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Page 1
Plasticity of the mammalian integrated stress response.
Chen CW, Papadopoli D, Szkop KJ, Guan BJ, Alzahrani M, Wu J, Jobava R, Asraf MM, Krokowski D, Vourekas A, Merrick WC, Komar AA, Koromilas AE, Gorospe M, Payea MJ, Wang F, Clayton BLL, Tesar PJ, Schaffer A, Miron A, Bederman I, Jankowsky E, Vogel C, Valášek LS, Dinman JD, Zhang Y, Tirosh B, Larsson O, Topisirovic I, Hatzoglou M. Chen CW, et al. Among authors: valasek ls. Nature. 2025 May;641(8065):1319-1328. doi: 10.1038/s41586-025-08794-6. Epub 2025 Mar 26. Nature. 2025. PMID: 40140574 Free PMC article.
Stops making sense - For the people?
Valášek LS, Lukeš J, Paris Z. Valášek LS, et al. Clin Transl Med. 2023 May;13(5):e1270. doi: 10.1002/ctm2.1270. Clin Transl Med. 2023. PMID: 37203266 Free PMC article. No abstract available.
Translon: a single term for translated regions.
Świrski MI, Tierney JAS, Albà MM, Andreev DE, Aspden JL, Atkins JF, Bassani-Sternberg M, Berry MJ, Biffo S, Boris-Lawrie K, Borodovsky M, Brierley I, Brook M, Brunet MA, Bujnicki JM, Caliskan N, Calviello L, Carvunis AR, Cate JHD, Cenik C, Chang KY, Chen Y, Chothani S, Choudhary JS, Clark PL, Clauwaert J, Cooley L, Dassi E, Dean K, Diaz JJ, Dieterich C, Dikstein R, Dinman JD, Dmitriev SE, Dontsova OA, Dunham CM, Eswarappa SM, Farabaugh PJ, Faridi P, Fierro-Monti I, Firth AE, Gatfield D, Gebauer F, Gelfand MS, Gray NK, Green R, Hill CH, Hou YM, Hübner N, Ignatova Z, Ivanov P, Iwasaki S, Johnson R, Jomaa A, Jovanovic M, Jungreis I, Kellis M, Kieft JS, Kochetov AV, Koonin EV, Korostelev AA, Kufel J, Kulakovskiy IV, Kurian L, Lafontaine DLJ, Larsson O, Loughran G, Lukeš J, Mariotti M, Martens-Uzunova ES, Martinez TF, Matsumoto A, McManus J, Medenbach J, Melnikov SV, Menschaert G, Merchante C, Mikl M, Miller WA, Mühlemann O, Namy O, Nedialkova DD, Nosek J, Orchard S, Ozretić P, Pertea M, Pervouchine DD, Romão L, Ron D, Roucou X, Rubtsova MP, Ruiz-Orera J, Saghatelian A, Salzberg SL, Seale LA, Seoighe C, Sergiev PV, Shah P, Shirokikh N, Slavoff SA, Sonenberg N, Stasevich TJ, Szczesny RJ… See abstract for full author list ➔ Świrski MI, et al. Among authors: valasek ls. Nat Methods. 2025 Oct;22(10):2002-2006. doi: 10.1038/s41592-025-02810-3. Nat Methods. 2025. PMID: 40890551 No abstract available.
Short tRNA anticodon stem and mutant eRF1 allow stop codon reassignment.
Kachale A, Pavlíková Z, Nenarokova A, Roithová A, Durante IM, Miletínová P, Záhonová K, Nenarokov S, Votýpka J, Horáková E, Ross RL, Yurchenko V, Beznosková P, Paris Z, Valášek LS, Lukeš J. Kachale A, et al. Among authors: valasek ls. Nature. 2023 Jan;613(7945):751-758. doi: 10.1038/s41586-022-05584-2. Epub 2023 Jan 11. Nature. 2023. PMID: 36631608
Stem-loop-induced ribosome queuing in the uORF2/ATF4 overlap fine-tunes stress-induced human ATF4 translational control.
Smirnova AM, Hronová V, Mohammad MP, Herrmannová A, Gunišová S, Petráčková D, Halada P, Coufal Š, Świrski M, Rendleman J, Jendruchová K, Hatzoglou M, Beznosková P, Vogel C, Valášek LS. Smirnova AM, et al. Among authors: valasek ls. Cell Rep. 2024 Apr 23;43(4):113976. doi: 10.1016/j.celrep.2024.113976. Epub 2024 Mar 19. Cell Rep. 2024. PMID: 38507410 Free PMC article.
Ribosomal A-site interactions with near-cognate tRNAs drive stop codon readthrough.
Čapková Pavlíková Z, Miletínová P, Roithová A, Pospíšilová K, Záhonová K, Kachale A, Becker T, Durante IM, Lukeš J, Paris Z, Beznosková P, Valášek LS. Čapková Pavlíková Z, et al. Among authors: valasek ls. Nat Struct Mol Biol. 2025 Apr;32(4):662-674. doi: 10.1038/s41594-024-01450-z. Epub 2025 Jan 13. Nat Struct Mol Biol. 2025. PMID: 39806023
55 results