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. 1986 Mar;320(6059):232-8.
doi: 10.1038/320232a0.

Transfer of specificity by murine alpha and beta T-cell receptor genes

Z Dembić, W Haas, S Weiss, J McCubrey, H Kiefer, H von Boehmer, M Steinmetz

Transfer of specificity by murine alpha and beta T-cell receptor genes

Z Dembić et al. Nature. 1986 Mar.

Abstract

T-cell receptor alpha- and beta-chain genes were isolated from a class I major histocompatibility complex-restricted cytotoxic T-cell clone and transferred by protoplast fusion into another cytolytic T-cell clone of different specificity. Expression of the transfected alpha and beta genes endowed the recipient cell with the specificity of the donor cell.

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