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Year Number of Results
1968 1
2001 1
2008 1
2010 1
2012 1
2013 1
2014 4
2015 3
2016 3
2017 7
2018 7
2019 11
2020 12
2021 13
2022 15
2023 19
2024 18
2025 22

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130 results

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Page 1
Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma.
Au L, Hatipoglu E, Robert de Massy M, Litchfield K, Beattie G, Rowan A, Schnidrig D, Thompson R, Byrne F, Horswell S, Fotiadis N, Hazell S, Nicol D, Shepherd STC, Fendler A, Mason R, Del Rosario L, Edmonds K, Lingard K, Sarker S, Mangwende M, Carlyle E, Attig J, Joshi K, Uddin I, Becker PD, Sunderland MW, Akarca A, Puccio I, Yang WW, Lund T, Dhillon K, Vasquez MD, Ghorani E, Xu H, Spencer C, López JI, Green A, Mahadeva U, Borg E, Mitchison M, Moore DA, Proctor I, Falzon M, Pickering L, Furness AJS, Reading JL, Salgado R, Marafioti T, Jamal-Hanjani M; PEACE Consortium; Kassiotis G, Chain B, Larkin J, Swanton C, Quezada SA, Turajlic S; TRACERx Renal Consortium. Au L, et al. Among authors: uddin i. Cancer Cell. 2021 Nov 8;39(11):1497-1518.e11. doi: 10.1016/j.ccell.2021.10.001. Epub 2021 Oct 28. Cancer Cell. 2021. PMID: 34715028 Free PMC article.
Tissue CD14+CD8+ T cells reprogrammed by myeloid cells and modulated by LPS.
Pallett LJ, Swadling L, Diniz M, Maini AA, Schwabenland M, Gasull AD, Davies J, Kucykowicz S, Skelton JK, Thomas N, Schmidt NM, Amin OE, Gill US, Stegmann KA, Burton AR, Stephenson E, Reynolds G, Whelan M, Sanchez J, de Maeyer R, Thakker C, Suveizdyte K, Uddin I, Ortega-Prieto AM, Grant C, Froghi F, Fusai G, Lens S, Pérez-Del-Pulgar S, Al-Akkad W, Mazza G, Noursadeghi M, Akbar A, Kennedy PTF, Davidson BR, Prinz M, Chain BM, Haniffa M, Gilroy DW, Dorner M, Bengsch B, Schurich A, Maini MK. Pallett LJ, et al. Among authors: uddin i. Nature. 2023 Feb;614(7947):334-342. doi: 10.1038/s41586-022-05645-6. Epub 2023 Jan 25. Nature. 2023. PMID: 36697826
Phenotypic heterogeneity and plasticity in colorectal cancer metastasis.
Ogden S, Metic N, Leylek O, Smith EA, Berner AM, Baker AM, Uddin I, Buzzetti M, Gerlinger M; Cancer Tissue Bank; Graham T, Kocher HM, Efremova M. Ogden S, et al. Among authors: uddin i. Cell Genom. 2025 Jul 9;5(7):100881. doi: 10.1016/j.xgen.2025.100881. Epub 2025 May 19. Cell Genom. 2025. PMID: 40393458 Free PMC article.
Aberrant basal cell clonal dynamics shape early lung carcinogenesis.
Gómez-López S, Alhendi ASN, Przybilla MJ, Bordeu I, Whiteman ZE, Butler T, Rouhani MJ, Kalinke L, Uddin I, Otter KEJ, Chandrasekharan DP, Lebrusant-Fernandez M, Shurr AYL, Durrenberger PF, Moore DA, Falzon M, Reading JL, Martincorena I, Simons BD, Campbell PJ, Janes SM. Gómez-López S, et al. Among authors: uddin i. Science. 2025 Jun 12;388(6752):eads9145. doi: 10.1126/science.ads9145. Epub 2025 Jun 12. Science. 2025. PMID: 40310937 Free PMC article.
Clonal driver neoantigen loss under EGFR TKI and immune selection pressures.
Al Bakir M, Reading JL, Gamble S, Rosenthal R, Uddin I, Rowan A, Przewrocka J, Rogers A, Wong YNS, Bentzen AK, Veeriah S, Ward S, Garnett AT, Kalavakur P, Martínez-Ruiz C, Puttick C, Huebner A, Cook DE, Moore DA, Abbosh C, Hiley CT, Naceur-Lombardelli C, Watkins TBK, Petkovic M, Schwarz RF, Gálvez-Cancino F, Litchfield K, Meldgaard P, Sorensen BS, Madsen LB, Jäger D, Forster MD, Arkenau T, Domingo-Vila C, Tree TIM, Kadivar M, Hadrup SR, Chain B, Quezada SA, McGranahan N, Swanton C. Al Bakir M, et al. Among authors: uddin i. Nature. 2025 Mar;639(8056):1052-1059. doi: 10.1038/s41586-025-08586-y. Epub 2025 Feb 19. Nature. 2025. PMID: 39972134 Free PMC article.
The T cell differentiation landscape is shaped by tumour mutations in lung cancer.
Ghorani E, Reading JL, Henry JY, Massy MR, Rosenthal R, Turati V, Joshi K, Furness AJS, Ben Aissa A, Saini SK, Ramskov S, Georgiou A, Sunderland MW, Wong YNS, Mucha MV, Day W, Galvez-Cancino F, Becker PD, Uddin I, Oakes T, Ismail M, Ronel T, Woolston A, Jamal-Hanjani M, Veeriah S, Birkbak NJ, Wilson GA, Litchfield K, Conde L, Guerra-Assunção JA, Blighe K, Biswas D, Salgado R, Lund T, Bakir MA, Moore DA, Hiley CT, Loi S, Sun Y, Yuan Y, AbdulJabbar K, Turajilic S, Herrero J, Enver T, Hadrup SR, Hackshaw A, Peggs KS, McGranahan N, Chain B; TRACERx Consortium; Swanton C, Quezada SA. Ghorani E, et al. Among authors: uddin i. Nat Cancer. 2020 May;1(5):546-561. doi: 10.1038/s43018-020-0066-y. Epub 2020 May 22. Nat Cancer. 2020. PMID: 32803172 Free PMC article.
Regulatory T cell depletion promotes myeloid cell activation and glioblastoma response to anti-PD1 and tumor-targeting antibodies.
Galvez-Cancino F, Navarrete M, Beattie G, Puccio S, Conde-Gallastegi E, Foster K, Morris Y, Sahwangarrom T, Karagianni D, Liu J, Lee AJX, Garyfallos DA, Simpson AP, Mastrokalos GT, Nannini F, Costoya C, Anantharam V, Cianciotti BC, Bradley L, Garcia-Diaz C, Clements M, Shroff A, Vahid Dastjerdi F, Rota EM, Sheraz S, Bentham R, Uddin I, Walczak H, Lladser A, Reading JL, Chester KA, Pule MA, Brennan PM, Marguerat S, Parrinello S, Peggs KS, McGranahan N, Lugli E, Litchfield K, Pollard SM, Quezada SA. Galvez-Cancino F, et al. Among authors: uddin i. Immunity. 2025 May 13;58(5):1236-1253.e8. doi: 10.1016/j.immuni.2025.03.021. Epub 2025 Apr 24. Immunity. 2025. PMID: 40280128 Free article.
Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer.
Joshi K, de Massy MR, Ismail M, Reading JL, Uddin I, Woolston A, Hatipoglu E, Oakes T, Rosenthal R, Peacock T, Ronel T, Noursadeghi M, Turati V, Furness AJS, Georgiou A, Wong YNS, Ben Aissa A, Sunderland MW, Jamal-Hanjani M, Veeriah S, Birkbak NJ, Wilson GA, Hiley CT, Ghorani E, Guerra-Assunção JA, Herrero J, Enver T, Hadrup SR, Hackshaw A, Peggs KS, McGranahan N, Swanton C; TRACERx consortium; Quezada SA, Chain B. Joshi K, et al. Among authors: uddin i. Nat Med. 2019 Oct;25(10):1549-1559. doi: 10.1038/s41591-019-0592-2. Epub 2019 Oct 7. Nat Med. 2019. PMID: 31591606 Free PMC article.
Axonal injury is a targetable driver of glioblastoma progression.
Clements M, Tang W, Florjanic Baronik Z, Simpson Ragdale H, Oria R, Volteras D, White IJ, Beattie G, Uddin I, Lenn T, Lindsay R, Castro Devesa S, Karamched SR, Lythgoe MF, Shahrezaei V, Weaver VM, Sugisawa R, Roncaroli F, Marguerat S, Hill CS, Parrinello S. Clements M, et al. Among authors: uddin i. Nature. 2025 Aug 20. doi: 10.1038/s41586-025-09411-2. Online ahead of print. Nature. 2025. PMID: 40836081
130 results