Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1990 Dec;348(6303):699-704.
doi: 10.1038/348699a0.

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

P Basset  1 , J P Bellocq, C Wolf, I Stoll, P Hutin, J M Limacher, O L Podhajcer, M P Chenard, M C Rio, P Chambon
Affiliations

A novel metalloproteinase gene specifically expressed in stromal cells of breast carcinomas

P Basset et al. Nature. 1990 Dec.

Abstract

A gene has been identified that is expressed specifically in stromal cells surrounding invasive breast carcinomas. On the basis of its sequence, the product of this gene, named stromelysin-3, is a new member of the family of metalloproteinase enzymes which degrade the extracellular matrix. The suggestion is that stromelysin-3 is one of the stroma-derived factors that have long been postulated to play an important part in progression of epithelial malignancies.

PubMed Disclaimer

Publication types

Associated data