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Unguided de-escalation from ticagrelor to clopidogrel in stabilised patients with acute myocardial infarction undergoing percutaneous coronary intervention (TALOS-AMI): an investigator-initiated, open-label, multicentre, non-inferiority, randomised trial.
Kim CJ, Park MW, Kim MC, Choo EH, Hwang BH, Lee KY, Choi YS, Kim HY, Yoo KD, Jeon DS, Shin ES, Jeong YH, Seung KB, Jeong MH, Yim HW, Ahn Y, Chang K; TALOS-AMI investigators. Kim CJ, et al. Lancet. 2021 Oct 9;398(10308):1305-1316. doi: 10.1016/S0140-6736(21)01445-8. Lancet. 2021. PMID: 34627490 Clinical Trial.
Dual Antiplatelet Therapy De-Escalation in Stabilized Myocardial Infarction With High Ischemic Risk: Post Hoc Analysis of the TALOS-AMI Randomized Clinical Trial.
Lee M, Byun S, Lim S, Choo EH, Lee KY, Moon D, Choi IJ, Hwang BH, Kim CJ, Park MW, Choi YS, Kim HY, Yoo KD, Jeon DS, Yim HW, Chang K; TALOS-AMI Investigators. Lee M, et al. JAMA Cardiol. 2024 Feb 1;9(2):125-133. doi: 10.1001/jamacardio.2023.4587. JAMA Cardiol. 2024. PMID: 38117483 Free PMC article. Clinical Trial.
Deescalation From Ticagrelor to Clopidogrel for Myocardial Infarction With Chronic Kidney Disease: A Secondary Analysis of a Randomized Clinical Trial.
Kim SH, Lee KY, Byeon J, Sa YK, Hwang BH, Kim CJ, Choo EH, Lim S, Choi IJ, Choi YS, Park CS, Park MW, Her SH, Lee M, Chang K; TALOS-AMI Investigators. Kim SH, et al. JAMA Netw Open. 2025 May 1;8(5):e2511297. doi: 10.1001/jamanetworkopen.2025.11297. JAMA Netw Open. 2025. PMID: 40392554 Free PMC article. Clinical Trial.
Prognosis and the Effect of De-Escalation of Antiplatelet Therapy After Nuisance Bleeding in Patients With Myocardial Infarction.
Choo EH, Choi IJ, Lim S, Moon D, Kim CJ, Park MW, Kim MC, Hwang BH, Lee KY, Seok Choi Y, Kim HY, Yoo KD, Jeon DS, Ahn Y, Chang K; TALOS-AMI Investigators. Choo EH, et al. Circ Cardiovasc Interv. 2022 Dec;15(12):e012157. doi: 10.1161/CIRCINTERVENTIONS.122.012157. Epub 2022 Nov 16. Circ Cardiovasc Interv. 2022. PMID: 36382599 Clinical Trial.