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Page 1
Signal peptide mimicry primes Sec61 for client-selective inhibition.
Rehan S, Tranter D, Sharp PP, Craven GB, Lowe E, Anderl JL, Muchamuel T, Abrishami V, Kuivanen S, Wenzell NA, Jennings A, Kalyanaraman C, Strandin T, Javanainen M, Vapalahti O, Jacobson MP, McMinn D, Kirk CJ, Huiskonen JT, Taunton J, Paavilainen VO. Rehan S, et al. Among authors: tranter d. Nat Chem Biol. 2023 Sep;19(9):1054-1062. doi: 10.1038/s41589-023-01326-1. Epub 2023 May 11. Nat Chem Biol. 2023. PMID: 37169961 Free PMC article.
Goodbye.
Tranter D. Tranter D. Pharm Sci Technol Today. 2000 Dec 1;3(12):431. doi: 10.1016/s1461-5347(00)00324-2. Pharm Sci Technol Today. 2000. PMID: 11116204 No abstract available.
Lipid Scrambling Pathways in the Sec61 Translocon Complex.
Javanainen M, Šimek J, Tranter D, O'Keefe S, Karki S, Biriukov D, Šachl R, Paavilainen VO. Javanainen M, et al. Among authors: tranter d. J Am Chem Soc. 2025 May 14;147(19):15970-15984. doi: 10.1021/jacs.4c11142. Epub 2025 May 5. J Am Chem Soc. 2025. PMID: 40325981 Free PMC article.
Monitor editorship.
Tranter D. Tranter D. Pharm Sci Technol Today. 2000 Dec 1;3(12):431. doi: 10.1016/s1461-5347(00)00325-4. Pharm Sci Technol Today. 2000. PMID: 11116203 No abstract available.
Monitor Editorship.
Tranter D. Tranter D. Drug Discov Today. 2000 Dec 1;5(12):569. doi: 10.1016/s1359-6446(00)01607-x. Drug Discov Today. 2000. PMID: 11102857 No abstract available.
Molecular view of ER membrane remodeling by the Sec61/TRAP translocon.
Karki S, Javanainen M, Rehan S, Tranter D, Kellosalo J, Huiskonen JT, Happonen L, Paavilainen V. Karki S, et al. Among authors: tranter d. EMBO Rep. 2023 Dec 6;24(12):e57910. doi: 10.15252/embr.202357910. Epub 2023 Nov 20. EMBO Rep. 2023. PMID: 37983950 Free PMC article.
Preclinical characterization of novel multi-client inhibitors of Sec61 with broad antitumor activity.
Lowe E, Anderl JL, Bade D, Delgado-Martin C, Dong C, Fan RA, Fang Y, Jiang J, Johnson HWB, Kempema A, McGilvray P, McMinn D, Millare B, Muchamuel T, Poweleit N, Qian Y, Rehan S, Scapin G, Sugahara A, Tranter D, Tuch B, Wang J, Wang L, Whang JA, Zuno-Mitchell P, Paavilainen VO, Park E, Taunton J, Kirk CJ, Anand NK. Lowe E, et al. Among authors: tranter d. J Pharmacol Exp Ther. 2025 Aug;392(8):103634. doi: 10.1016/j.jpet.2025.103634. Epub 2025 Jun 14. J Pharmacol Exp Ther. 2025. PMID: 40669140 Free article.
Snapshots of actin and tubulin folding inside the TRiC chaperonin.
Kelly JJ, Tranter D, Pardon E, Chi G, Kramer H, Happonen L, Knee KM, Janz JM, Steyaert J, Bulawa C, Paavilainen VO, Huiskonen JT, Yue WW. Kelly JJ, et al. Among authors: tranter d. Nat Struct Mol Biol. 2022 May;29(5):420-429. doi: 10.1038/s41594-022-00755-1. Epub 2022 Apr 21. Nat Struct Mol Biol. 2022. PMID: 35449234 Free PMC article.
G Protein-Coupled Receptors Contain Two Conserved Packing Clusters.
Sanchez-Reyes OB, Cooke ALG, Tranter DB, Rashid D, Eilers M, Reeves PJ, Smith SO. Sanchez-Reyes OB, et al. Among authors: tranter db. Biophys J. 2017 Jun 6;112(11):2315-2326. doi: 10.1016/j.bpj.2017.04.051. Biophys J. 2017. PMID: 28591604 Free PMC article.
Ipomoeassin F Binds Sec61α to Inhibit Protein Translocation.
Zong G, Hu Z, O'Keefe S, Tranter D, Iannotti MJ, Baron L, Hall B, Corfield K, Paatero AO, Henderson MJ, Roboti P, Zhou J, Sun X, Govindarajan M, Rohde JM, Blanchard N, Simmonds R, Inglese J, Du Y, Demangel C, High S, Paavilainen VO, Shi WQ. Zong G, et al. Among authors: tranter d. J Am Chem Soc. 2019 May 29;141(21):8450-8461. doi: 10.1021/jacs.8b13506. Epub 2019 May 15. J Am Chem Soc. 2019. PMID: 31059257 Free PMC article.
32 results