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Page 1
Comprehensive analysis of kinase inhibitor selectivity.
Davis MI, Hunt JP, Herrgard S, Ciceri P, Wodicka LM, Pallares G, Hocker M, Treiber DK, Zarrinkar PP. Davis MI, et al. Among authors: treiber dk. Nat Biotechnol. 2011 Oct 30;29(11):1046-51. doi: 10.1038/nbt.1990. Nat Biotechnol. 2011. PMID: 22037378
A quantitative analysis of kinase inhibitor selectivity.
Karaman MW, Herrgard S, Treiber DK, Gallant P, Atteridge CE, Campbell BT, Chan KW, Ciceri P, Davis MI, Edeen PT, Faraoni R, Floyd M, Hunt JP, Lockhart DJ, Milanov ZV, Morrison MJ, Pallares G, Patel HK, Pritchard S, Wodicka LM, Zarrinkar PP. Karaman MW, et al. Among authors: treiber dk. Nat Biotechnol. 2008 Jan;26(1):127-32. doi: 10.1038/nbt1358. Nat Biotechnol. 2008. PMID: 18183025
Donated chemical probes for open science.
Müller S, Ackloo S, Arrowsmith CH, Bauser M, Baryza JL, Blagg J, Böttcher J, Bountra C, Brown PJ, Bunnage ME, Carter AJ, Damerell D, Dötsch V, Drewry DH, Edwards AM, Edwards J, Elkins JM, Fischer C, Frye SV, Gollner A, Grimshaw CE, IJzerman A, Hanke T, Hartung IV, Hitchcock S, Howe T, Hughes TV, Laufer S, Li VM, Liras S, Marsden BD, Matsui H, Mathias J, O'Hagan RC, Owen DR, Pande V, Rauh D, Rosenberg SH, Roth BL, Schneider NS, Scholten C, Singh Saikatendu K, Simeonov A, Takizawa M, Tse C, Thompson PR, Treiber DK, Viana AY, Wells CI, Willson TM, Zuercher WJ, Knapp S, Mueller-Fahrnow A. Müller S, et al. Among authors: treiber dk. Elife. 2018 Apr 20;7:e34311. doi: 10.7554/eLife.34311. Elife. 2018. PMID: 29676732 Free PMC article.
Dual kinase-bromodomain inhibitors for rationally designed polypharmacology.
Ciceri P, Müller S, O'Mahony A, Fedorov O, Filippakopoulos P, Hunt JP, Lasater EA, Pallares G, Picaud S, Wells C, Martin S, Wodicka LM, Shah NP, Treiber DK, Knapp S. Ciceri P, et al. Among authors: treiber dk. Nat Chem Biol. 2014 Apr;10(4):305-12. doi: 10.1038/nchembio.1471. Epub 2014 Mar 2. Nat Chem Biol. 2014. PMID: 24584101 Free PMC article.
Beyond kinetic traps in RNA folding.
Treiber DK, Williamson JR. Treiber DK, et al. Curr Opin Struct Biol. 2001 Jun;11(3):309-14. doi: 10.1016/s0959-440x(00)00206-2. Curr Opin Struct Biol. 2001. PMID: 11406379 Review.
Exposing the kinetic traps in RNA folding.
Treiber DK, Williamson JR. Treiber DK, et al. Curr Opin Struct Biol. 1999 Jun;9(3):339-45. doi: 10.1016/S0959-440X(99)80045-1. Curr Opin Struct Biol. 1999. PMID: 10361090 Review.
Ins and outs of kinase DFG motifs.
Treiber DK, Shah NP. Treiber DK, et al. Chem Biol. 2013 Jun 20;20(6):745-6. doi: 10.1016/j.chembiol.2013.06.001. Chem Biol. 2013. PMID: 23790484
40 results