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Year Number of Results
2003 1
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2007 3
2008 3
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2010 2
2011 1
2012 4
2013 2
2014 1
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2017 3
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2019 8
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74 results

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Page 1
Covalent inhibition of pro-apoptotic BAX.
McHenry MW, Shi P, Camara CM, Cohen DT, Rettenmaier TJ, Adhikary U, Gygi MA, Yang K, Gygi SP, Wales TE, Engen JR, Wells JA, Walensky LD. McHenry MW, et al. Among authors: yang k. Nat Chem Biol. 2024 Aug;20(8):1022-1032. doi: 10.1038/s41589-023-01537-6. Epub 2024 Jan 17. Nat Chem Biol. 2024. PMID: 38233584 Free PMC article.
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation.
Kagiou C, Cisneros JA, Farnung J, Liwocha J, Offensperger F, Dong K, Yang K, Tin G, Horstmann CS, Hinterndorfer M, Paulo JA, Scholes NS, Sanchez Avila J, Fellner M, Andersch F, Hannich JT, Zuber J, Kubicek S, Gygi SP, Schulman BA, Winter GE. Kagiou C, et al. Among authors: yang k. Nat Commun. 2024 Jun 26;15(1):5409. doi: 10.1038/s41467-024-49739-3. Nat Commun. 2024. PMID: 38926334 Free PMC article.
Human and mouse proteomics reveals the shared pathways in Alzheimer's disease and delayed protein turnover in the amyloidome.
Yarbro JM, Han X, Dasgupta A, Yang K, Liu D, Shrestha HK, Zaman M, Wang Z, Yu K, Lee DG, Vanderwall D, Niu M, Sun H, Xie B, Chen PC, Jiao Y, Zhang X, Wu Z, Chepyala SR, Fu Y, Li Y, Yuan ZF, Wang X, Poudel S, Vagnerova B, He Q, Tang A, Ronaldson PT, Chang R, Yu G, Liu Y, Peng J. Yarbro JM, et al. Among authors: yang k. Nat Commun. 2025 Feb 11;16(1):1533. doi: 10.1038/s41467-025-56853-3. Nat Commun. 2025. PMID: 39934151 Free PMC article.
Potent and selective SETDB1 covalent negative allosteric modulator reduces methyltransferase activity in cells.
Uguen M, Shell DJ, Silva M, Deng Y, Li F, Szewczyk MM, Yang K, Zhao Y, Stashko MA, Norris-Drouin JL, Waybright JM, Beldar S, Rectenwald JM, Mordant AL, Webb TS, Herring LE, Arrowsmith CH, Ackloo S, Gygi SP, McGinty RK, Barsyte-Lovejoy D, Liu P, Halabelian L, James LI, Pearce KH, Frye SV. Uguen M, et al. Among authors: yang k. Nat Commun. 2025 Feb 24;16(1):1905. doi: 10.1038/s41467-025-57005-3. Nat Commun. 2025. PMID: 39994194 Free PMC article.
Potent and Selective SETDB1 Covalent Negative Allosteric Modulator Reduces Methyltransferase Activity in Cells.
Uguen M, Shell DJ, Silva M, Deng Y, Li F, Szewczyk MM, Yang K, Zhao Y, Stashko MA, Norris-Drouin JL, Waybright JM, Beldar S, Rectenwald JM, Mordant AL, Webb TS, Herring LE, Arrowsmith CH, Ackloo S, Gygi SP, McGinty RK, Barsyte-Lovejoy D, Liu P, Halabelian L, James LI, Pearce KH, Frye SV. Uguen M, et al. Among authors: yang k. bioRxiv [Preprint]. 2024 Sep 28:2024.09.27.615363. doi: 10.1101/2024.09.27.615363. bioRxiv. 2024. Update in: Nat Commun. 2025 Feb 24;16(1):1905. doi: 10.1038/s41467-025-57005-3. PMID: 39386588 Free PMC article. Updated. Preprint.
Characterization of a dual degrader of MDM2 and GSPT1.
Tandon I, Esguerra PN, Li C, Sun H, Yang K, Zhang Z, Peng J, Tang W. Tandon I, et al. Among authors: yang k. Eur J Med Chem. 2025 Oct 5;295:117793. doi: 10.1016/j.ejmech.2025.117793. Epub 2025 May 21. Eur J Med Chem. 2025. PMID: 40440791
An Extensive Atlas of Proteome and Phosphoproteome Turnover Across Mouse Tissues and Brain Regions.
Li W, Dasgupta A, Yang K, Wang S, Hemandhar-Kumar N, Yarbro JM, Hu Z, Salovska B, Fornasiero EF, Peng J, Liu Y. Li W, et al. Among authors: yang k. bioRxiv [Preprint]. 2024 Oct 17:2024.10.15.618303. doi: 10.1101/2024.10.15.618303. bioRxiv. 2024. Update in: Cell. 2025 Apr 17;188(8):2267-2287.e21. doi: 10.1016/j.cell.2025.02.021. PMID: 39464138 Free PMC article. Updated. Preprint.
74 results