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Rationale and study design for an individualised perioperative open-lung ventilatory strategy with a high versus conventional inspiratory oxygen fraction (iPROVE-O2) and its effects on surgical site infection: study protocol for a randomised controlled trial.
Ferrando C, Soro M, Unzueta C, Canet J, Tusman G, Suarez-Sipmann F, Librero J, Peiró S, Pozo N, Delgado C, Ibáñez M, Aldecoa C, Garutti I, Pestaña D, Rodríguez A, García Del Valle S, Diaz-Cambronero O, Balust J, Redondo FJ, De La Matta M, Gallego L, Granell M, Martínez P, Pérez A, Leal S, Alday K, García P, Monedero P, Gonzalez R, Mazzinari G, Aguilar G, Villar J, Belda FJ; iPROVE-O2 Network Group. Ferrando C, et al. BMJ Open. 2017 Jul 31;7(7):e016765. doi: 10.1136/bmjopen-2017-016765. BMJ Open. 2017. PMID: 28760799 Free PMC article. Clinical Trial.
Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy: a randomised controlled trial.
Ferrando C, Aldecoa C, Unzueta C, Belda FJ, Librero J, Tusman G, Suárez-Sipmann F, Peiró S, Pozo N, Brunelli A, Garutti I, Gallego C, Rodríguez A, García JI, Díaz-Cambronero O, Balust J, Redondo FJ, de la Matta M, Gallego-Ligorit L, Hernández J, Martínez P, Pérez A, Leal S, Alday E, Monedero P, González R, Mazzirani G, Aguilar G, López-Baamonde M, Felipe M, Mugarra A, Torrente J, Valencia L, Varón V, Sánchez S, Rodríguez B, Martín A, India I, Azparren G, Molina R, Villar J, Soro M; iPROVE-O2 Network. Ferrando C, et al. Br J Anaesth. 2020 Jan;124(1):110-120. doi: 10.1016/j.bja.2019.10.009. Epub 2019 Nov 22. Br J Anaesth. 2020. PMID: 31767144 Free article. Clinical Trial.