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Year Number of Results
1986 1
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2005 1
2006 6
2007 5
2008 3
2009 3
2010 3
2011 5
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80 results

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Page 1
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer.
Sharma S, Chung CY, Uryu S, Petrovic J, Cao J, Rickard A, Nady N, Greasley S, Johnson E, Brodsky O, Khan S, Wang H, Wang Z, Zhang Y, Tsaparikos K, Chen L, Mazurek A, Lapek J, Kung PP, Sutton S, Richardson PF, Greenwald EC, Yamazaki S, Jones R, Maegley KA, Bingham P, Lam H, Stupple AE, Kamal A, Chueh A, Cuzzupe A, Morrow BJ, Ren B, Carrasco-Pozo C, Tan CW, Bhuva DD, Allan E, Surgenor E, Vaillant F, Pehlivanoglu H, Falk H, Whittle JR, Newman J, Cursons J, Doherty JP, White KL, MacPherson L, Devlin M, Dennis ML, Hattarki MK, De Silva M, Camerino MA, Butler MS, Dolezal O, Pilling P, Foitzik R, Stupple PA, Lagiakos HR, Walker SR, Hediyeh-Zadeh S, Nuttall S, Spall SK, Charman SA, Connor T, Peat TS, Avery VM, Bozikis YE, Yang Y, Zhang M, Monahan BJ, Voss AK, Thomas T, Street IP, Dawson SJ, Dawson MA, Lindeman GJ, Davis MJ, Visvader JE, Paul TA. Sharma S, et al. Among authors: street ip. Cell Chem Biol. 2023 Oct 19;30(10):1191-1210.e20. doi: 10.1016/j.chembiol.2023.07.005. Epub 2023 Aug 8. Cell Chem Biol. 2023. PMID: 37557181 Free article.
Inhibitors of histone acetyltransferases KAT6A/B induce senescence and arrest tumour growth.
Baell JB, Leaver DJ, Hermans SJ, Kelly GL, Brennan MS, Downer NL, Nguyen N, Wichmann J, McRae HM, Yang Y, Cleary B, Lagiakos HR, Mieruszynski S, Pacini G, Vanyai HK, Bergamasco MI, May RE, Davey BK, Morgan KJ, Sealey AJ, Wang B, Zamudio N, Wilcox S, Garnham AL, Sheikh BN, Aubrey BJ, Doggett K, Chung MC, de Silva M, Bentley J, Pilling P, Hattarki M, Dolezal O, Dennis ML, Falk H, Ren B, Charman SA, White KL, Rautela J, Newbold A, Hawkins ED, Johnstone RW, Huntington ND, Peat TS, Heath JK, Strasser A, Parker MW, Smyth GK, Street IP, Monahan BJ, Voss AK, Thomas T. Baell JB, et al. Among authors: street ip. Nature. 2018 Aug;560(7717):253-257. doi: 10.1038/s41586-018-0387-5. Epub 2018 Aug 1. Nature. 2018. PMID: 30069049
Facilitating conservation.
Chakrabarty P, Negi S, Andrés RM, Favaro B, Singh B, Hilleary R, Arthur PK, Street IH, Cheung MK, Parsons M, Easun T, Cingl L, Wang L, Widge AS, Li R, Zhou K, Pinto PT, Yoho R, Buschke F. Chakrabarty P, et al. Among authors: street ih. Science. 2017 Apr 21;356(6335):242-244. doi: 10.1126/science.aan4270. Epub 2017 Apr 20. Science. 2017. PMID: 28428380 No abstract available.
Hoarseness in children.
Sood S, Street I, Donne A. Sood S, et al. Among authors: street i. Br J Hosp Med (Lond). 2017 Dec 2;78(12):678-683. doi: 10.12968/hmed.2017.78.12.678. Br J Hosp Med (Lond). 2017. PMID: 29240505 Review.
Catalytic inhibition of KAT6/KAT7 enhances the efficacy and overcomes primary and acquired resistance to Menin inhibitors in MLL leukaemia.
Gordon SJV, Perner F, MacPherson L, Wenge DV, Bourgeois W, Fennell K, Klaus T, Petrovic J, Horvath J, Cao J, Lapek J, Uryu S, White J, Lam EYN, Mu XJ, Chan YC, Gillespie A, Blyth B, Camerino MA, Bozikis YE, Holze H, Knezevic K, Balic J, Stupple PA, Street IP, Monahan BJ, Sharma S, Wainwright EN, Vassiliadis D, Paul TA, Armstrong SA, Dawson MA. Gordon SJV, et al. Among authors: street ip. bioRxiv [Preprint]. 2024 Dec 12:2024.12.11.627663. doi: 10.1101/2024.12.11.627663. bioRxiv. 2024. Update in: Cancer Discov. 2025 Oct 6;15(10):2117-2138. doi: 10.1158/2159-8290.CD-24-1517. PMID: 39713447 Free PMC article. Updated. Preprint.
HBO1 is required for the maintenance of leukaemia stem cells.
MacPherson L, Anokye J, Yeung MM, Lam EYN, Chan YC, Weng CF, Yeh P, Knezevic K, Butler MS, Hoegl A, Chan KL, Burr ML, Gearing LJ, Willson T, Liu J, Choi J, Yang Y, Bilardi RA, Falk H, Nguyen N, Stupple PA, Peat TS, Zhang M, de Silva M, Carrasco-Pozo C, Avery VM, Khoo PS, Dolezal O, Dennis ML, Nuttall S, Surjadi R, Newman J, Ren B, Leaver DJ, Sun Y, Baell JB, Dovey O, Vassiliou GS, Grebien F, Dawson SJ, Street IP, Monahan BJ, Burns CJ, Choudhary C, Blewitt ME, Voss AK, Thomas T, Dawson MA. MacPherson L, et al. Among authors: street ip. Nature. 2020 Jan;577(7789):266-270. doi: 10.1038/s41586-019-1835-6. Epub 2019 Dec 11. Nature. 2020. PMID: 31827282
Catalytic Inhibition of KAT6/KAT7 Enhances the Efficacy and Overcomes Primary and Acquired Resistance to Menin Inhibitors in MLL Leukemia.
Gordon SJV, Perner F, MacPherson L, Fennell KA, Wenge DV, Bourgeois W, Klaus T, Plenge T, Murat A, Petrovic J, Horvath J, Cao JQ, Lapek JD Jr, Uryu S, White JR, Lam EYN, Mu XJ, Chan YC, Gillespie A, Blyth BJ, Camerino MA, Bozikis YE, Holze H, Knezevic K, Balic J, Stupple PA, Street IP, Monahan BJ, Sharma S, Wainwright EN, Vassiliadis D, Paul TA, Armstrong SA, Dawson MA. Gordon SJV, et al. Among authors: street ip. Cancer Discov. 2025 Oct 6;15(10):2117-2138. doi: 10.1158/2159-8290.CD-24-1517. Cancer Discov. 2025. PMID: 40536420
Cytokinin and the cell cycle.
Schaller GE, Street IH, Kieber JJ. Schaller GE, et al. Among authors: street ih. Curr Opin Plant Biol. 2014 Oct;21:7-15. doi: 10.1016/j.pbi.2014.05.015. Epub 2014 Jul 1. Curr Opin Plant Biol. 2014. PMID: 24994531 Review.
Sunshine outside the ivory tower.
Welch A, Helena C, Street I. Welch A, et al. Among authors: street i. Science. 2017 Sep 22;357(6357):1322. doi: 10.1126/science.357.6357.1322. Science. 2017. PMID: 28935807 No abstract available.
80 results