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Page 1
Interferon gamma signaling drives cardiac metabolic rewiring.
Melika ET, Ashour D, Kim K, Nickel A, Arias-Loza P, Chen X, Arampatzi P, Srivastava M, Väth M, Cunha E, Kuhn M, Gasteiger G, Hofmann U, Higuchi T, Maack C, Frantz S, Karlstaedt A, Ramos GC. Melika ET, et al. Among authors: vath m. bioRxiv [Preprint]. 2025 Sep 7:2025.08.31.673391. doi: 10.1101/2025.08.31.673391. bioRxiv. 2025. PMID: 40950099 Free PMC article. Preprint.
Discovery of 3-hydroxy-4-cyano-isoquinolines as novel, potent, and selective inhibitors of human 11β-hydroxydehydrogenase 1 (11β-HSD1).
Wu SC, Yoon D, Chin J, van Kirk K, Seethala R, Golla R, He B, Harrity T, Kunselman LK, Morgan NN, Ponticiello RP, Taylor JR, Zebo R, Harper TW, Li W, Wang M, Zhang L, Sleczka BG, Nayeem A, Sheriff S, Camac DM, Morin PE, Everlof JG, Li YX, Ferraro CA, Kieltyka K, Shou W, Vath MB, Zvyaga TA, Gordon DA, Robl JA. Wu SC, et al. Among authors: vath mb. Bioorg Med Chem Lett. 2011 Nov 15;21(22):6693-8. doi: 10.1016/j.bmcl.2011.09.058. Epub 2011 Sep 21. Bioorg Med Chem Lett. 2011. PMID: 21983444