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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1948 2
1949 1
1950 3
1951 4
1954 5
1955 3
1956 4
1957 1
1958 4
1959 3
1960 3
1962 10
1963 4
1964 2
1966 2
1967 4
1968 4
1969 7
1970 6
1971 5
1972 3
1973 1
1974 1
1975 12
1976 18
1977 8
1978 11
1979 13
1980 12
1981 12
1982 17
1983 12
1984 14
1985 15
1986 20
1987 10
1988 15
1989 27
1990 30
1991 23
1992 30
1993 23
1994 19
1995 31
1996 26
1997 34
1998 37
1999 26
2000 24
2001 47
2002 44
2003 52
2004 52
2005 79
2006 76
2007 86
2008 82
2009 82
2010 99
2011 105
2012 99
2013 95
2014 118
2015 108
2016 92
2017 97
2018 96
2019 104
2020 91
2021 102
2022 108
2023 70
2024 80
2025 62

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2,530 results

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Page 1
Communication networks in the brain: neurons, receptors, neurotransmitters, and alcohol.
Lovinger DM. Lovinger DM. Alcohol Res Health. 2008;31(3):196-214. Alcohol Res Health. 2008. PMID: 23584863 Free PMC article. Review.
Communication between neurons occurs at tiny gaps called synapses, where specialized parts of the two cells (i.e., the presynaptic and postsynaptic neurons) come within nanometers of one another to allow for chemical transmission. ...Two types of neurotransmitter receptors …
Communication between neurons occurs at tiny gaps called synapses, where specialized parts of the two cells (i.e., the presynaptic an …
A Mast-Cell-Specific Receptor Mediates Neurogenic Inflammation and Pain.
Green DP, Limjunyawong N, Gour N, Pundir P, Dong X. Green DP, et al. Neuron. 2019 Feb 6;101(3):412-420.e3. doi: 10.1016/j.neuron.2019.01.012. Epub 2019 Jan 24. Neuron. 2019. PMID: 30686732 Free PMC article.
However, the precise mechanism underlying this so-called neurogenic inflammation and associated pain has remained elusive. Here we report that the mast-cell-specific receptor Mrgprb2 mediates inflammatory mechanical and thermal hyperalgesia and is required for recruitment …
However, the precise mechanism underlying this so-called neurogenic inflammation and associated pain has remained elusive. Here we re …
G-Protein-Coupled Receptors in Astrocyte-Neuron Communication.
Kofuji P, Araque A. Kofuji P, et al. Neuroscience. 2021 Feb 21;456:71-84. doi: 10.1016/j.neuroscience.2020.03.025. Epub 2020 Mar 26. Neuroscience. 2021. PMID: 32224231 Free PMC article. Review.
Astrocytes express a wide variety of neurotransmitter transporters and receptors that allow them to sense and respond to synaptic activity. Principal among them are the G-protein-coupled receptors (GPCRs) in astrocytes because their activation by synaptically released neur …
Astrocytes express a wide variety of neurotransmitter transporters and receptors that allow them to sense and respond to synaptic activity. …
[Biased Signaling through G Protein-coupled Receptors].
Kurose H. Kurose H. Yakugaku Zasshi. 2022;142(10):1091-1101. doi: 10.1248/yakushi.22-00087. Yakugaku Zasshi. 2022. PMID: 36184444 Free article. Review. Japanese.
It is well-established that G protein-coupled receptors (GPCRs) transduce signals into cells using G proteins as intermediary molecules. beta-Arrestins are molecules involved in regulating GPCRs; however, it has recently been reported that beta-arrestins can also me …
It is well-established that G protein-coupled receptors (GPCRs) transduce signals into cells using G proteins as intermediary …
An Insight into GPCR and G-Proteins as Cancer Drivers.
Chaudhary PK, Kim S. Chaudhary PK, et al. Cells. 2021 Nov 24;10(12):3288. doi: 10.3390/cells10123288. Cells. 2021. PMID: 34943797 Free PMC article. Review.
G-protein-coupled receptors (GPCRs) are the largest family of cell surface signaling receptors known to play a crucial role in various physiological functions, including tumor growth and metastasis. Various molecules such as hormones, lipids, peptides, and neurotransmitter …
G-protein-coupled receptors (GPCRs) are the largest family of cell surface signaling receptors known to play a crucial role in variou …
IgG4 disease.
Yamamoto M, Hashimoto M, Takahashi H, Shinomura Y. Yamamoto M, et al. J Neuroophthalmol. 2014 Dec;34(4):393-9. doi: 10.1097/WNO.0000000000000172. J Neuroophthalmol. 2014. PMID: 25405661 Review.
Immunoglobulin (Ig) G4-related disease (IgG4-RD) is a chronic inflammatory disorder characterized by elevated serum level of IgG4 and abundant infiltration of IgG4-bearing plasmacytes and fibrosis in various organs, typically including the lacrimal glands, salivary glands, pancre …
Immunoglobulin (Ig) G4-related disease (IgG4-RD) is a chronic inflammatory disorder characterized by elevated serum level of IgG4 and abunda …
Reductionism redux.
Miller C. Miller C. Elife. 2016 May 13;5:e16964. doi: 10.7554/eLife.16964. Elife. 2016. PMID: 27175739 Free PMC article.
Experiments on artificial membranes are revealing many details about the workings of a family of potassium ion channels called GIRK channels....
Experiments on artificial membranes are revealing many details about the workings of a family of potassium ion channels called GIRK c …
beta-arrestins and G protein-coupled receptor trafficking.
Tian X, Kang DS, Benovic JL. Tian X, et al. Handb Exp Pharmacol. 2014;219:173-86. doi: 10.1007/978-3-642-41199-1_9. Handb Exp Pharmacol. 2014. PMID: 24292830 Free PMC article. Review.
Nonvisual arrestins (beta-arrestin-1 and beta-arrestin-2) are adaptor proteins that function to regulate G protein-coupled receptor (GPCR) signaling and trafficking. beta-arrestins are ubiquitously expressed and function to inhibit GPCR/G protein coupling, a process …
Nonvisual arrestins (beta-arrestin-1 and beta-arrestin-2) are adaptor proteins that function to regulate G protein-coupled receptor ( …
Flavors of GPCR signaling bias.
Seyedabadi M, Gurevich VV. Seyedabadi M, et al. Neuropharmacology. 2024 Dec 15;261:110167. doi: 10.1016/j.neuropharm.2024.110167. Epub 2024 Sep 19. Neuropharmacology. 2024. PMID: 39306191 Review.
Certain agonists can increase the fraction of active-like conformations that predispose the receptor to coupling to a particular signal transducer or a select group of transducers. Such agonists are called biased, in contrast to balanced agonists that facilitate signaling …
Certain agonists can increase the fraction of active-like conformations that predispose the receptor to coupling to a particular signal tran …
Kisspeptin antagonists.
Roseweir AK, Millar RP. Roseweir AK, et al. Adv Exp Med Biol. 2013;784:159-86. doi: 10.1007/978-1-4614-6199-9_8. Adv Exp Med Biol. 2013. PMID: 23550006 Review.
Kisspeptin binds to its cognate receptor, KISS1R (also called GPR54), on GnRH neurons and stimulates their activity, which in turn provides an obligatory signal for GnRH secretion-thus gating down-stream events supporting reproduction. ...
Kisspeptin binds to its cognate receptor, KISS1R (also called GPR54), on GnRH neurons and stimulates their activity, which in turn pr …
2,530 results