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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 2
1977 1
1980 2
1981 4
1983 2
1984 2
1985 2
1986 2
1993 1
1999 1
2000 1
2006 1
2007 2
2009 1
2010 1
2011 2
2012 4
2013 4
2014 4
2015 5
2016 8
2017 3
2018 3
2019 3
2020 3
2021 5
2022 7
2023 3
2024 1
2025 4
2026 0

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77 results

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Page 1
Effectiveness of a Long-term Home-Based Exercise Training Program in Patients With COPD After Pulmonary Rehabilitation: A Multicenter Randomized Controlled Trial.
Frei A, Radtke T, Dalla Lana K, Brun P, Sigrist T, Spielmanns M, Beyer S, Riegler TF, Büsching G, Spielmanns S, Kunz R, Cerini T, Braun J, Tomonaga Y, Serra-Burriel M, Polhemus A, Puhan MA. Frei A, et al. Among authors: tomonaga y. Chest. 2022 Dec;162(6):1277-1286. doi: 10.1016/j.chest.2022.07.026. Epub 2022 Aug 8. Chest. 2022. PMID: 35952766 Free article. Clinical Trial.
Nonregistration, Discontinuation, and Nonpublication of Randomized Trials: A Systematic Review.
Speich B, Taji Heravi A, Schönenberger CM, Hausheer L, Gryaznov D, Busse JW, Covino M, Lohner S, Chiaborelli M, Schwenke JM, Ramirez Zegarra R, Saccilotto R, Hüllstrung JM, von Elm E, Agarwal A, Hirt J, Mall D, Amstutz A, Epp S, Mertz D, Blümle A, von Niederhäusern B, Odutayo A, Griessbach AN, Hopewell S, Briel M; ASPIRE Study Group. Speich B, et al. JAMA Netw Open. 2025 Sep 2;8(9):e2524440. doi: 10.1001/jamanetworkopen.2025.24440. JAMA Netw Open. 2025. PMID: 40899933 Free PMC article.
Metaresearch on patient-reported outcomes in trial protocols and results publications suggested large outcome reporting bias.
Taji Heravi A, Gryaznov D, Busse JW, Schönenberger CM, von Niederhäusern B, Hausheer L, Covino M, Schwenke JM, Epp S, Griessbach A, Chiaborelli M, Agarwal A, Lohner S, Hirt J, Schandelmaier S, Egli SB, Makhele MA, Amstutz A, Mertz D, Blümle A, von Elm E, Saccilotto R, Odutayo A, Hopewell S, Speich B, Briel M; Adherence to SPIRIT Recommendations (ASPIRE) Study Group. Taji Heravi A, et al. J Clin Epidemiol. 2025 Sep;185:111822. doi: 10.1016/j.jclinepi.2025.111822. Epub 2025 May 9. J Clin Epidemiol. 2025. PMID: 40349736 Free article.
Reliability of Trial Information Across Registries for Trials With Multiple Registrations: A Systematic Review.
Speich B, Gloy VL, Klatte K, Gryaznov D, Taji Heravi A, Ghosh N, Marian IR, Lee H, Mansouri A, Lohner S, Saccilotto R, Nury E, Chan AW, Blümle A, Odutayo A, Hopewell S, Briel M; Adherence to Spirit Recommendations (ASPIRE) Study Group. Speich B, et al. JAMA Netw Open. 2021 Nov 1;4(11):e2128898. doi: 10.1001/jamanetworkopen.2021.28898. JAMA Netw Open. 2021. PMID: 34724557 Free PMC article.
An analysis of protocols and publications suggested that most discontinuations of clinical trials were not based on preplanned interim analyses or stopping rules.
Stegert M, Kasenda B, von Elm E, You JJ, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Briel M; DISCO study group. Stegert M, et al. Among authors: tomonaga y. J Clin Epidemiol. 2016 Jan;69:152-60. doi: 10.1016/j.jclinepi.2015.05.023. Epub 2015 Jun 4. J Clin Epidemiol. 2016. PMID: 26361993 Review.
77 results