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Page 1
Metastasis and Immune Evasion from Extracellular cGAMP Hydrolysis.
Li J, Duran MA, Dhanota N, Chatila WK, Bettigole SE, Kwon J, Sriram RK, Humphries MP, Salto-Tellez M, James JA, Hanna MG, Melms JC, Vallabhaneni S, Litchfield K, Usaite I, Biswas D, Bareja R, Li HW, Martin ML, Dorsaint P, Cavallo JA, Li P, Pauli C, Gottesdiener L, DiPardo BJ, Hollmann TJ, Merghoub T, Wen HY, Reis-Filho JS, Riaz N, Su SM, Kalbasi A, Vasan N, Powell SN, Wolchok JD, Elemento O, Swanton C, Shoushtari AN, Parkes EE, Izar B, Bakhoum SF. Li J, et al. Among authors: usaite i. Cancer Discov. 2021 May;11(5):1212-1227. doi: 10.1158/2159-8290.CD-20-0387. Epub 2020 Dec 28. Cancer Discov. 2021. PMID: 33372007 Free PMC article.
Subclonal immune evasion in non-small cell lung cancer.
Dijkstra KK, Vendramin R, Karagianni D, Witsen M, Gálvez-Cancino F, Hill MS, Foster KA, Barbè V, Angelova M, Hynds RE, Pearce DR, Martínez-Ruiz C, Black JRM, Huebner A, Pich O, Rowan A, Augustine M, Puttick C, Moore DA, Liu LL, Saghafinia S, van de Haar J, Veeriah S, Naceur-Lombardelli C, Toncheva A, Bola SK, Hiley CT, Jamal-Hanjani M, McGranahan N, Litchfield K, Reading JL, Chain B; TRACERx consortium; Quezada SA, Voest EE, Swanton C. Dijkstra KK, et al. Cancer Cell. 2025 Jul 1:S1535-6108(25)00262-4. doi: 10.1016/j.ccell.2025.06.012. Online ahead of print. Cancer Cell. 2025. PMID: 40614739 Free article.
MHC Hammer reveals genetic and non-genetic HLA disruption in cancer evolution.
Puttick C, Jones TP, Leung MM, Galvez-Cancino F, Liu J, Varas-Godoy M, Rowan A, Pich O, Martinez-Ruiz C, Bentham R, Dijkstra KK, Black JRM, Rosenthal R, Kanu N, Litchfield K, Salgado R, Moore DA, Van Loo P, Jamal-Hanjani M, Quezada SA; TRACERx Consortium; Swanton C, McGranahan N. Puttick C, et al. Nat Genet. 2024 Oct;56(10):2121-2131. doi: 10.1038/s41588-024-01883-8. Epub 2024 Oct 2. Nat Genet. 2024. PMID: 39358601 Free PMC article.
A local human Vδ1 T cell population is associated with survival in nonsmall-cell lung cancer.
Wu Y, Biswas D, Usaite I, Angelova M, Boeing S, Karasaki T, Veeriah S, Czyzewska-Khan J, Morton C, Joseph M, Hessey S, Reading J, Georgiou A, Al-Bakir M; TRACERx Consortium; McGranahan N, Jamal-Hanjani M, Hackshaw A, Quezada SA, Hayday AC, Swanton C. Wu Y, et al. Among authors: usaite i. Nat Cancer. 2022 Jun;3(6):696-709. doi: 10.1038/s43018-022-00376-z. Epub 2022 May 30. Nat Cancer. 2022. PMID: 35637401 Free PMC article.
ImmuneLENS characterizes systemic immune dysregulation in aging and cancer.
Bentham R, Jones TP, Black JRM, Martinez-Ruiz C, Dietzen M, Litovchenko M, Thol K, Watkins TBK, Bailey C, Pich O, Zhang Z, Van Loo P; TRACERx Consortium; Genomics England Consortium; Swanton C, McGranahan N. Bentham R, et al. Nat Genet. 2025 Mar;57(3):694-705. doi: 10.1038/s41588-025-02086-5. Epub 2025 Feb 18. Nat Genet. 2025. PMID: 39966644 Free PMC article.
TRACERx analysis identifies a role for FAT1 in regulating chromosomal instability and whole-genome doubling via Hippo signalling.
Lu WT, Zalmas LP, Bailey C, Black JRM, Martinez-Ruiz C, Pich O, Gimeno-Valiente F, Usaite I, Magness A, Thol K, Webber TA, Jiang M, Saunders RE, Liu YH, Biswas D, Ige EO, Aerne B, Grönroos E, Venkatesan S, Stavrou G, Karasaki T, Al Bakir M, Renshaw M, Xu H, Schneider-Luftman D, Sharma N, Tovini L; TRACERx Consortium; Jamal-Hanjani M, McClelland SE, Litchfield K, Birkbak NJ, Howell M, Tapon N, Fugger K, McGranahan N, Bartek J, Kanu N, Swanton C. Lu WT, et al. Among authors: usaite i. Nat Cell Biol. 2025 Jan;27(1):154-168. doi: 10.1038/s41556-024-01558-w. Epub 2024 Dec 30. Nat Cell Biol. 2025. PMID: 39738653 Free PMC article.
Prospective validation of ORACLE, a clonal expression biomarker associated with survival of patients with lung adenocarcinoma.
Biswas D, Liu YH, Herrero J, Wu Y, Moore DA, Karasaki T, Grigoriadis K, Lu WT, Veeriah S, Naceur-Lombardelli C, Magno N, Ward S, Frankell AM, Hill MS, Colliver E, de Carné Trécesson S, East P, Malhi A, Snell DM, O'Neill O, Leonce D, Mattsson J, Lindberg A, Micke P, Moldvay J, Megyesfalvi Z, Dome B, Fillinger J, Nicod J, Downward J, Szallasi Z; TRACERx Consortium; Hackshaw A, Jamal-Hanjani M, Kanu N, Birkbak NJ, Swanton C. Biswas D, et al. Nat Cancer. 2025 Jan;6(1):86-101. doi: 10.1038/s43018-024-00883-1. Epub 2025 Jan 9. Nat Cancer. 2025. PMID: 39789179 Free PMC article.
DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution.
Gimeno-Valiente F, Castignani C, Larose Cadieux E, Mensah NE, Liu X, Chen K, Chervova O, Karasaki T, Weeden CE, Richard C, Lai S, Martínez-Ruiz C, Lim EL, Frankell AM, Watkins TBK, Stavrou G, Usaite I, Lu WT, Marinelli D, Saghafinia S, Wilson GA, Dhami P, Vaikkinen H, Steif J, Veeriah S, Hynds RE, Hirst M, Hiley C, Feber A, Deniz Ö, Jamal-Hanjani M, McGranahan N; TRACERx Consortium; Beck S, Demeulemeester J, Tanić M, Swanton C, Van Loo P, Kanu N. Gimeno-Valiente F, et al. Among authors: usaite i. Nat Genet. 2025 Sep;57(9):2226-2237. doi: 10.1038/s41588-025-02307-x. Epub 2025 Sep 10. Nat Genet. 2025. PMID: 40931149 Free PMC article.
Quantifying the impact of immunotherapy on RNA dynamics in cancer.
Usaite I, Biswas D, Dijkstra K, Watkins TB, Pich O, Puttick C, Angelova M, Thakkar K, Hiley C, Birkbak N, Kok M, Zaccaria S, Wu Y, Litchfield K, Swanton C, Kanu N. Usaite I, et al. J Immunother Cancer. 2023 Nov;11(11):e007870. doi: 10.1136/jitc-2023-007870. J Immunother Cancer. 2023. PMID: 37914385 Free PMC article.
11 results