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The following term was not found in PubMed: tragier
Page 1
Showing results for tragier ob
Search for Stragier OB instead (3 results)
Lipocalin-2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high-fat diet-fed Ob/Ob mice.
Kim KE, Lee J, Shin HJ, Jeong EA, Jang HM, Ahn YJ, An HS, Lee JY, Shin MC, Kim SK, Yoo WG, Kim WH, Roh GS. Kim KE, et al. Hepatology. 2023 Mar 1;77(3):888-901. doi: 10.1002/hep.32569. Epub 2023 Feb 17. Hepatology. 2023. PMID: 35560370 Free PMC article.
In addition, HFD-fed ob/ob mice were treated with gadolinium trichloride to deplete Kupffer cells. The LX-2 human HSCs and primary HSCs from ob/ob mice were used to investigate the effects of LCN2 on HSC activation. ...HFD-fed DKO mice showed a marked …
In addition, HFD-fed ob/ob mice were treated with gadolinium trichloride to deplete Kupffer cells. The LX-2 human HSCs and pri …
Novel insights into the genetically obese (ob/ob) and diabetic (db/db) mice: two sides of the same coin.
Suriano F, Vieira-Silva S, Falony G, Roumain M, Paquot A, Pelicaen R, Régnier M, Delzenne NM, Raes J, Muccioli GG, Van Hul M, Cani PD. Suriano F, et al. Microbiome. 2021 Jun 28;9(1):147. doi: 10.1186/s40168-021-01097-8. Microbiome. 2021. PMID: 34183063 Free PMC article.
However, although ob/ob and db/db mice are similarly gaining weight and developing massive obesity, db/db mice are more diabetic than ob/ob mice. ...In addition, liver steatosis was more pronounced in the ob/ob mice than in db/db mice. We …
However, although ob/ob and db/db mice are similarly gaining weight and developing massive obesity, db/db mice are more diabet …
Leptin receptors.
Gorska E, Popko K, Stelmaszczyk-Emmel A, Ciepiela O, Kucharska A, Wasik M. Gorska E, et al. Eur J Med Res. 2010 Nov 4;15 Suppl 2(Suppl 2):50-4. doi: 10.1186/2047-783x-15-s2-50. Eur J Med Res. 2010. PMID: 21147620 Free PMC article. Review.
Leptin or obesity receptor (Ob-R) is a member of class I cytokine receptor family. Ob-R, expressed in six isoforms, is the product of alternative RNA splicing of db gene. ...Short leptin isoforms (Ob-Ra, Ob-Rc, Ob-Rd, and Ob-Re) that cont …
Leptin or obesity receptor (Ob-R) is a member of class I cytokine receptor family. Ob-R, expressed in six isoforms, is the pro …
Leptin-deficient ob/ob mice exhibit periodontitis phenotype and altered oral microbiome.
Li Z, Zheng Z, Pathak JL, Li H, Wu G, Xu S, Wang T, Cheng H, Piao Z, Jaspers RT, Wu L. Li Z, et al. J Periodontal Res. 2023 Apr;58(2):392-402. doi: 10.1111/jre.13099. Epub 2023 Jan 29. J Periodontal Res. 2023. PMID: 36710264
Higher numbers of osteoclasts were observed in ob/ob mice alveolar bone adjacent to the molar root. Epithelial hyperplasia in gingiva and disordered periodontal ligaments was observed in ob/ob mice. RANKL/OPG expression ratio was increased in ob …
Higher numbers of osteoclasts were observed in ob/ob mice alveolar bone adjacent to the molar root. Epithelial hyperplasia in …
The OB protein (leptin) pathway--a link between adipose tissue mass and central neural networks.
Campfield LA, Smith FJ, Burn P. Campfield LA, et al. Horm Metab Res. 1996 Dec;28(12):619-32. doi: 10.1055/s-2007-979867. Horm Metab Res. 1996. PMID: 9013731 Review.
The field has rapidly moved from cloning of the ob gene to demonstration of complex regulation of ob gene expression in adipose tissue in rats and humans, and then the demonstration of potent biological activity of OB protein in ob/ob, diet-indu …
The field has rapidly moved from cloning of the ob gene to demonstration of complex regulation of ob gene expression in adipos …
OB-RGRP regulates the phosphorylation of JAK2 and STAT3 in primary rat adipocytes.
Li X, Shi W, Wu G, Qin X, Wan G, Zeng Q, Hu Y. Li X, et al. Artif Cells Nanomed Biotechnol. 2019 Dec;47(1):3664-3670. doi: 10.1080/21691401.2019.1632322. Artif Cells Nanomed Biotechnol. 2019. PMID: 31841394 Free article.
OB-RGRP expression vector and OB-RGRP siRNA (si-OB-RGRP) were constructed and transfected into adipocytes. Adipocytes were then divided into five groups: (1) Control; (2) Vector (empty expression vector); (3) OB-RGRP (OB-RGRP expression vector); …
OB-RGRP expression vector and OB-RGRP siRNA (si-OB-RGRP) were constructed and transfected into adipocytes. Adipocytes w …
Carbon tetrachloride does not promote hepatic fibrosis in ob/ob mice via downregulation of lipocalin-2 protein.
Shin HJ, Kim KE, An HS, Jeong EA, Oh J, Sun Y, Park DJ, Lee J, Yang J, Roh GS. Shin HJ, et al. Redox Biol. 2025 Mar;80:103506. doi: 10.1016/j.redox.2025.103506. Epub 2025 Jan 16. Redox Biol. 2025. PMID: 39832399 Free PMC article.
CCl(4) treatment attenuated liver weight and lipogenesis in ob/ob mice. Increased hepatic fibrosis-related proteins were reduced in CCl(4)-treated ob/ob mice compared with CCl(4)-treated WT mice. ...Hepatic heme oxygenase-1 protein was reduced in CCl(4 …
CCl(4) treatment attenuated liver weight and lipogenesis in ob/ob mice. Increased hepatic fibrosis-related proteins were reduc …
Ob/ob serum promotes a mesenchymal cell phenotype in B16BL6 melanoma cells.
Kushiro K, Núñez NP. Kushiro K, et al. Clin Exp Metastasis. 2011 Dec;28(8):877-86. doi: 10.1007/s10585-011-9418-4. Epub 2011 Aug 31. Clin Exp Metastasis. 2011. PMID: 21879359
Others have shown that B16BL6 melanoma cells metastasize more aggressively in obese ob/ob than in lean mice. However, the mechanism by which obesity promotes B16BL6 melanoma metastasis in ob/ob mice has not been identified. ...We showed that ob/ …
Others have shown that B16BL6 melanoma cells metastasize more aggressively in obese ob/ob than in lean mice. However, the mech …
Trigeminal Pain Responses in Obese ob/ob Mice Are Modality-Specific.
Rossi HL, Raj NR, Marquez de Prado B, Kuburas A, Luu AKS, Barr GA, Recober A. Rossi HL, et al. Neuroscience. 2019 Sep 1;415:121-134. doi: 10.1016/j.neuroscience.2019.06.043. Epub 2019 Jul 8. Neuroscience. 2019. PMID: 31295530
To test this, we first evaluated trigeminal thermal nociception in leptin deficient (ob/ob) and control mice using an operant thermal assay. Unexpectedly, we found significant hypoalgesia in ob/ob mice. Because thermal hypoalgesia also occurs in mice l …
To test this, we first evaluated trigeminal thermal nociception in leptin deficient (ob/ob) and control mice using an operant …
Anti-obesity effect of sulforaphane in broccoli leaf extract on 3T3-L1 adipocytes and ob/ob mice.
Ranaweera SS, Natraj P, Rajan P, Dayarathne LA, Mihindukulasooriya SP, Dinh DTT, Jee Y, Han CH. Ranaweera SS, et al. J Nutr Biochem. 2022 Feb;100:108885. doi: 10.1016/j.jnutbio.2021.108885. Epub 2021 Oct 13. J Nutr Biochem. 2022. PMID: 34655754
Western blot analysis confirmed that SFN and BLE increased the phosphorylation levels of both AMPK (Thr172) and ACC (Ser79), and reduced the expression of HMGCR in liver and white adipose tissues of ob/ob mice. Histological analysis revealed that SFN and BLE amelior …
Western blot analysis confirmed that SFN and BLE increased the phosphorylation levels of both AMPK (Thr172) and ACC (Ser79), and reduced the …
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