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The Tools for Integrated Management of Childhood Illness (TIMCI) study protocol: a multi-country mixed-method evaluation of pulse oximetry and clinical decision support algorithms.
Beynon F, Langet H, Bohle LF, Awasthi S, Ndiaye O, Machoki M'Imunya J, Masanja H, Horton S, Ba M, Cicconi S, Emmanuel-Fabula M, Faye PM, Glass TR, Keitel K, Kumar D, Kumar G, Levine GA, Matata L, Mhalu G, Miheso A, Mjungu D, Njiri F, Reus E, Ruffo M, Schär F, Sharma K, Storey HL, Masanja I, Wyss K, D'Acremont V; TIMCI Collaborator Group. Beynon F, et al. Glob Health Action. 2024 Dec 31;17(1):2326253. doi: 10.1080/16549716.2024.2326253. Epub 2024 Apr 29. Glob Health Action. 2024. PMID: 38683158 Free PMC article. Clinical Trial.
Effectiveness of introducing pulse oximetry and clinical decision support algorithms for the management of sick children in primary care in Kenya and Senegal on referral and antibiotic prescription: the TIMCI quasi-experimental pre-post study.
Langet H, Faye PM, Njiri F, Cicconi S, Levine GA, Glass TR, Kosgei RJ, Ngari K, Schaer F, Thiongane A, Tine JAD, Ba M, Bohle LF, Emmanuel-Fabula M, Faye MM, Horton S, Miheso A, Mugo M, Ngutu M, Ruffo M, Shauri J, Sougou NM, D'Acremont V, Wyss K, Ndiaye O, Beynon F; TIMCI Collaborator Group. Langet H, et al. EClinicalMedicine. 2025 May 12;83:103196. doi: 10.1016/j.eclinm.2025.103196. eCollection 2025 May. EClinicalMedicine. 2025. PMID: 40474998 Free PMC article.
Effectiveness of introducing pulse oximetry and clinical decision support algorithms for the management of sick children in primary care in India and Tanzania on hospitalisation and mortality: the TIMCI pragmatic cluster randomised controlled trial.
Beynon F, Mhalu G, Kumar D, Cicconi S, Langet H, Levine GA, Agarwal G, Festo C, Glass TR, Jacob A, Kumar G, Lwambura S, Matata L, Mkopi A, Moshiro R, Schaer F, Bandi V, Bohle LF, Emmanuel-Fabula M, Horlacher M, Horton S, Maiba J, Makawia S, Masanja N, Mjungu D, Mtebene IE, Odek O, Oliveira V, Pantjushenko E, Reus E, Ruffo M, Sharma K, Storey H, Tyagi M, D'Acremont V, Masanja H, Awasthi S, Wyss K; TIMCI Collaborator Group. Beynon F, et al. EClinicalMedicine. 2025 Jul 3;85:103306. doi: 10.1016/j.eclinm.2025.103306. eCollection 2025 Jul. EClinicalMedicine. 2025. PMID: 40686675 Free PMC article.
Costs of testing sick children in primary care with pulse oximetry: Evidence from four countries, both with and without electronic clinical decision support.
Horton S, Adombi U, Beynon F, Emmanuel-Fabula M, Herrick T, Kumar S, Makawia S, Mugo M, Onah M, Ruffo M, Awasthi S, Ba M, Bohle LF, Cicconi S, Langet H, Faye PM, Masanja H, Miheso A, Mjungu D, Machoki M'Imunya J, Ndiaye O, Sharma K, D'Acremont V, Wyss K; TIMCI Collaborator Group. Horton S, et al. PLOS Glob Public Health. 2025 Jul 1;5(7):e0004644. doi: 10.1371/journal.pgph.0004644. eCollection 2025. PLOS Glob Public Health. 2025. PMID: 40591534 Free PMC article.