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. 1988 Sep 12;16(17):8433-42.
doi: 10.1093/nar/16.17.8433.

Mitochondrial DNA of the yeast Kluyveromyces: guanine-cytosine rich sequence clusters

A Ragnini  1 , H Fukuhara
Affiliations

Mitochondrial DNA of the yeast Kluyveromyces: guanine-cytosine rich sequence clusters

A Ragnini et al. Nucleic Acids Res. .

Abstract

Mitochondrial DNA from the yeast Kluyveromyces marxianus var. lactis (K.lactis) is a circular molecule of 39 kilobase-pairs. A genetic and physical map was constructed. We found that this genome contained a large number of guanine-cytosine (GC)-rich sequence clusters, many of which are characterized by the presence of SacII restriction sites (CCGCGG). The primary sequence of the GC clusters often showed a palindromic structure. These GC clusters were present in several varieties of K.marxianus, but not in others. The presence of these clusters is a major feature that distinguishes K.lactis strains from those of K.marxianus var. marxianus (including K.fragilis).

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