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A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner.
Sylvain A, Stoehr N, Ma F, Cernijenko A, Schröder M, Khoshouei M, Vogelsanger M, Schoenboerner M, Burke A, Rao P, Solomon JM, Paulk J, Xu L, Dawson J, Begue D, Lefeuvre P, Ahrne E, Hofmann A, Dickson CJ, Arabin P, Zimmerlin A, Kiffe M, Froehlicher M, Boersig T, Elhajouji A, Brichet M, Menon S, Liu S, Mueller M, Wartchow CA, Lin J, Gloria YC, Dickhöfer S, Weber ANR, Welzel T, Kuemmerle-Deschner J, Farady CJ, Pulz R, Bornancin F, Buckley DL, Bassi ZI. Sylvain A, et al. Cell Chem Biol. 2025 Jul 17;32(7):955-968.e13. doi: 10.1016/j.chembiol.2025.06.005. Epub 2025 Jul 9. Cell Chem Biol. 2025. PMID: 40639372
Differential role for CD277 as a co-regulator of the immune signal in T and NK cells.
Messal N, Mamessier E, Sylvain A, Celis-Gutierrez J, Thibult ML, Chetaille B, Firaguay G, Pastor S, Guillaume Y, Wang Q, Hirsch I, Nunès JA, Olive D. Messal N, et al. Among authors: sylvain a. Eur J Immunol. 2011 Dec;41(12):3443-54. doi: 10.1002/eji.201141404. Epub 2011 Nov 3. Eur J Immunol. 2011. PMID: 21918970 Free article.
The neuron-specific chromatin regulatory subunit BAF53b is necessary for synaptic plasticity and memory.
Vogel-Ciernia A, Matheos DP, Barrett RM, Kramár EA, Azzawi S, Chen Y, Magnan CN, Zeller M, Sylvain A, Haettig J, Jia Y, Tran A, Dang R, Post RJ, Chabrier M, Babayan AH, Wu JI, Crabtree GR, Baldi P, Baram TZ, Lynch G, Wood MA. Vogel-Ciernia A, et al. Among authors: sylvain a. Nat Neurosci. 2013 May;16(5):552-61. doi: 10.1038/nn.3359. Epub 2013 Mar 24. Nat Neurosci. 2013. PMID: 23525042 Free PMC article.
15 results