Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1951 1
1954 1
1972 3
1973 4
1974 1
1976 3
1977 1
1979 5
1980 2
1981 1
1982 4
1983 5
1984 3
1985 3
1986 3
1987 3
1988 15
1989 5
1990 7
1991 7
1992 6
1993 3
1994 13
1995 15
1996 12
1997 9
1998 15
1999 8
2000 9
2001 8
2002 12
2003 6
2004 9
2005 8
2006 17
2007 8
2008 14
2009 10
2010 13
2011 6
2012 10
2013 8
2014 19
2015 16
2016 15
2017 14
2018 10
2019 16
2020 16
2021 23
2022 13
2023 10
2024 21
2025 9

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

445 results

Results by year

Filters applied: . Clear all
Page 1
Membrane Interaction of the Glycosyltransferase WaaG.
Liebau J, Pettersson P, Szpryngiel S, Mäler L. Liebau J, et al. Biophys J. 2015 Aug 4;109(3):552-63. doi: 10.1016/j.bpj.2015.06.036. Biophys J. 2015. PMID: 26244737 Free PMC article.
We found that the membrane interaction of WaaG is conferred at least in part by MIR-WaaG and that electrostatic interactions play a key role in binding. Moreover, we propose a mechanism of anchoring WaaG to the inner membrane of E. coli, where the central par …
We found that the membrane interaction of WaaG is conferred at least in part by MIR-WaaG and that electrostatic interactions p …
A Lead-Based Fragment Library Screening of the Glycosyltransferase WaaG from Escherichia coli.
Riu F, Ruda A, Engström O, Muheim C, Mobarak H, Ståhle J, Kosma P, Carta A, Daley DO, Widmalm G. Riu F, et al. Pharmaceuticals (Basel). 2022 Feb 9;15(2):209. doi: 10.3390/ph15020209. Pharmaceuticals (Basel). 2022. PMID: 35215321 Free PMC article.
Glucosyl transferase I (WaaG) in E. coli catalyzes the transfer of an alpha-d-glucosyl group to the inner core of the lipopolysaccharide (LPS) and plays an important role in the biogenesis of the outer membrane. ...In the presence of UDP-Glc(2-), the best-docked pose of di …
Glucosyl transferase I (WaaG) in E. coli catalyzes the transfer of an alpha-d-glucosyl group to the inner core of the lipopolysacchar …
New insights into the membrane association mechanism of the glycosyltransferase WaaG from Escherichia coli.
Liebau J, Fu B, Brown C, Mäler L. Liebau J, et al. Biochim Biophys Acta Biomembr. 2018 Mar;1860(3):683-690. doi: 10.1016/j.bbamem.2017.12.004. Epub 2017 Dec 8. Biochim Biophys Acta Biomembr. 2018. PMID: 29225173 Free article.
Here, we studied the applicability of this model to the glycosyltransferase WaaG. WaaG is involved in the synthesis of lipopolysaccharides (LPS) in Gram-negative bacteria and was previously categorized as a monotopic GT. We analyzed the binding of WaaG to mem …
Here, we studied the applicability of this model to the glycosyltransferase WaaG. WaaG is involved in the synthesis of lipopol …
Lipid- and substrate-induced conformational and dynamic changes in a glycosyltransferase involved in E. coli LPS synthesis revealed by 19F and 31P NMR.
Patrick J, Pettersson P, Mäler L. Patrick J, et al. Biochim Biophys Acta Biomembr. 2023 Dec;1865(8):184209. doi: 10.1016/j.bbamem.2023.184209. Epub 2023 Aug 7. Biochim Biophys Acta Biomembr. 2023. PMID: 37558175 Free article.
Using specific 5-fluoro-Trp labelling of native and inserted tryptophans and (19)F NMR we herein studied the dynamic interactions of WaaG with lipids using bicelles, and with the donor substrate. Line-shape changes when bicelles are added to WaaG show that the dynam …
Using specific 5-fluoro-Trp labelling of native and inserted tryptophans and (19)F NMR we herein studied the dynamic interactions of WaaG …
Structural and functional insights into the Pseudomonas aeruginosa glycosyltransferase WaaG and the implications for lipopolysaccharide biosynthesis.
Scaletti ER, Pettersson P, Patrick J, Shilling PJ, Westergren RG, Daley DO, Mäler L, Widmalm G, Stenmark P. Scaletti ER, et al. J Biol Chem. 2023 Oct;299(10):105256. doi: 10.1016/j.jbc.2023.105256. Epub 2023 Sep 15. J Biol Chem. 2023. PMID: 37716703 Free PMC article.
The glycosyltransferase WaaG in Pseudomonas aeruginosa (PaWaaG) is involved in the synthesis of the core region of lipopolysaccharides. ...
The glycosyltransferase WaaG in Pseudomonas aeruginosa (PaWaaG) is involved in the synthesis of the core region of lipopolysaccharide …
Contribution of the gyrA and waaG mutants to fluoroquinolones resistance, biofilm development, and persister cells formation in Salmonella enterica serovar Typhi.
Musanna, Faridoon Khan U, Habib G, Gul H, Hayat A, Ur Rehman M. Musanna, et al. Gene. 2024 Feb 5;894:147943. doi: 10.1016/j.gene.2023.147943. Epub 2023 Nov 11. Gene. 2024. PMID: 37956962
Transcriptional analysis of biofilm associated genes revealed that the waaG gene was significantly downregulated. The deltawaaG mutant showed a significant decrease in persister cells and a strong biofilm formation relative to wild type and gyrA mutant. ...
Transcriptional analysis of biofilm associated genes revealed that the waaG gene was significantly downregulated. The deltawaaG mutan …
Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase.
Landström J, Persson K, Rademacher C, Lundborg M, Wakarchuk W, Peters T, Widmalm G. Landström J, et al. Glycoconj J. 2012 Oct;29(7):491-502. doi: 10.1007/s10719-012-9411-4. Epub 2012 Jun 19. Glycoconj J. 2012. PMID: 22711644
The alpha-1,3-glucosyltransferase WaaG is involved in the synthesis of the core region of lipopolysaccharides in E. coli. ...Molecular dynamics simulations of WaaG were carried out with and without bound UDP and revealed structural changes compared to the crystal st …
The alpha-1,3-glucosyltransferase WaaG is involved in the synthesis of the core region of lipopolysaccharides in E. coli. ...Molecula …
Identification of a Fragment-Based Scaffold that Inhibits the Glycosyltransferase WaaG from Escherichia coli.
Muheim C, Bakali A, Engström O, Wieslander Å, Daley DO, Widmalm G. Muheim C, et al. Antibiotics (Basel). 2016 Jan 28;5(1):10. doi: 10.3390/antibiotics5010010. Antibiotics (Basel). 2016. PMID: 27025525 Free PMC article.
WaaG is a glycosyltransferase that is involved in the biosynthesis of lipopolysaccharide in Gram-negative bacteria. ...Herein, we establish an activity assay for WaaG using (14)C-labeled UDP-glucose and LPS purified from a waaG strain of Escherichia coli. ...
WaaG is a glycosyltransferase that is involved in the biosynthesis of lipopolysaccharide in Gram-negative bacteria. ...Herein, we est …
Analysis of behavioral flow resolves latent phenotypes.
von Ziegler LM, Roessler FK, Sturman O, Waag R, Privitera M, Duss SN, O'Connor EC, Bohacek J. von Ziegler LM, et al. Nat Methods. 2024 Dec;21(12):2376-2387. doi: 10.1038/s41592-024-02500-6. Epub 2024 Nov 12. Nat Methods. 2024. PMID: 39533008 Free PMC article.
445 results