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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1951 1
1953 1
1956 1
1971 2
1974 1
1975 1
1977 2
1978 1
1979 2
1980 1
1981 1
1983 7
1984 2
1985 1
1986 3
1987 2
1988 4
1989 6
1990 5
1991 4
1992 3
1993 3
1994 8
1995 3
1996 10
1997 8
1998 4
1999 4
2000 11
2001 9
2002 6
2003 12
2004 11
2005 19
2006 16
2007 13
2008 10
2009 19
2010 17
2011 11
2012 22
2013 16
2014 19
2015 20
2016 16
2017 21
2018 13
2019 30
2020 26
2021 28
2022 25
2023 26
2024 24
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517 results

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Page 1
Emerging debates and resolutions in brown adipose tissue research.
Cypess AM, Cannon B, Nedergaard J, Kazak L, Chang DC, Krakoff J, Tseng YH, Schéele C, Boucher J, Petrovic N, Blondin DP, Carpentier AC, Virtanen KA, Kooijman S, Rensen PCN, Cero C, Kajimura S. Cypess AM, et al. Cell Metab. 2025 Jan 7;37(1):12-33. doi: 10.1016/j.cmet.2024.11.002. Epub 2024 Dec 6. Cell Metab. 2025. PMID: 39644896 Review.
MCC950 directly targets the NLRP3 ATP-hydrolysis motif for inflammasome inhibition.
Coll RC, Hill JR, Day CJ, Zamoshnikova A, Boucher D, Massey NL, Chitty JL, Fraser JA, Jennings MP, Robertson AAB, Schroder K. Coll RC, et al. Nat Chem Biol. 2019 Jun;15(6):556-559. doi: 10.1038/s41589-019-0277-7. Epub 2019 May 13. Nat Chem Biol. 2019. PMID: 31086327
Here, we show that MCC950 directly interacts with the Walker B motif within the NLRP3 NACHT domain, thereby blocking ATP hydrolysis and inhibiting NLRP3 activation and inflammasome formation....
Here, we show that MCC950 directly interacts with the Walker B motif within the NLRP3 NACHT domain, thereby blocking ATP hydrolysis a …
Application of human liver organoids as a patient-derived primary model for HBV infection and related hepatocellular carcinoma.
De Crignis E, Hossain T, Romal S, Carofiglio F, Moulos P, Khalid MM, Rao S, Bazrafshan A, Verstegen MM, Pourfarzad F, Koutsothanassis C, Gehart H, Kan TW, Palstra RJ, Boucher C, IJzermans JN, Huch M, Boj SF, Vries R, Clevers H, van der Laan LJ, Hatzis P, Mahmoudi T. De Crignis E, et al. Elife. 2021 Jul 30;10:e60747. doi: 10.7554/eLife.60747. Elife. 2021. PMID: 34328417 Free PMC article.
The molecular events that drive hepatitis B virus (HBV)-mediated transformation and tumorigenesis have remained largely unclear, due to the absence of a relevant primary model system. ...
The molecular events that drive hepatitis B virus (HBV)-mediated transformation and tumorigenesis have remained largely unclear, due …
Vector Strategies to Actualize B Cell-Based Gene Therapies.
Jeske AM, Boucher P, Curiel DT, Voss JE. Jeske AM, et al. J Immunol. 2021 Aug 1;207(3):755-764. doi: 10.4049/jimmunol.2100340. J Immunol. 2021. PMID: 34321286 Free PMC article. Review.
Recent developments in genome editing and delivery systems have opened new possibilities for B cell gene therapy. CRISPR-Cas9 nucleases have been used to introduce transgenes into B cell genomes for subsequent secretion of exogenous therapeutic proteins from plasma …
Recent developments in genome editing and delivery systems have opened new possibilities for B cell gene therapy. CRISPR-Cas9 nucleas …
Proximal and Distal Bronchioles Contribute to the Pathogenesis of Non-Cystic Fibrosis Bronchiectasis.
Asakura T, Okuda K, Chen G, Dang H, Kato T, Mikami Y, Schworer SA, Gilmore RC, Radicioni G, Hawkins P, Barbosa Cardenas SM, Saito M, Cawley AM, De la Cruz G, Chua M, Alexis NE, Masugi Y, Noone PG, Ribeiro CMP, Kesimer M, Olivier KN, Hasegawa N, Randell SH, O'Neal WK, Boucher RC. Asakura T, et al. Am J Respir Crit Care Med. 2024 Feb 15;209(4):374-389. doi: 10.1164/rccm.202306-1093OC. Am J Respir Crit Care Med. 2024. PMID: 38016030 Free PMC article.
Screening of donor and candidate prior to solid organ transplantation-Guidelines from the American Society of Transplantation Infectious Diseases Community of Practice.
Malinis M, Boucher HW; AST Infectious Diseases Community of Practice. Malinis M, et al. Clin Transplant. 2019 Sep;33(9):e13548. doi: 10.1111/ctr.13548. Epub 2019 Apr 29. Clin Transplant. 2019. PMID: 30900327
In addition to serology, nucleic acid testing for hepatitis B, hepatitis C and human immunodeficiency virus has been required for deceased and living donors. ...
In addition to serology, nucleic acid testing for hepatitis B, hepatitis C and human immunodeficiency virus has been required for dec …
517 results