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10,219 results

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Page 1
Showing results for viral nc
Search for Vidal NC instead (2 results)
Nucleocapsid assembly drives Ebola viral factory maturation and dispersion.
Vallbracht M, Bodmer BS, Fischer K, Makroczyova J, Winter SL, Wendt L, Wachsmuth-Melm M, Hoenen T, Chlanda P. Vallbracht M, et al. Cell. 2025 Feb 6;188(3):704-720.e17. doi: 10.1016/j.cell.2024.11.024. Epub 2024 Dec 31. Cell. 2025. PMID: 39742805 Free article.
Replication and genome encapsidation of many negative-sense RNA viruses take place in virus-induced membraneless organelles termed viral factories (VFs). Although liquid properties of VFs are believed to control the transition from genome replication to nucleocapsid (NC …
Replication and genome encapsidation of many negative-sense RNA viruses take place in virus-induced membraneless organelles termed viral …
Nucleocapsid proteins: roles beyond viral RNA packaging.
Ding B, Qin Y, Chen M. Ding B, et al. Wiley Interdiscip Rev RNA. 2016 Mar-Apr;7(2):213-26. doi: 10.1002/wrna.1326. Epub 2016 Jan 8. Wiley Interdiscip Rev RNA. 2016. PMID: 26749541 Free PMC article. Review.
Viral nucleocapsid proteins (NCs) enwrap the RNA genomes of viruses to form NC-RNA complexes, which act as a template and are essential for viral replication and transcription. Beyond packaging viral RNA, NCs also play important roles in virus replicat …
Viral nucleocapsid proteins (NCs) enwrap the RNA genomes of viruses to form NC-RNA complexes, which act as a template and are …
Recent insights into N(6)-methyladenosine during viral infection.
Horner SM, Reaves JV. Horner SM, et al. Curr Opin Genet Dev. 2024 Aug;87:102213. doi: 10.1016/j.gde.2024.102213. Epub 2024 Jun 19. Curr Opin Genet Dev. 2024. PMID: 38901100 Free PMC article. Review.
The RNA modification of N(6)-methyladenosine (m(6)A) controls many aspects of RNA function that impact biological processes, including viral infection. In this review, we highlight recent work that shapes our current understanding of the diverse mechanisms by which m(6)A c …
The RNA modification of N(6)-methyladenosine (m(6)A) controls many aspects of RNA function that impact biological processes, including vi …
Filovirus Filament Proteins.
Beniac DR, Lamboo LL, Booth TF. Beniac DR, et al. Subcell Biochem. 2018;88:73-94. doi: 10.1007/978-981-10-8456-0_4. Subcell Biochem. 2018. PMID: 29900493 Review.
The filovirus ribonucleoprotein forms a highly organized double-layered helical nucleocapsid (NC) containing five different virally encoded proteins. The inner layer consists of NP, the RNA binding protein, complexed with the monopartite linear genome. ...There is a …
The filovirus ribonucleoprotein forms a highly organized double-layered helical nucleocapsid (NC) containing five different virall …
Topology-Driven Discovery of Transmembrane Protein S-Palmitoylation.
Forrester MT, Egol JR, Ozbay S, Singh R, Tata PR. Forrester MT, et al. bioRxiv [Preprint]. 2024 Sep 8:2024.09.08.611865. doi: 10.1101/2024.09.08.611865. bioRxiv. 2024. Update in: J Biol Chem. 2025 Mar;301(3):108259. doi: 10.1016/j.jbc.2025.108259. PMID: 39282397 Free PMC article. Updated. Preprint.
Within transmembrane proteins (TMPs), S-palmitoylation is implicated in conditions from inflammatory disorders to respiratory viral infections. Many small-scale experiments have observed S-palmitoylation at juxtamembrane Cys residues. ...Utilizing a UniProt-derived feature …
Within transmembrane proteins (TMPs), S-palmitoylation is implicated in conditions from inflammatory disorders to respiratory viral i …
Viral pathogens increase risk of neurodegenerative disease.
Blackhurst BM, Funk KE. Blackhurst BM, et al. Nat Rev Neurol. 2023 May;19(5):259-260. doi: 10.1038/s41582-023-00790-6. Nat Rev Neurol. 2023. PMID: 36864169 Free PMC article.
A new study, drawing on data from national biobanks, adds to the growing evidence that exposure to common viral pathogens increases the risk of Alzheimer disease and other neurodegenerative diseases. ...
A new study, drawing on data from national biobanks, adds to the growing evidence that exposure to common viral pathogens increases t …
Residual inflammation and viral reservoirs: alliance against an HIV cure.
Massanella M, Fromentin R, Chomont N. Massanella M, et al. Curr Opin HIV AIDS. 2016 Mar;11(2):234-41. doi: 10.1097/COH.0000000000000230. Curr Opin HIV AIDS. 2016. PMID: 26575148 Free PMC article. Review.
PURPOSE OF REVIEW: HIV persists in cellular and anatomical reservoirs during antiretroviral therapy (ART). Viral persistence is ensured by a variety of mechanisms including ongoing viral replication and proliferation of latently infected cells. ...Therefore, reducin …
PURPOSE OF REVIEW: HIV persists in cellular and anatomical reservoirs during antiretroviral therapy (ART). Viral persistence is ensur …
Non-coding RNAs: novel players in chromatin-regulation during viral latency.
Eilebrecht S, Schwartz C, Rohr O. Eilebrecht S, et al. Curr Opin Virol. 2013 Aug;3(4):387-93. doi: 10.1016/j.coviro.2013.04.001. Epub 2013 May 6. Curr Opin Virol. 2013. PMID: 23660570 Review.
The heterochromatin-mediated repression of lytic viral genes results in viral latency, enabling the virus to persist dormant without being recognized by the host immune system, but keeping the potential for reactivation. ...In this review we give an overview of chro …
The heterochromatin-mediated repression of lytic viral genes results in viral latency, enabling the virus to persist dormant w …
Microvesicles and viral infection.
Meckes DG Jr, Raab-Traub N. Meckes DG Jr, et al. J Virol. 2011 Dec;85(24):12844-54. doi: 10.1128/JVI.05853-11. Epub 2011 Oct 5. J Virol. 2011. PMID: 21976651 Free PMC article. Review.
Apparent differences include the complexity of viral entry, temporally regulated viral expression, and self-replication proceeding to infection of new cells. Interestingly, many virally infected cells secrete microvesicles that differ in content from their vi …
Apparent differences include the complexity of viral entry, temporally regulated viral expression, and self-replication procee …
Rotavirus NSP2: A Master Orchestrator of Early Viral Particle Assembly.
Nichols SL, Haller C, Borodavka A, Esstman SM. Nichols SL, et al. Viruses. 2024 May 21;16(6):814. doi: 10.3390/v16060814. Viruses. 2024. PMID: 38932107 Free PMC article. Review.
Early RV particle assembly is a multi-step process that includes the assortment, packaging and replication of the 11 genome segments in close connection with capsid morphogenesis. This process occurs inside virally induced, cytosolic, membrane-less organelles called viropl …
Early RV particle assembly is a multi-step process that includes the assortment, packaging and replication of the 11 genome segments in clos …
10,219 results
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