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1963 1
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54 results

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Page 1
Effects of Oral ALZ-801/Valiltramiprosate on Plasma Biomarkers, Brain Hippocampal Volume, and Cognition: Results of 2-Year Single-Arm, Open-Label, Phase 2 Trial in APOE4 Carriers with Early Alzheimer's Disease.
Hey JA, Abushakra S, Blennow K, Reiman EM, Hort J, Prins ND, Sheardova K, Kesslak P, Shen L, Zhu X, Albayrak A, Paul J, Schaefer JF, Power A, Tolar M. Hey JA, et al. Among authors: tolar m. Drugs. 2024 Jul;84(7):811-823. doi: 10.1007/s40265-024-02067-8. Epub 2024 Jun 20. Drugs. 2024. PMID: 38902571 Free PMC article. Clinical Trial.
Analysis of Cerebrospinal Fluid, Plasma β-Amyloid Biomarkers, and Cognition from a 2-Year Phase 2 Trial Evaluating Oral ALZ-801/Valiltramiprosate in APOE4 Carriers with Early Alzheimer's Disease Using Quantitative Systems Pharmacology Model.
Hey JA, Yu JY, Abushakra S, Schaefer JF, Power A, Kesslak P, Tolar M. Hey JA, et al. Among authors: tolar m. Drugs. 2024 Jul;84(7):825-839. doi: 10.1007/s40265-024-02068-7. Epub 2024 Jun 20. Drugs. 2024. PMID: 38902572 Free PMC article. Clinical Trial.
A living band-aid for epidermolysis bullosa.
Tolar J, Tolar M. Tolar J, et al. Among authors: tolar m. Blood Transfus. 2015 Jan;13(1):1-2. doi: 10.2450/2014.0289-14. Blood Transfus. 2015. PMID: 25636127 Free PMC article. No abstract available.
Biotech leaders call for free press.
Cohen R, Holtzman S, Levin JM, Maraganore JM; Signatories to the Statement. Cohen R, et al. Nat Biotechnol. 2018 Oct 11;36(10):920-922. doi: 10.1038/nbt.4271. Nat Biotechnol. 2018. PMID: 30307914 No abstract available.
US immigration order strikes against biotech.
Levin JM, Holtzman SH, Maraganore J, Hastings PJ, Cohen R, Dahiyat B, Adams J, Adams C, Ahrens B, Albers J, Aspinall MG, Audia JE, Babler M, Barrett P, Barry Z, Bermingham N, Bloch S, Blum RI, Bolno PB, Bonney MW, Booth B, Bradbury DM, Brauer SK, Byers B, Cagnoni PJ, Cali BM, Ciechanover I, Clark C, Clayman MD, Cleland JL, Cobb P, Cooper R, Currie MG, Diekman J, Dobmeier EL, Doerfler D, Donley EL, Dunsire D, During M, Eckstein JW, Elenko E, Exter NA, Fleming JJ, Flesher GJ, Formela JF, Forrester R, Francois C, Franklin H, Freeman MW, Furst H, Gage LP, Galakatos N, Gallagher BM, Geraghty JA, Gill S, Goeddel DV, Goldsmith MA, Gowen M, Goyal V, Graney T, Grayzel D, Greene B, Grint P, Gutierrez-Ramos JC, Haney B, Ha-Ngoc T, Harris T, Hasnain F, Hata YS, Hecht P, Henshaw L, Heyman R, Hoppenot H, Horvitz HR, Hughes TE, Hutton WS, Isaacs ST, Jenkins A, Jonker J, Kaplan J, Karsen P, Keiper J, Kim J, Kindler J, King R, King V, Kjellson N, Koenig S, Koenig G, Kolchinsky P, Laikind P, Langer RB, Lee JJ, Leff JS, Leicher BA, Leschly N, Levin A, Levin M, Levine AJ, Levy A, Liu DR, Lodish HF, Lopatin U, Love TW, Macdonald G, Maderis GJ, Mahadevia A, Mahanthappa NK, Martin JF, Martin A, Martucci… See abstract for full author list ➔ Levin JM, et al. Among authors: tolar m. Nat Biotechnol. 2017 Mar 7;35(3):204-206. doi: 10.1038/nbt.3824. Nat Biotechnol. 2017. PMID: 28267733 No abstract available.
APOLLOE4 Phase 3 study of oral ALZ-801/valiltramiprosate in APOE ε4/ε4 homozygotes with early Alzheimer's disease: Trial design and baseline characteristics.
Abushakra S, Porsteinsson AP, Sabbagh M, Watson D, Power A, Liang E, MacSweeney E, Boada M, Flint S, McLaine R, Kesslak JP, Hey JA, Tolar M. Abushakra S, et al. Among authors: tolar m. Alzheimers Dement (N Y). 2024 Aug 13;10(3):e12498. doi: 10.1002/trc2.12498. eCollection 2024 Jul-Sep. Alzheimers Dement (N Y). 2024. PMID: 39144121 Free PMC article.
Point of view: Challenges in implementation of new immunotherapies for Alzheimer's disease.
Aye S, Johansson G, Hock C, Lannfelt L, Sims JR, Blennow K, Frederiksen KS, Graff C, Molinuevo JL, Scheltens P, Palmqvist S, Schöll M, Wimo A, Kivipelto M, Handels R, Frölich L, Zilka N, Tolar M, Johannsen P, Jönsson L, Winblad B. Aye S, et al. Among authors: tolar m. J Prev Alzheimers Dis. 2025 Jan;12(1):100022. doi: 10.1016/j.tjpad.2024.100022. Epub 2025 Jan 1. J Prev Alzheimers Dis. 2025. PMID: 39800469 Free PMC article.
54 results