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Page 1
Prothrombin Complex Concentrate vs Frozen Plasma for Coagulopathic Bleeding in Cardiac Surgery: The FARES-II Multicenter Randomized Clinical Trial.
Karkouti K, Callum JL, Bartoszko J, Tanaka KA, Knaub S, Brar S, Ghadimi K, Rochon A, Mullane D, Couture EJ, Lin Y, Harle C, Zeller M, Tran DTT, Solomon C, Rao V, Law M, Butt AL, Chen EP, Martins MR, Saha T, Shih AW, Vézina MC, Moussa F, Pereira Cezar Zamper R, Syed S, Buyukdere H, Werner S, Grewal D, Wong D, Vandyck KB, Tanzola R, Hughes B, Royer O, Wong S, Levy JH; FARES-II Study Group. Karkouti K, et al. Among authors: vandyck kb. JAMA. 2025 May 27;333(20):1781-1792. doi: 10.1001/jama.2025.3501. JAMA. 2025. PMID: 40156829 Free PMC article. Clinical Trial.
A Randomized Trial of Acute Normovolemic Hemodilution in Cardiac Surgery.
Monaco F, Lei C, Bonizzoni MA, Efremov S, Morselli F, Guarracino F, Giardina G, Arangino C, Pontillo D, Vitiello M, Belletti A, Ajello V, Licheri M, Nigro Neto C, Barucco G, Bukamal NA, Faustini C, Mantovani LF, Oriani A, Santonocito C, Mucchetti M, Federici F, Gerli C, Porta S, Scandroglio AM, Zhang H, Pieri M, Osinsky R, Lazzari S, Leonova E, Calabrò MG, Amitrano D, Turi S, Prati P, Fresilli S, D'Amico F, D'Andria Ursoleo J, Labanca R, Marmiere M, Pruna A, Scquizzato T, Kırali K, Monti G, Carmona MJC, Tanaka K, Likhvantsev V, Ti LK, Bove T, Paternoster G, Singh K, Gürcü ME, Lomivorotov V, Landoni G, Bellomo R, Zangrillo A; ANH Study Group. Monaco F, et al. N Engl J Med. 2025 Jul 31;393(5):450-460. doi: 10.1056/NEJMoa2504948. Epub 2025 Jun 12. N Engl J Med. 2025. PMID: 40503713 Clinical Trial.
Walking a Thin Line.
Vandyck K, Windrix C, Wyatt EC, Tanaka KA. Vandyck K, et al. J Cardiothorac Vasc Anesth. 2023 Jan;37(1):190-191. doi: 10.1053/j.jvca.2022.10.008. Epub 2022 Oct 13. J Cardiothorac Vasc Anesth. 2023. PMID: 36328925 No abstract available.
Management of Patients With Hemophilia Undergoing Cardiac Surgery.
Bolliger D, Vandyck K, Tanaka KA. Bolliger D, et al. Among authors: vandyck k. J Cardiothorac Vasc Anesth. 2022 Feb;36(2):539-541. doi: 10.1053/j.jvca.2021.11.022. Epub 2021 Nov 19. J Cardiothorac Vasc Anesth. 2022. PMID: 34933808 No abstract available.
Acute Normovolemic Hemodilution in Adult Cardiac Surgery.
Tanaka KA, Stewart KE, Vandyck KB, Burkhart HM, Garwe T, Kertai MD, Butt AL, Mazzeffi MA. Tanaka KA, et al. Among authors: vandyck kb. JAMA Surg. 2025 Sep 3:e253238. doi: 10.1001/jamasurg.2025.3238. Online ahead of print. JAMA Surg. 2025. PMID: 40900582
Discovery and Preclinical Profile of ALG-097558, a Pan-Coronavirus 3CLpro Inhibitor.
Bardiot D, McGowan DC, Gupta K, Deval J, Chang S, Jekle A, Liu C, Stevens S, Serebryany V, Tauchert MJ, Maskos K, Stoycheva AD, Ren S, Jaisinghani R, Faucher MO, Lin TI, Boland S, Chaltin P, Marchand A, Wuyts J, De Jonghe S, Jochmans D, Anugu S, Baloju V, Deta K, Welch M, Leyssen P, Neyts J, Laporte M, Abdelnabi R, Hu H, Zhang P, Le K, Chanda S, Smith DB, Raboisson P, Beigelman L, Symons JA, Blatt L, Vandyck K. Bardiot D, et al. Among authors: vandyck k. J Med Chem. 2025 Jul 10;68(13):13436-13454. doi: 10.1021/acs.jmedchem.5c00088. Epub 2025 Jun 30. J Med Chem. 2025. PMID: 40586480
Protocol for a phase 3, randomised, active-control study of four-factor prothrombin complex concentrate versus frozen plasma in bleeding adult cardiac surgery patients requiring coagulation factor replacement: the LEX-211 (FARES-II) trial.
Karkouti K, Callum J, Bartoszko J, Solomon C, Knaub S, Levy JH, Tanaka KA; FARES-II Study Group. Karkouti K, et al. BMJ Open. 2024 Aug 21;14(8):e091381. doi: 10.1136/bmjopen-2024-091381. BMJ Open. 2024. PMID: 39174056 Free PMC article.
54 results