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Circulating tumor DNA-guided adjuvant therapy in locally advanced colon cancer: the randomized phase 2/3 DYNAMIC-III trial.
Tie J, Wang Y, Loree JM, Cohen JD, Wong R, Price T, Tebbutt NC, Gebski V, Espinoza D, Burge M, Harris S, Lynam J, Lee B, Lee MM, Breadner D, Debrincat M, Foroughi S, Chantrill L, Lim SH, Gill S, O'Callaghan C, Ptak J, Silliman N, Dobbyn L, Popoli M, Bettegowda C, Papadopoulos N, Kinzler KW, Vogelstein B, Gibbs P; AGITG DYNAMIC-III Study Group (Intergroup Study of the Australasian Gastro-Intestinal Trials Group and Canadian Cancer Trials Group). Tie J, et al. Nat Med. 2025 Dec;31(12):4291-4300. doi: 10.1038/s41591-025-04030-w. Epub 2025 Oct 20. Nat Med. 2025. PMID: 41115959 Clinical Trial.
A phase I study of binimetinib (MEK 162), a MEK inhibitor, plus carboplatin and pemetrexed chemotherapy in non-squamous non-small cell lung cancer.
Fung AS, Graham DM, Chen EX, Stockley TL, Zhang T, Le LW, Albaba H, Pisters KM, Bradbury PA, Trinkaus M, Chan M, Arif S, Zurawska U, Rothenstein J, Zawisza D, Effendi S, Gill S, Sawczak M, Law JH, Leighl NB. Fung AS, et al. Among authors: zurawska u. Lung Cancer. 2021 Jul;157:21-29. doi: 10.1016/j.lungcan.2021.05.021. Epub 2021 May 24. Lung Cancer. 2021. PMID: 34052705 Clinical Trial.