Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 1994 Jun 21;91(13):5927-31.
doi: 10.1073/pnas.91.13.5927.

Inactivation of the Podospora anserina vegetative incompatibility locus het-c, whose product resembles a glycolipid transfer protein, drastically impairs ascospore production

S Saupe  1 , C Descamps, B Turcq, J Bégueret
Affiliations
Comparative Study

Inactivation of the Podospora anserina vegetative incompatibility locus het-c, whose product resembles a glycolipid transfer protein, drastically impairs ascospore production

S Saupe et al. Proc Natl Acad Sci U S A. .

Abstract

The het-c locus contains different alleles that elicit nonallelic vegetative incompatibility through specific interactions with alleles of the unlinked loci het-e and het-d. The het-c2 allele has been cloned. It encodes a 208-amino acid polypeptide that is similar to a glycolipid transfer protein purified from pig brain. Disruption of this gene drastically impairs ascospore production in homozygous crosses, and some mutants exhibit abnormal branching of apical hyphae. The protein encoded by het-c2 is essential in the biology of the fungus and may be involved in cell-wall biosynthesis.

PubMed Disclaimer

References

    1. Gene. 1988 Jul 15;67(1):31-40 - PubMed
    1. Mol Gen Genet. 1976 Mar 22;144(2):191-7 - PubMed
    1. Yeast. 1986 Dec;2(4):229-36 - PubMed
    1. J Biol Chem. 1990 Jun 15;265(17):9634-7 - PubMed
    1. Cell. 1993 Sep 10;74(5):919-28 - PubMed

Publication types

Associated data