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. 1986 Jan 24;14(2):797-809.
doi: 10.1093/nar/14.2.797.

The sequence and structure of a new serum amyloid A gene

R S Stearman, C A Lowell, C G Peltzman, J F Morrow
Free PMC article

The sequence and structure of a new serum amyloid A gene

R S Stearman et al. Nucleic Acids Res. .
Free PMC article

Abstract

The acute phase response is characterized by changes in the serum concentrations of many proteins. A 1000-fold increase in the concentration of serum amyloid A (SAA) protein occurs within 24 hours of LPS injection in the mouse. We have isolated a cDNA clone and its corresponding genomic phage for a third, previously unreported SAA protein. The sequence of the cDNA, the gene's exons and neighboring DNA are presented along with the mapping evidence supporting the gene structure.

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