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. 1984 Nov;312(5989):36-40.
doi: 10.1038/312036a0.

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

H Saito, D M Kranz, Y Takagaki, A C Hayday, H N Eisen, S Tonegawa

A third rearranged and expressed gene in a clone of cytotoxic T lymphocytes

H Saito et al. Nature. 1984 Nov.

Abstract

In addition to the two previously identified genes rearranged and expressed in a cytotoxic T-lymphocyte clone, we have identified a third gene that is also rearranged and expressed in the same clone. This new gene shows clonal diversity, codes for a polypeptide chain that contains immunoglobulin-like variable and constant domains, carries potential N-glycosylation sites and is a particularly attractive candidate for the gene that encodes the alpha-subunit of the heterodimeric antigen receptor of this T-cell clone.

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