Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1998 Mar;18(3):243-50.
doi: 10.1038/ng0398-243.

Distribution of olfactory receptor genes in the human genome

S Rouquier  1 , S Taviaux, B J Trask, V Brand-Arpon, G van den Engh, J Demaille, D Giorgi
Affiliations

Distribution of olfactory receptor genes in the human genome

S Rouquier et al. Nat Genet. 1998 Mar.

Erratum in

  • Nat Genet 1998 May;19(1):102

Abstract

We demonstrate that members of the olfactory receptor (OR) gene family are distributed on all but a few human chromosomes. Through FISH analysis, we show that OR sequences reside at more than 25 locations in the human genome. Their distribution is biased for terminal bands. Flow-sorted chromosomes were used to isolate 87 OR sequences derived from 16 chromosomes. Their sequence-relationships are indicative of the inter- and intrachromosomal duplications responsible for OR family expansion. The human genome has accumulated a striking number of dysfunctional copies: 72% of the sequences are pseudogenes. ORF-containing sequences predominate on chromosomes 7, 16 and 17.

PubMed Disclaimer

Publication types

Associated data

LinkOut - more resources