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Interim analysis of the long-term efficacy and safety of azetukalner in an ongoing open-label extension study following a phase 2b clinical trial (X-TOLE) in adults with focal epilepsy.
Epilepsia Open. 2025 Apr;10(2):539-548. doi: 10.1002/epi4.70015. Epub 2025 Mar 7.
Epilepsia Open. 2025.
PMID: 40053315
Free PMC article.
Clinical Trial.
Efficacy and Safety of XEN1101, a Novel Potassium Channel Opener, in Adults With Focal Epilepsy: A Phase 2b Randomized Clinical Trial.
French JA, Porter RJ, Perucca E, Brodie MJ, Rogawski MA, Pimstone S, Aycardi E, Harden C, Qian J, Rosenblut CL, Kenney C, Beatch GN; X-TOLE Study Group.
French JA, et al.
JAMA Neurol. 2023 Nov 1;80(11):1145-1154. doi: 10.1001/jamaneurol.2023.3542.
JAMA Neurol. 2023.
PMID: 37812429
Free PMC article.
Clinical Trial.
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