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Page 1
A Landscape of Pharmacogenomic Interactions in Cancer.
Iorio F, Knijnenburg TA, Vis DJ, Bignell GR, Menden MP, Schubert M, Aben N, Gonçalves E, Barthorpe S, Lightfoot H, Cokelaer T, Greninger P, van Dyk E, Chang H, de Silva H, Heyn H, Deng X, Egan RK, Liu Q, Mironenko T, Mitropoulos X, Richardson L, Wang J, Zhang T, Moran S, Sayols S, Soleimani M, Tamborero D, Lopez-Bigas N, Ross-Macdonald P, Esteller M, Gray NS, Haber DA, Stratton MR, Benes CH, Wessels LFA, Saez-Rodriguez J, McDermott U, Garnett MJ. Iorio F, et al. Among authors: vis dj. Cell. 2016 Jul 28;166(3):740-754. doi: 10.1016/j.cell.2016.06.017. Epub 2016 Jul 7. Cell. 2016. PMID: 27397505 Free PMC article.
Effective drug combinations in breast, colon and pancreatic cancer cells.
Jaaks P, Coker EA, Vis DJ, Edwards O, Carpenter EF, Leto SM, Dwane L, Sassi F, Lightfoot H, Barthorpe S, van der Meer D, Yang W, Beck A, Mironenko T, Hall C, Hall J, Mali I, Richardson L, Tolley C, Morris J, Thomas F, Lleshi E, Aben N, Benes CH, Bertotti A, Trusolino L, Wessels L, Garnett MJ. Jaaks P, et al. Among authors: vis dj. Nature. 2022 Mar;603(7899):166-173. doi: 10.1038/s41586-022-04437-2. Epub 2022 Feb 23. Nature. 2022. PMID: 35197630 Free PMC article.
Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients.
Ooft SN, Weeber F, Dijkstra KK, McLean CM, Kaing S, van Werkhoven E, Schipper L, Hoes L, Vis DJ, van de Haar J, Prevoo W, Snaebjornsson P, van der Velden D, Klein M, Chalabi M, Boot H, van Leerdam M, Bloemendal HJ, Beerepoot LV, Wessels L, Cuppen E, Clevers H, Voest EE. Ooft SN, et al. Among authors: vis dj. Sci Transl Med. 2019 Oct 9;11(513):eaay2574. doi: 10.1126/scitranslmed.aay2574. Sci Transl Med. 2019. PMID: 31597751
NASP modulates histone turnover to drive PARP inhibitor resistance.
Moser SC, Khalizieva A, Roehsner J, Pottendorfer E, Kaptein ML, Ricci G, Bhardwaj V, Bleijerveld OB, Hoekman L, van der Heijden I, di Sanzo S, Fish A, Chikunova A, Haarhuis JHI, Oldenkamp R, Robbez-Masson L, Sprengers J, Vis DJ, Wessels LFA, van de Ven M, Pettitt SJ, Tutt ANJ, Lord CJ, Rowland BD, Völker-Albert M, Mattiroli F, Brummelkamp TR, Mazouzi A, Jonkers J. Moser SC, et al. Among authors: vis dj. Nature. 2025 Sep;645(8082):1071-1080. doi: 10.1038/s41586-025-09414-z. Epub 2025 Aug 13. Nature. 2025. PMID: 40804522
Genomic and transcriptomic features of androgen receptor signaling inhibitor resistance in metastatic castration-resistant prostate cancer.
Zhu X, Farsh T, Vis D, Yu I, Li H, Liu T, Sjöström M, Shrestha R, Kneppers J, Severson T, Zhang M, Lundberg A, Moreno Rodriguez T, Weinstein AS, Foye A, Mehra N, Aggarwal RR, Bergman AM, Small EJ, Lack NA, Zwart W, Quigley DA, van der Heijden MS, Feng FY. Zhu X, et al. Among authors: vis d. J Clin Invest. 2024 Aug 13;134(19):e178604. doi: 10.1172/JCI178604. J Clin Invest. 2024. PMID: 39352383 Free PMC article.
Network identification of hormonal regulation.
Vis DJ, Westerhuis JA, Hoefsloot HC, Roelfsema F, van der Greef J, Hendriks MM, Smilde AK. Vis DJ, et al. PLoS One. 2014 May 22;9(5):e96284. doi: 10.1371/journal.pone.0096284. eCollection 2014. PLoS One. 2014. PMID: 24852517 Free PMC article.
Platinum-Based Chemotherapy Induces Opposing Effects on Immunotherapy Response-Related Spatial and Stromal Biomarkers in the Bladder Cancer Microenvironment.
Chelushkin MA, van Dorp J, van Wilpe S, Seignette IM, Mellema JJ, Alkemade M, Gil-Jimenez A, Peters D, Brugman W, Stockem CF, Hooijberg E, Broeks A, van Rhijn BWG, Mertens LS, van der Heijden AG, Mehra N, van Montfoort ML, Wessels LFA, Vis DJ, van der Heijden MS. Chelushkin MA, et al. Among authors: vis dj. Clin Cancer Res. 2024 Sep 13;30(18):4227-4239. doi: 10.1158/1078-0432.CCR-24-0724. Clin Cancer Res. 2024. PMID: 39047168
57 results