, Koers EJ, Guba W, Rufer AC, Grether U, Bouvier M, Veprintsev DB, Selent J. Morales-Pastor A, et al. Among authors: stepniewski tm. Nat Commun. 2025 Jun 11;16(1):5265. doi: 10.1038/s41467-025-60003-0. Nat Commun. 2025. PMID: 40500255 Free PMC article.
Phosphorylation barcodes direct biased chemokine signaling at CXCR3.
Eiger DS, Smith JS, Shi T, Stepniewski TM, Tsai CF, Honeycutt C, Boldizsar N, Gardner J, Nicora CD, Moghieb AM, Kawakami K, Choi I, Hicks C, Zheng K, Warman A, Alagesan P, Knape NM, Huang O, Silverman JD, Smith RD, Inoue A, Selent J, Jacobs JM, Rajagopal S. Eiger DS, et al. Among authors: stepniewski tm. Cell Chem Biol. 2023 Apr 20;30(4):362-382.e8. doi: 10.1016/j.chembiol.2023.03.006. Epub 2023 Apr 7. Cell Chem Biol. 2023. PMID: 37030291 Free PMC article.
55 results