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Melatonin for prevention of delirium in patients receiving mechanical ventilation in the intensive care unit: a multiarm multistage adaptive randomized controlled clinical trial (DEMEL).
Mekontso Dessap A, Ricard JD, Contou D, Desnos C, Decavèle M, Sonneville R, Vivier E, Terzi N, Callahan JC, Jochmans S, Leon R, Carreira S, Nseir S, Chemouni F, Castelain V, Paul M, Benoist JF, Audureau E, Razazi K; CARMAS and the REVA research networks, on behalf of the DEMEL Investigators. Mekontso Dessap A, et al. Intensive Care Med. 2025 Jul;51(7):1292-1305. doi: 10.1007/s00134-025-08002-z. Epub 2025 Jul 3. Intensive Care Med. 2025. PMID: 40608082 Free PMC article. Clinical Trial.
Efficacy and tolerance of early administration of tranexamic acid in patients with cirrhosis presenting with acute upper gastrointestinal bleeding: a study protocol for a multicentre, randomised, double-blind, placebo-controlled trial (the EXARHOSE study).
Heidet M, Amathieu R, Audureau E, Augusto O, Nicolazo de Barmon V, Rialland A, Schmitz D, Pierrang F, Marty J, Chollet-Xémard C, Thirion O, Jacob L. Heidet M, et al. Among authors: thirion o. BMJ Open. 2018 Aug 10;8(8):e021943. doi: 10.1136/bmjopen-2018-021943. BMJ Open. 2018. PMID: 30099397 Free PMC article.